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Nobody may keep tobacco or food either in his work clothes or at hisworkplace. Meals should be eaten in appropriate canteens, which should beventilated separately and isolated from the work premises. The workclothing should be specially designed for this use and left at the end ofthe shift. [International Labour Office. Encyclopedia of OccupationalHealth and Safety. Vols. I&II. Geneva, Switzerland: InternationalLabour Office, 1983.2258]**PEER REVIEWED**Evacuation: ... If material leaking (not on fire) consider evacuation fromdown wind area based on amount of material spilled, location and weatherconditions. [Association of American Railroads. Emergency Handling ofHazardous Materials in Surface Transportation. Washington, DC: Associationof American Railroads, Bureau of Explosives, 1994.1109]**PEER REVIEWED**If material is not on fire and not involved in a fire: Keep sparks,flames, and other sources of ignition away. Keep material out of watersources and sewers. Attempt to stop leak without hazard. Use water sprayto knock down vapors. [Association of American Railroads. EmergencyHandling of Hazardous Materials in Surface Transportation. Washington, DC:Association of American Railroads, Bureau of Explosives, 1994.1109]**PEERREVIEWED**PRECAUTIONS FOR "CARCINOGENS": Smoking, drinking, eating, storage of foodor of food & beverage containers or utensils, & the application ofcosmetics should be prohibited in any laboratory. All personnel shouldremove gloves, if worn, after completion of procedures in whichcarcinogens have been used. They should ... wash ... hands, preferablyusing dispensers of liq detergent, & rinse ... thoroughly.Consideration should be given to appropriate methods for cleaning theskin, depending on nature of the contaminant. No standard procedure can berecommended, but the use of organic solvents should be avoided. Safetypipettes should be used for all pipetting. /Chemical Carcinogens/[Montesano, R., H. Bartsch, E.Boyland, G. Della Porta, L. Fishbein, R. A.Griesemer, A.B. Swan, L. Tomatis, and W. Davis (eds.). Handling ChemicalCarcinogens in the Laboratory: Problems of Safety. IARC ScientificPublications No. 33. Lyon, France: International Agency for Research onCancer, 1979.8]**PEER REVIEWED**PRECAUTIONS FOR "CARCINOGENS": In animal laboratory, personnel shouldremove their outdoor clothes & wear protective suits (preferablydisposable, one-piece & close-fitting at ankles & wrists), gloves,hair covering & overshoes. ... clothing should be changed daily but... discarded immediately if obvious contamination occurs ... /also,/workers should shower immediately. In chemical laboratory, gloves &gowns should always be worn ... however, gloves should not be assumed toprovide full protection. Carefully fitted masks or respirators may benecessary when working with particulates or gases, & disposableplastic aprons might provide addnl protection. If gowns are of distinctivecolor, this is a reminder that they should not be worn outside of lab./Chemical Carcinogens/ [Montesano, R., H. Bartsch, E.Boyland, G. DellaPorta, L. Fishbein, R. A. Griesemer, A.B. Swan, L. Tomatis, and W. Davis(eds.). Handling Chemical Carcinogens in the Laboratory: Problems ofSafety. IARC Scientific Publications No. 33. Lyon, France: InternationalAgency for Research on Cancer, 1979.8]**PEER REVIEWED**PRECAUTIONS FOR "CARCINOGENS": ... Operations connected with synth &purification ... should be carried out under well-ventilated hood.
