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Project duration: from 2006 to 2008 Q. APVV project LPP-0234-06, Chromatographic separation of fruktooligosaccharides (Milan Polakovič) This project is carried within a programme aimed at the stimulation and support of excellent PhD. supervisors. The content of the project is associated with the education of a PhD. student having the topic of the PhD. study identical with the title of the project. Project duration: from 13.11. 2006 to 31.11.2009 R. VEGA project 1/3582/06, Mechanisms and kinetics of enzyme inactivation (Vladimír Štefuca) Enzyme inactivation is a phenomenon, which has unfavorable impact in various areas, such as biocatalytic productions, food processing or application of diagnostic tests. A way to the increase of process stability of enzymes can be a better understanding of their inactivation mechanisms. The primary goal of this project is the investigation of the mechanism of heat and pH inactivation of enzymes in real media, in which the effect of stabilization of enzymes by components of the solution is manifested. The method of identification of inactivation mechanisms is based on a consequent connection of the design of experiments, its performance under a broad range of conditions and evaluation of the kinetics by mathematical modeling. In special cases, the investigation of the mechanism of inactivation will be based on a combined treatment of kinetic data of the loss of enzyme activity and quantities characterizing structural changes, as intensity of laser light scattering or molecular weight distribution obtained by electrophoresis or chromatography. The methods of the investigation of mechanisms are directly related to the elaboration of a procedure for quick determination of process stability of an immobilized biocatalyst in a differential fixed bed reactor. Project duration: from 01.01. 2006 to 31.12.2008 S. VEGA project 1/3565/06, Engineering aspects of chromatographic separation of proteins and saccharides (Milan Polakovič) The project deals with the investigation of engineering aspects of chromatographic separation of a mixture of proteins and saccharides, which are subject of practical interest. Particularly, the purification of IgG, fructosyltransferase (FTase) and fructooligosaccharides (FOS’s) has been studied. A problem of general interest is the investigation of the accessibility of pores by batch and column size-exclusion techniques. The aim is the assessment of advantages, disadvantages and limitations of both techniques and the possibility of interpretation of basic data in the form of pore size distribution. A further part of the project includes investigation of equilibrium and kinetics of adsorption of proteins on affinity and ion-exchange adsorbents by a batch method. The investigation of multi-component adsorption equilibria of saccharides on ion-exchangers will be one of the important parts of the project for their further utilization for modeling and designing separation in a simulated moving bed. In the area of separation of enzymes the project will be aimed at characterizing equilibria in various concentrations of salts, which can be employed in mathematical description of separation using salt gradient. The last area of interest will concern the investigation of kinetics of affinity sorption of FTase on an adsorbent with a bound lectin ligand. Project duration: from 01.01. 2006 to 31.12.2008 V. CURRENT EDUCATION PROJECTS ACU/2005/04/AF/02 A laboratory for testing construction materials for Herat University (Haydary Juma) The project’s objective is to contribute to the improvement of quality of higher engineering education in Afghanistan. The major part of the project is implementation of a laboratory for the testing of construction materials at the Herat University and a training program for teachers, who will manage the laboratory. The overall project outcomes can be formulated as: long-term cooperation between the Herat University and the Slovak University of technology, improvement of the education process and the knowledge and skill of engineering graduates, improvement of knowledge and skill of the teachers of the Faculty of engineering of HU, and increase of the quality and safety of buildings which will be constructed in the region. Project duration: from 2005 to 2007 86
VI. COOPERATION A. Cooperation in Slovakia Institution Type of cooperation Responsible person Duration Rubber Research Institute Matador a.s. Púchov VURUP, a.s., Vlčie hrdlo, Bratislava, Slovakia NCHZ, a.s. Vulcanization conditions influencing the quality and economy of tire production cooperation Engineering contracts Klabník Miroslav, director,Terézie Vansovej 1054/45, 02032 Púchov Mičíková, A., Ing., VURUP, a.s. Vlčie hrdlo, Bratislava, Slovakia Čamaj, V. Goga V., NCHZ, a.s., Nováky continually continually continually EVPÚ, a.s. Engineering contracts A. Jurnečka, EVPÚ, a.s. Since 2006 Liko Bratislava Minárik Martin, Ing., director, Amaranthus exploitation in human food a.s. Wolkrova 4, Bratislava Since 2003 Mráz Igor, Ing. PhD., Since 2003 Liko Bratislava FOODPRO, FP6-project researcher, Miletičova 23, a.s. Bratislava Liko Bratislava Minárik Martin, Ing., director, Production of fructooligosaccharides a.s. Wolkrova 4, Bratislava Since 2004 Technical Búgel M., assoc. professor, co-supervisor of PhD students University Košice Technical University Košice Since 2001 Institute of Gemeiner, Peter, DrSc., Chemistry of the researcher, Institute of Glycerol biosensor development Slovak Academy Chemistry SAS, Dúbravská Since 2003 of Sciences cesta 9, Bratislava Faculty of Mechanical Engineering STU Liko Bratislava a.s. Liko Bratislava a.s. Heat exchanger for blood pasteurization Fermentation of 2-phenylethanol with in -situ extraction of product Microbial proguction of gammadecalactone Ivan Morávek, researcher, Department of Production Systems, nam. Slobody 17, Bratislava Minárik Martin, Ing., director, Wolkrova 4, Bratislava Vladimír Sitkey, Ing., PhD., Wolkrova 4, Bratislava Since 2005 Since 2006 Since 2006 B. International Cooperation Institution Type of cooperation Responsible person Duration ICPF AV ČR cooperation Drahoš, Jiri, professor, ICPF AV ČR continually TU VŠB, Praha, CR cooperation Wichterle, Kamil, professor, TU VŠB, Praha, CR continually Polimi, Milano, I VIRRRTHUALIS, FP 6 project Colombo, Simone, professor, Polimi, Milano, I continually Jose A. Teixeira, professor, Department of Biological University of Minho, ERASMUS Engineering, University of Braga, P Minho, 4710-057 Braga, continually Portugal University of Porto, P ERASMUS L. M. Madeira, professor continually Politehnica Bucurest ERASMUS V. Plesu, professor Since 2006 Technical . B. Kawalec – Pietrenko, ERASMUS University Gdansk professor Since 2006 University of Dortmund, D common projects A. Gorak, professor Since 2001 Herat University common projects Dr. Naim Assad Since 2005 87
