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Clinical Manual for Management of the HIV-Infected ... - myCME.com

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Esophageal Problems<br />

Background<br />

Esophageal problems in <strong>HIV</strong>-infected patients include<br />

difficulty swallowing (dysphagia) or midline retrosternal<br />

pain when swallowing (odynophagia). Pain may be<br />

diffuse throughout <strong>the</strong> esophagus or localized in specific<br />

areas.<br />

Several conditions may cause esophageal problems.<br />

Of <strong>the</strong> infectious causes <strong>of</strong> dysphagia in <strong>HIV</strong>-infected<br />

patients, Candida is <strong>the</strong> most <strong>com</strong>mon (50-70%). Druginduced<br />

dysphagia, gastroesophageal reflux disease<br />

(GERD), vomiting, and hiatal hernia can also cause<br />

esophagitis. Less <strong>com</strong>monly, neoplasm or ano<strong>the</strong>r cause<br />

<strong>of</strong> stricture may produce symptoms. Neuromuscular<br />

or neurological causes may be seen in patients with<br />

advanced AIDS.<br />

If untreated, esophageal problems may result<br />

in esophageal ulcers, scarring <strong>of</strong> <strong>the</strong> esophagus,<br />

dehydration, and weight loss.<br />

S: Subjective<br />

The patient may <strong>com</strong>plain <strong>of</strong> difficulty swallowing,<br />

a feeling <strong>of</strong> something being “stuck in <strong>the</strong> throat,”<br />

retrosternal pain when eating, “hiccups,” indigestion<br />

(“heartburn”), acid reflux, nausea, vomiting, or<br />

abdominal pain.<br />

History<br />

The history should include <strong>the</strong> following:<br />

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♦<br />

♦<br />

♦<br />

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♦<br />

♦<br />

♦<br />

Medications (prescription and over-<strong>the</strong>-counter) and<br />

herbal supplements, current and past<br />

Concurrent gastrointestinal (GI) symptoms, such as<br />

abdominal pain or diarrhea<br />

Recent dietary history<br />

Location and characteristics <strong>of</strong> pain (diffuse or focal)<br />

Oral thrush<br />

Aphthous ulcers<br />

Cytomegalovirus (CMV)<br />

Candida esophagitis<br />

GERD<br />

Hiatal hernia<br />

O: Objective<br />

Section 5—Complaint-Specific Workups | 5–13<br />

Include <strong>the</strong> following in <strong>the</strong> physical examination:<br />

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♦<br />

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♦<br />

Measure vital signs (temperature may be elevated<br />

with certain infections, such as CMV, but not<br />

with herpes simplex virus [HSV], candidiasis, or<br />

idiopathic ulcers).<br />

Record weight (and <strong>com</strong>pare with previous weights).<br />

Assess <strong>for</strong> oral candidiasis, lesions, and masses.<br />

Examine optic fundi to evaluate <strong>for</strong> CMV retinitis<br />

(in patients with CD4 counts <strong>of</strong>

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