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Clinical Trials and Preclinical Infrastructure Asset Map - Genome BC

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CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

FIGURE 5. Therapeutic Focus of <strong>Clinical</strong> <strong>Trials</strong> Based on a Number of Studies, 2005/6 - 2009/10<br />

4%<br />

4%<br />

7%<br />

4%<br />

6%<br />

3%<br />

3%<br />

11%<br />

6%<br />

24%<br />

14%<br />

9%<br />

15%<br />

“Other” includes anesthesiology, autoimmune, critical care, dental, dermatology, emergency medicine, hematology, musculo-skeletal,<br />

neonatology, obstetrics <strong>and</strong> gynecology, ophthalmology, surgery, <strong>and</strong> transplant.<br />

The distribution in terms of disease specialty <strong>and</strong> funding of the more than 200 pediatric trials included<br />

in this report is somewhat different to the overall pattern, as can be seen in Figure 7. <strong>Trials</strong> on diseases<br />

<strong>and</strong> disorders of the CNS, particularly epilepsy, Fetal Alcohol Spectrum Disorders, <strong>and</strong> Attention Deficit<br />

Hyperactivity Disorder, are the most common, followed by infectious diseases/ infection (mainly vaccine<br />

trials) 16 . The most common pulmonary trials targeted cystic fibrosis, respiratory syncytial virus, <strong>and</strong><br />

asthma.<br />

23%<br />

17%<br />

23%<br />

18%<br />

9%<br />

Cancer<br />

CV/Cardiology<br />

CNS<br />

ID/Infection<br />

Gastrointestinal<br />

Genitourinary<br />

Metabolic/Endocrine<br />

Pulmonary<br />

Other<br />

FIGURE 6. Therapeutic Focus of <strong>Clinical</strong> <strong>Trials</strong> Based on Amount of Funding, 2005/06 - 2009/10<br />

Cancer<br />

CV/Cardiology<br />

CNS<br />

ID/Infection<br />

Gastrointestinal<br />

Genitourinary<br />

Metabolic/Endocrine<br />

Pulmonary<br />

Other<br />

16 Note that pediatric cancer trials do not come with individual trial funding <strong>and</strong> funding related to disease underestimates the<br />

amount of activity in this area. Using infrastructure funds from the international Children’s Oncology Group (COG), virtually every<br />

child is entered into cancer clinical trials that are seamlessly integrated into their health care.<br />

25

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