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Introduction to Health Physics: Fourth Edition - Ruang Baca FMIPA UB

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260 CHAPTER 6<br />

is listed in the output data as 0.058 MeV. A 0.279-MeV gamma ray is emitted after<br />

each beta transformation. The gamma ray, however, is internally converted in 18.3%<br />

of the transformations, thus leading <strong>to</strong> conversion electrons from the K, L, or M<br />

energy levels and, therefore, effective gamma-ray emission occurs in only 81.7% of<br />

the transformations.<br />

Table 6-9 lists the absorbed dose per unit cumulated 203 Hg activity. For the kidneys<br />

as the source, S (kidneys ← kidneys) = 8.1 × 10 −4 rad/μCi · h, and for the <strong>to</strong>tal<br />

body as the source, the dose <strong>to</strong> the kidney, S (kidneys ← <strong>to</strong>tal body) = 6.1 × 10 −6<br />

rad/μCi · h. The <strong>to</strong>tal dose <strong>to</strong> the kidneys is the sum of the doses due <strong>to</strong> the 203 Hg<br />

deposited in the kidneys, and also of the radiomercury in the rest of the body. If<br />

0.5 MBq (13.5 μCi) in the kidneys represents 8% body burden of Hg, then the <strong>to</strong>tal<br />

activity in the body is<br />

0.5 MBq<br />

0.08<br />

= 6.25 MBq (168.9 μCi).<br />

Since 0.5 MBq is in the kidneys, the amount of 203 Hg distributed throughout the<br />

rest of the body is 6.25 − 0.5 = 5.75 MBq.<br />

Of the 6.25 MBq deposited in the body, 95%, or 5.938 MBq, will be eliminated<br />

with an effective half-life, TE, from Eq. (6.54):<br />

TE = TR × TB<br />

=<br />

TR + TB<br />

47 days × 40 days<br />

= 21.6 days,<br />

47 days + 40 days<br />

and the remaining 5% of the deposited 203 Hg will have an effective half-life of<br />

47 days. The corresponding effective clearance rate constants are<br />

and<br />

λ1 = 0.693<br />

21.61 days = 3.2 × 10−2 d −1<br />

λ2 = 0.693<br />

47 days = 1.47 × 10−2 d −1 .<br />

The cumulated activity in the kidney is given by extending Eq. (6.90) <strong>to</strong> several<br />

compartments, c1, c2, ...,cn, within an organ or a tissue is given as<br />

à =<br />

Ac1 (0)<br />

+ Ac2 (0)<br />

λE1<br />

λE2<br />

Acn (0)<br />

+····+ . (6.99)<br />

λEn<br />

From Table 6-9, we find S (kidneys ← kidneys) <strong>to</strong> be 8.1 × 10 −4 rad/μCi · h.<br />

To convert rad/μCi · h<strong>to</strong>Gy/Bq · d:<br />

Gy rad 1Gy<br />

= ×<br />

Bq · d μCi · h 100 rad ×<br />

1 μCi<br />

3.7 × 10 4 Bq<br />

× 24 h<br />

d<br />

Gy rad<br />

=<br />

Bq · d μCi · h × 6.5 × 10−6 . (6.100)<br />

Using the conversion fac<strong>to</strong>r in Eq. (6.100) we find that

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