Clinical Manual for Management of the HIV-Infected ... - myCME.com
Clinical Manual for Management of the HIV-Infected ... - myCME.com
Clinical Manual for Management of the HIV-Infected ... - myCME.com
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Genitals/Rectum<br />
• Inspect <strong>the</strong> genitalia and perirectal area; note lesions, warts, etc.<br />
• Culture discharges, ulcerative lesions, vesicles, and crusted lesions<br />
<strong>for</strong> herpes simplex virus, chancroid, chlamydia, and/or gonorrhea<br />
(GC), as appropriate, and send an RPR (rapid plasma reagin) or VDRL<br />
(Venereal Disease Research Laboratory) test.<br />
Female Patients<br />
•<br />
•<br />
•<br />
•<br />
•<br />
•<br />
Speculum examination–note any lesions on vaginal walls or cervix.<br />
Obtain a Papanicolaou smear. (Note: Abnormal or inconclusive<br />
Papanicolaou smears require colposcopic follow-up, because<br />
invasive cervical cancer may progress rapidly in women with <strong>HIV</strong>.<br />
See chapter Cervical Dysplasia.)<br />
Obtain endocervical swab <strong>for</strong> GC and chlamydia, and a posterior pool<br />
swab <strong>for</strong> wet mount evaluation <strong>for</strong> trichomoniasis, Candida, and<br />
bacterial vaginosis.<br />
Bimanual exam–note size <strong>of</strong> uterus and ovaries, shape, and any<br />
tenderness or pelvic pain.<br />
Rectal examination <strong>for</strong> anorectal lesions, warts, etc, and evaluation<br />
<strong>of</strong> uterine abnormalities.<br />
Anal Papanicolaou smear.*<br />
Male Patients<br />
•<br />
•<br />
•<br />
•<br />
External genitalia–note whe<strong>the</strong>r male is circumcised; note any<br />
lesions, discharge, o<strong>the</strong>r abnormalities, as above.<br />
Testicular examination <strong>for</strong> masses, tenderness.<br />
Rectal exam—digital examination to evaluate rectal tone,<br />
discharge or tenderness, masses, lesions; prostate exam if<br />
appropriate.<br />
Anal Papanicolaou smear.*<br />
* Anal Papanicolaou smear: Consider this test if follow-up<br />
evaluation <strong>of</strong> abnormal Papanicolaou test results is available.<br />
The suggested approach in <strong>HIV</strong>-infected women and men <strong>for</strong><br />
anal dysplasia screening is similar to <strong>the</strong> cervical Papanicolaou<br />
screening guidelines <strong>for</strong> women: per<strong>for</strong>m anal Papanicolaou<br />
test at initial diagnosis and, if normal, repeat at 6 months. If <strong>the</strong><br />
first 2 anal Papanicolaou smears are normal, repeat annually.<br />
If a Papanicolaou test shows ASCUS (atypical squamous cells<br />
<strong>of</strong> undetermined significance) or SIL (squamous intraepi<strong>the</strong>lial<br />
lesion), refer <strong>for</strong> anal colposcopy and biopsy. (See chapter Anal<br />
Dysplasia.)<br />
Section 1—Testing and Assessment | 1–13<br />
Extremities/ Musculoskeletal<br />
•<br />
•<br />
•<br />
•<br />
•<br />
•<br />
Joints—note any enlargement, swelling, or tenderness.<br />
Muscles—<strong>for</strong> <strong>the</strong> major muscle groups, pay close attention to<br />
muscle bulk (normal or decreased), tenderness, or weakness.<br />
Look <strong>for</strong> evidence <strong>of</strong> peripheral fat atrophy.<br />
Consider measuring baseline arm, thigh, and chest circumferences<br />
<strong>for</strong> later <strong>com</strong>parison.<br />
Note nail changes (clubbing, cyanosis, fungal infections).<br />
Assess <strong>for</strong> pedal or leg edema.<br />
Habitus<br />
• Subcutaneous fat loss (face, extremities, buttocks).<br />
• Central fat accumulation (neck, dorsocervical, breasts, abdomen).<br />
Neurologic<br />
•<br />
•<br />
•<br />
•<br />
•<br />
•<br />
Mental status—including orientation, registration, recent and<br />
remote memory, and ability to calculate (serial subtraction)<br />
Cranial nerves<br />
Peripheral sensory examination should include pinprick,<br />
temperature, and vibratory stimuli.<br />
Extremity strength and gait to discern myopathy, neuropathy, and<br />
cerebellar disease<br />
Fine motor skills such as rapid alternating movements (<strong>of</strong>ten<br />
abnormal in dementia)<br />
Deep tendon and plantar reflexes<br />
Psychiatric<br />
•<br />
•<br />
•<br />
•<br />
•<br />
Patient’s general mood (depressed, anxious, hypertalkative, etc)<br />
Verbal content–answers questions appropriately;<br />
discussion <strong>of</strong> suicide<br />
Inappropriate or unusual behavior, such as extremes <strong>of</strong> denial,<br />
hostility, or <strong>com</strong>pulsiveness<br />
See Neuropsychiatric Disorders section <strong>for</strong> more <strong>com</strong>plete<br />
in<strong>for</strong>mation on <strong>com</strong>mon pathologies.<br />
Emergency situations, such as potential suicide or violence—<br />
refer to crisis mental health services <strong>for</strong> immediate evaluation