Clinical Manual for Management of the HIV-Infected ... - myCME.com

Patient Education
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Histoplasmosis is not transmitted from person to
person, so isolation is not necessary.
Patients should take all of their medications exactly
as prescribed by their health care providers.
Even with maintenance therapy, relapses can occur.
Patients should call their providers immediately if
symptoms worsen.
Itraconazole and fluconazole may cause birth defects.
Women who are taking either of these medicines
should avoid pregnancy. In addition, itraconazole
interacts with some other medications; patients
should tell their providers if they begin any other
new medicines while taking itraconazole.
References
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Section 6—Disease-Specific Treatment | 6–53
Centers for Disease Control and Prevention,
National Institutes of Health, HIV Medicine
Association/Infectious Diseases Society of America.
Treating Opportunistic Infections Among HIV-Infected
Adults and Adolescents. MMWR Recomm Rep.
2004 Dec 17; 53(RR15);1-112. Available online
at aidsinfo.nih.gov/Guidelines/GuidelineDetail.
aspx?GuidelineID=14. Accessed May 19, 2006.
Deepe GS Jr. Histoplasma Capsulatum. In: Mandell
G, Bennett JE, Dolin R, eds. Principles and Practice
of Infectious Diseases, 6th ed. Philadelphia: Elsevier;
2005:3012-26.
Goldman M, Zackin R, Fichtenbaum CJ, et al.
Safety of discontinuation of maintenance therapy for
disseminated histoplasmosis after immunologic response
to antiretroviral therapy. Clin Infect Dis. 2004 May
15;38(10):1485-9.
U.S. Public Health Service, Infectious Diseases
Society of America. 2002 Guidelines for preventing
opportunistic infections among HIV-infected persons.
MMWR Recomm Rep. 2002 Jun 14;51(RR08);1-
46. Available online at aidsinfo.nih.gov/Guidelines/.
Accessed May 19, 2006.
Wheat J. Histoplasmosis. In: Dolin R, Masur H,
Saag M, eds. AIDS Therapy, 2nd ed. Philadelphia:
Churchill Livingstone; 2003:511-521.
Wheat J, Sarosi G, McKinsey D, et al. Practice
guidelines for the management of patients with
histoplasmosis. Infectious Diseases Society of
America. Clin Infect Dis. 2000 Apr;30(4):688-95.