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ANNUAL REPORT 2006 Faculty of Chemi
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FOREWORD The Faculty of Chemical an
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B. Research laboratories: Laborator
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signal transducers are investigated
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(Pavol Tarapčík). The project is
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Department of Organic Chemistry, Un
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Kirchner, M. 29th International Sym
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Čacho, F. On-line Preconcentration
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DNA, dsDNA damage and apoptosis in
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[19] Flickyngerová, Soňa, Ovádek
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techniques for ultratrace pesticide
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METHODS. In Absracts of the 29 th I
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Comenius University, Faculty of Pha
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INSTITUTE OF INORGANIC CHEMISTRY, T
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MVTS Project No NEM/Slov/DAAD/Darm0
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Institute of Applied Synthetic Chem
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Koman, M. Institute of Chemical Tec
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Page 54 and 55: Andrea Šovčíková Martin Šimkov
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Page 114 and 115: Project duration: from 01.05.2006 t
Page 116 and 117: Institute of Chemical Technology, P
Page 118 and 119: Hutňan,M. Excursion on Biogas Stat
Page 120 and 121: [12] Derco, Ján, Dudáš, Jozef, J
Page 122 and 123: Optional 2. semester (MSc) Special
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Page 126 and 127: [19] Murárová, A., Podobeková, S
Page 128 and 129: DEPARTMENT OF FOOD SCIENCE AND TECH
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Page 134 and 135: Schmidt, S. Sekretár, S. Zahradní
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[14] Hojerová, J.: Špecifiká koz
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o tenzidech detergentech, Lázne Bo
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B. Undergraduate Study: Technology
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VI. COOPERATION A. Cooperation in S
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VII. THESES AND DISSERTATIONS A. Gr
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DEPARTMENT OF INFORMATION ENGINEERI
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control. Developed algorithms, cont
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Control Engineering Laboratory, FEI
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F. Visits of Staff Members and Post
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[4] Bakošová, M., Baleja, J., Vas
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7. International Scientific-Technic
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5. semester (Bc) Technical English
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DEPARTMENT OF MANAGEMENT Head of De
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TENTO, Inc. Žilina Chemosvit, Inc.
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Name Organisation or Institution St
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VIII. PUBLICATIONS Book [1] Baran,
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[35] Špirko, D.: Globálne marketi
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IV. CURRENT RESEARCH PROJECTS Conju
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C. Membership in Domestic Organizat
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[10] Janiga, I., Mocák, J., Cisko,
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DEPARTMENT OF ORGANIC CHEMISTRY Hea
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APVV project LPP-0238-06 Asymmetric
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Slovak Academy of Sciences, Bratisl
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Lásiková Angelika Slovak Society
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Article in journal [1] Babjak, Mate
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DEPARTMENT OF ORGANIC TECHNOLOGY He
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project in the field of catalytic p
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Hronec M. SC ICT, Praha CR 28. - 29
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[19] Vlčko, Miroslav, Hronec, Mila
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Laboratory practice I 0/0/8 Daučí
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Hudec P. 17th International Congres
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[19] Klepáčová, Katarína, Mrave
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1. semester (MSc) Chemical Physics
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Value Chain (Peter Šimon) FP6 EU p
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F. Visits of Staff Members and Post
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C. Dissertations (PhD) Name Title o
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[52] Šimon, P., Illeková, E., Moj
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the thiphene-thiophene versus pheny
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VIII. PUBLICATIONS Book [1] Bobrík
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Production and Processing of Rubber
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Rubber Research Institute Matador,
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Urogiová E. German Rubber Conferen
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Slovenská konference POLYMERY 2006
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