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Clinical Manual for Management of the HIV-Infected ... - myCME.com

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5–42 | <strong>Clinical</strong> <strong>Manual</strong> <strong>for</strong> <strong>Management</strong> <strong>of</strong> <strong>the</strong> <strong>HIV</strong>-<strong>Infected</strong> Adult/2006<br />

A: Assessment<br />

The differential diagnosis <strong>of</strong> pulmonary symptoms is<br />

broad (Table 1). Both <strong>HIV</strong>-related and <strong>HIV</strong>-unrelated<br />

causes should be considered; <strong>the</strong> patient’s risk <strong>of</strong> <strong>HIV</strong>related<br />

causes is strongly influenced by <strong>the</strong> CD4 count.<br />

More than 1 cause <strong>of</strong> symptoms may be present.<br />

Table 1. Partial Differential Diagnosis <strong>of</strong> Pulmonary Symptoms<br />

CD4 Cell Count Possible Cause<br />

Any Count • Upper respiratory tract illness<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

•<br />

Upper respiratory tract infection (URI)<br />

Sinusitis<br />

Pharyngitis<br />

Acute or chronic bronchitis<br />

Bacterial pneumonia<br />

TB<br />

Influenza<br />

Chronic obstructive pulmonary disease<br />

Reactive airway disease, asthma<br />

Non-Hodgkin lymphoma<br />

Pulmonary embolus<br />

Congestive heart failure<br />

Pulmonary hypertension<br />

Pneumothorax<br />

Bronchogenic carcinoma<br />

Anemia<br />

Gastroesophageal reflux (may cause cough)<br />

Lactic acidosis<br />

Medication adverse effect<br />

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