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SPECIAL REPORTS:USEPA; Ambient Water Quality Criteria Doc: Vinyl Chloride (1980) EPA440/5-80-078.Environment Canada; Tech Info for Problem Spills: Vinyl Chloride (Draft)(1981).A REVIEW CONTAINING OVER 100 REFERENCES OF SAMPLING AND ANALYTICAL METHODSFOR VINYL CHLORIDE IN WORKPLACE ATMOSPHERE, AMBIENT AIR, WATER, FOOD,CIGARETTE SMOKE, AND POLYVINYL CHLORIDE. EGAN H ET AL, EDS, ENVIRONMENTALCARCINOGENS SELECTED METHODS OF ANALYSIS VOL 2, VINYL CHLORIDE (IARCSCIENTIFIC PUBLICATIONS NUMBER 22) LYON (1979).USEPA; Report on the Activities and Findings of the Vinyl Chloride TaskForce (1974) EPA 560/4-74-001.Malhotra VP, Saroop UK; Toxicity and Vinyl Chloride. Pop Plast 29 (2):17-20 (1984). The occupational hazard and toxicity exposure of vinylchloride are reviewed ... /including the occupational/ health hazard fromvinyl chloride exposure and toxicity of vinyl chloride monomer.Duverger M et al; Metabolic Activation and Mutagenicity of 4 VinylMonomers (Vinyl chloride, Styrene, Acrylonitrile, Butadiene). Toxicol EurRes 3 (3): 131-40 (1981). A review with 130 refs on the metabolicactivation and mutagenicity of vinyl chloride, styrene, acrylonitrile, andbutadiene.Jedrychowski R, Chmielnicka J; Med Pr 36 (1): 31-41 (1985). Evaluation ofthe toxicity of vinyl chloride based on metabolism /is discussed/ .../including/ review /of/ absorption, distribution, occupational exposure.Wogan GN, Gorelick NJ; Chemical and Biochemical Dosimetry of Exposure toGenotoxic Chemicals. Environ Health Perspect 62: 5-18 (1985).Sharma RP; Immunol Consid Toxicol 1: 79-88 (1981). A review with 17 refson the immunol responses to vinyl chloride and other industrial chemicals.Suzuki T, Himeno S; Saishin Igaku 37 (12): 2355-61 (1982). A review with47 refs on dominant lethal mutations from vinyl chloride.Kilbey BJ; Environ Sci Res 24 (Comp Chem Mutagen): 857-81 (1981). A reviewwith 75 refs on the comparative mutagenicity of aflatoxin B1 and vinylchloride.Nauman CH, Grant WF; Environ Sci Res 24 (Comp Chem Mutagen): 329-38(1981). A review with 27 refs on the mutagenicity of ethylmethanesulfonate, mitomycin C, and vinyl chloride in the Tradescantia testsystems.DHHS/ATSDR; Toxicological Profile for Vinyl Chloride (Update) TP-92/20(1993)USEPA; Health and Environmental Effects Profile for Chloroethene (1985)ECAO-CIN-P155.
USEPA; Drinking water Criteria Document for Vinyl Chloride (1986)PB86-118320.U.S. Department of Health & Human Services/National ToxicologyProgram; Tenth Report on Carcinogens. National Institutes ofEnvironmental Health Sciences. The Report on Carcinogens is aninformational scientific and public health document that identifies anddiscusses substances (including agents, mixtures, or exposurecircumstances) that may pose a carcinogenic hazard to human health. VinylChloride (75-01-4) was listed in the First Annual Report on Carcinogens(1980) as known to be a human carcinogen . [ ]U.S. Dept of Health & Human Services, Public Health Service, ATSDR;Toxicological profile for vinyl chloride: Update.Dogliotti E et al; Recent Results Cancer Res 154: 97-124 (1998). Mutationspectra resulting from carcinogenic exposure: from model systems tocancer-related genes.Legator MS; Ann N Y Acad Sci 837: 170-175 (1997). Underestimating risk forthree important human carcinogens: vinyl chloride, benzene, and butadiene.McLaughlin JK et al; J Epidemiol Biostat 4 (4): 253-275 (1999). A criticalreview of the epidemiologic literature on health effects of occupationalexposure to vinyl chloride.Ostrowske SR et al; Toxicology and Industrial Health 15 (7): 602-644(1999). Agency for Toxic Substances and Disease Registry's 1997 prioritylist of hazardous substances. Latent effects carcinogenesis,neurotoxicology, and developmental deficits in humans and animals.SYNONYMS AND IDENTIFIERS:SYNONYMS:CHLORETHENE **PEER REVIEWED**CHLORETHYLENE **PEER REVIEWED**CHLOROETHENE **PEER REVIEWED**CHLOROETHYLENE **PEER REVIEWED**CHLORURE DE VINYLE (FRENCH) **PEER REVIEWED**CLORURO DI VINILE (ITALIAN) **PEER REVIEWED**Ethene, chloro- **PEER REVIEWED**ETHYLENE, CHLORO- **PEER REVIEWED**ETHYLENE MONOCHLORIDE **PEER REVIEWED**MONOCHLOROETHENE **PEER REVIEWED**MONOCHLOROETHYLENE **PEER REVIEWED**
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The following information was gener
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... ANOREXIA, ... ALLERGIC DERMATIT
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cancer. Many of the workers had bee
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personnel records of nine chemical
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worker consumed more than a very lo
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(1): 37-45 (1991)]**PEER REVIEWED**
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workers to the vinyl chloride monom
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skin cancer could bear some relatio
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N-5'-alkylpurine (AP) endonucleases
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Agency for Research on Cancer, 1979
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LIFE SUPPORT:oThis overview assumes
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exposure circumstance entails expos
Page 27 and 28: for carcinogenicity in human epidem
Page 29 and 30: Risk of Chemicals to Man. Geneva: W
Page 31 and 32: exposure groups did not differ from
Page 33 and 34: in vivo. [Barbin A; IARC 150: 303-1
Page 35 and 36: developed to localize the promutage
Page 37 and 38: WORKERS. THE VALUE OBTAINED WERE IN
Page 39 and 40: (2): 259 (1977)]**PEER REVIEWED**Af
Page 41 and 42: y 1 mg/cu m of either /cmpd/ separa
Page 43 and 44: (1980) as cited in USEPA; Health an
Page 45 and 46: (1975)]**PEER REVIEWED**ENVIRONMENT
Page 47 and 48: The Koc of vinyl chloride is estima
Page 49 and 50: REVIEWED**SEDIMENT/SOIL CONCENTRATI
Page 51 and 52: Fugitive emission sources; (3) Leak
Page 53 and 54: BOILING POINT:-13.3 deg C [Lide, D.
Page 55 and 56: Washington, D.C: U.S. Government Pr
Page 57 and 58: Reactivity: 2. 2= This degree inclu
Page 59 and 60: Vinyl chloride/ decomposes on burni
Page 61 and 62: available./ ... Safety pipettes sho
Page 63 and 64: Analytical procedures ... should be
Page 65 and 66: equipment. [Association of American
Page 67 and 68: done without undue risk. Use water
Page 69 and 70: Fishbein, R. A. Griesemer, A.B. Swa
Page 71 and 72: 673-6121; Production site: Geismar,
Page 73 and 74: 91% FOR POLYVINYL CHLORIDE [Kavaler
Page 75 and 76: halogen-specific detector for the a
Page 77: phthalate esters, detectable levels
Page 81 and 82: ADMINISTRATIVE INFORMATION:HAZARDOU
Page 83: Field Update on 01/15/1990, 1 field
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