Analytical procedures ... should be carried out with care & vaporsevolved during ... procedures should be removed. ... Expert advice shouldbe obtained before existing fume cupboards are used ... & when newfume cupboards are installed. It is desirable that there be means fordecreasing the rate of air extraction, so that carcinogenic powders can behandled without ... powder being blown around the hood. Glove boxes shouldbe kept under negative air pressure. Air changes should be adequate, sothat concn of vapors of volatile carcinogens will not occur. /ChemicalCarcinogens/ [Montesano, R., H. Bartsch, E.Boyland, G. Della Porta, L.Fishbein, R. A. Griesemer, A.B. Swan, L. Tomatis, and W. Davis (eds.).Handling Chemical Carcinogens in the Laboratory: Problems of Safety. IARCScientific Publications No. 33. Lyon, France: International Agency forResearch on Cancer, 1979.8]**PEER REVIEWED**PRECAUTIONS FOR "CARCINOGENS": Vertical laminar-flow biological safetycabinets may be used for containment of in vitro procedures ... providedthat the exhaust air flow is sufficient to provide an inward air flow atthe face opening of the cabinet, & contaminated air plenums that areunder positive pressure are leak-tight. Horizontal laminar-flow hoods orsafety cabinets, where filtered air is blown across the working areatowards the operator, should never be used ... Each cabinet or fumecupboard to be used ... should be tested before work is begun (eg, withfume bomb) & label fixed to it, giving date of test & avg air-flowmeasured. This test should be repeated periodically & after anystructural changes. /Chemical Carcinogens/ [Montesano, R., H. Bartsch,E.Boyland, G. Della Porta, L. Fishbein, R. A. Griesemer, A.B. Swan, L.Tomatis, and W. Davis (eds.). Handling Chemical Carcinogens in theLaboratory: Problems of Safety. IARC Scientific Publications No. 33. Lyon,France: International Agency for Research on Cancer, 1979.9]**PEERREVIEWED**PRECAUTIONS FOR "CARCINOGENS": Principles that apply to chem or biochemlab also apply to microbiological & cell-culture labs ... Specialconsideration should be given to route of admin. ... Safest method ofadministering volatile carcinogen is by injection of a soln. Admin bytopical application, gavage, or intratracheal instillation should beperformed under hood. If chem will be exhaled, animals should be keptunder hood during this period. Inhalation exposure requires specialequipment. ... unless specifically required, routes of admin other than inthe diet should be used. Mixing of carcinogen in diet should be carriedout in sealed mixers under fume hood, from which the exhaust is fittedwith an efficient particulate filter. Techniques for cleaning mixer &hood should be devised before expt begun. When mixing diets, specialprotective clothing &, possibly, respirators may be required./Chemical Carcinogens/ [Montesano, R., H. Bartsch, E.Boyland, G. DellaPorta, L. Fishbein, R. A. Griesemer, A.B. Swan, L. Tomatis, and W. Davis(eds.). Handling Chemical Carcinogens in the Laboratory: Problems ofSafety. IARC Scientific Publications No. 33. Lyon, France: InternationalAgency for Research on Cancer, 1979.9]**PEER REVIEWED**PRECAUTIONS FOR "CARCINOGENS": When ... admin in diet or applied to skin,animals should be kept in cages with solid bottoms & sides &fitted with a filter top. When volatile carcinogens are given, filter topsshould not be used. Cages which have been used to house animals thatreceived carcinogens should be decontaminated. Cage-cleaning facilitiesshould be installed in area in which carcinogens are being used, to avoidmoving of ... contaminated /cages/. It is difficult to ensure that cages
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The following information was gener
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... ANOREXIA, ... ALLERGIC DERMATIT
Page 7 and 8:
cancer. Many of the workers had bee
Page 9 and 10:
personnel records of nine chemical
Page 11 and 12: worker consumed more than a very lo
Page 13 and 14: (1): 37-45 (1991)]**PEER REVIEWED**
Page 15 and 16: workers to the vinyl chloride monom
Page 17 and 18: skin cancer could bear some relatio
Page 19 and 20: N-5'-alkylpurine (AP) endonucleases
Page 21 and 22: Agency for Research on Cancer, 1979
Page 23 and 24: LIFE SUPPORT:oThis overview assumes
Page 25 and 26: exposure circumstance entails expos
Page 27 and 28: for carcinogenicity in human epidem
Page 29 and 30: Risk of Chemicals to Man. Geneva: W
Page 31 and 32: exposure groups did not differ from
Page 33 and 34: in vivo. [Barbin A; IARC 150: 303-1
Page 35 and 36: developed to localize the promutage
Page 37 and 38: WORKERS. THE VALUE OBTAINED WERE IN
Page 39 and 40: (2): 259 (1977)]**PEER REVIEWED**Af
Page 41 and 42: y 1 mg/cu m of either /cmpd/ separa
Page 43 and 44: (1980) as cited in USEPA; Health an
Page 45 and 46: (1975)]**PEER REVIEWED**ENVIRONMENT
Page 47 and 48: The Koc of vinyl chloride is estima
Page 49 and 50: REVIEWED**SEDIMENT/SOIL CONCENTRATI
Page 51 and 52: Fugitive emission sources; (3) Leak
Page 53 and 54: BOILING POINT:-13.3 deg C [Lide, D.
Page 55 and 56: Washington, D.C: U.S. Government Pr
Page 57 and 58: Reactivity: 2. 2= This degree inclu
Page 59 and 60: Vinyl chloride/ decomposes on burni
Page 61: available./ ... Safety pipettes sho
Page 65 and 66: equipment. [Association of American
Page 67 and 68: done without undue risk. Use water
Page 69 and 70: Fishbein, R. A. Griesemer, A.B. Swa
Page 71 and 72: 673-6121; Production site: Geismar,
Page 73 and 74: 91% FOR POLYVINYL CHLORIDE [Kavaler
Page 75 and 76: halogen-specific detector for the a
Page 77 and 78: phthalate esters, detectable levels
Page 79 and 80: USEPA; Drinking water Criteria Docu
Page 81 and 82: ADMINISTRATIVE INFORMATION:HAZARDOU
Page 83: Field Update on 01/15/1990, 1 field
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