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Clinical Manual for Management of the HIV-Infected ... - myCME.com

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Headache<br />

Background<br />

Headache may have many causes in <strong>HIV</strong>-infected<br />

persons, particularly those with low CD4 counts.<br />

Possible causes include infections (opportunistic and<br />

o<strong>the</strong>r) and central nervous system malignancies, <strong>HIV</strong>related<br />

systemic illnesses, and medication toxicity. In<br />

addition, <strong>of</strong> course, headache may be caused by any <strong>of</strong><br />

<strong>the</strong> processes that cause headaches in <strong>HIV</strong>-uninfected<br />

individuals. New or severe headache should be evaluated<br />

carefully.<br />

S: Subjective<br />

The patient <strong>com</strong>plains <strong>of</strong> a new type <strong>of</strong> headache.<br />

Determine <strong>the</strong> following during <strong>the</strong> history:<br />

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History <strong>of</strong> headaches or migraines<br />

Characteristics <strong>of</strong> <strong>the</strong> headache (location, quality <strong>of</strong><br />

pain, timing, duration, etc)<br />

Recent head trauma<br />

Allergies<br />

History <strong>of</strong> sinusitis<br />

Fevers<br />

Visual changes<br />

Dizziness, vertigo, nausea<br />

Mental status changes<br />

Seizures<br />

Focal or o<strong>the</strong>r neurologic symptoms (see chapter<br />

Neurologic Symptoms)<br />

New rashes or ulcerations<br />

O<strong>the</strong>r symptoms<br />

Usual versus recent caffeine intake<br />

New medications (eg, zidovudine)<br />

Relief <strong>of</strong> headache by any medication<br />

Unprotected sex, new sex partner<br />

O: Objective<br />

Section 5—Complaint-Specific Workups | 5–27<br />

Per<strong>for</strong>m a physical examination as follows:<br />

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Check vital signs. Look <strong>for</strong> fever, orthostasis, and<br />

hypertension.<br />

Examine <strong>the</strong> head and neck <strong>for</strong> trauma, sinus<br />

tenderness, and neck mobility; check lymph nodes.<br />

Check <strong>the</strong> eyes, including funduscopic examination,<br />

<strong>for</strong> lesions or papilledema.<br />

Look <strong>for</strong> oral lesions, dental abscess, thrush, and<br />

pharyngeal drainage.<br />

Examine <strong>the</strong> lungs <strong>for</strong> abnormal sounds.<br />

Check <strong>the</strong> skin, including palms and soles, <strong>for</strong> rashes<br />

or lesions.<br />

Per<strong>for</strong>m a <strong>com</strong>plete neurologic examination,<br />

including mental status examination.<br />

Review recent CD4 measurements, if available,<br />

to determine <strong>the</strong> patient’s risk <strong>for</strong> opportunistic<br />

illnesses as a cause <strong>of</strong> headache.<br />

A: Assessment<br />

A partial differential diagnosis includes <strong>the</strong> following:<br />

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Cryptococcal meningitis<br />

Neurosyphilis<br />

Tuberculous meningitis; o<strong>the</strong>r meningitis<br />

Progressive multifocal leukoencephalopathy (PML)<br />

Toxoplasmic encephalitis<br />

Cytomegalovirus (CMV) meningoencephalitis or<br />

retinitis<br />

O<strong>the</strong>r encephalitis<br />

Central nervous system lymphoma<br />

Systemic infection<br />

Sinusitis<br />

Anemia<br />

Fever<br />

Depression, anxiety disorder<br />

Medication adverse effect<br />

Stress or tension headache

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