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are decontaminated, & monitoring methods are necessary. Situations mayexist in which the use of disposable cages should be recommended,depending on type & amt of carcinogen & efficiency with which itcan be removed. /Chemical Carcinogens/ [Montesano, R., H. Bartsch,E.Boyland, G. Della Porta, L. Fishbein, R. A. Griesemer, A.B. Swan, L.Tomatis, and W. Davis (eds.). Handling Chemical Carcinogens in theLaboratory: Problems of Safety. IARC Scientific Publications No. 33. Lyon,France: International Agency for Research on Cancer, 1979.10]**PEERREVIEWED**PRECAUTIONS FOR "CARCINOGENS": To eliminate risk that ... contamination inlab could build up during conduct of expt, periodic checks should becarried out on lab atmospheres, surfaces, such as walls, floors &benches, & ... interior of fume hoods & airducts. As well asregular monitoring, check must be carried out after cleaning-up ofspillage. Sensitive methods are required when testing lab atmospheres forchem such as nitrosamines. Methods ... should ... where possible, besimple & sensitive. ... /Chemical Carcinogens/ [Montesano, R., H.Bartsch, E.Boyland, G. Della Porta, L. Fishbein, R. A. Griesemer, A.B.Swan, L. Tomatis, and W. Davis (eds.). Handling Chemical Carcinogens inthe Laboratory: Problems of Safety. IARC Scientific Publications No. 33.Lyon, France: International Agency for Research on Cancer, 1979.10]**PEERREVIEWED**PRECAUTIONS FOR "CARCINOGENS": Rooms in which obvious contamination hasoccurred, such as spillage, should be decontaminated by lab personnelengaged in expt. Design of expt should ... avoid contamination ofpermanent equipment. ... Procedures should ensure that maintenance workersare not exposed to carcinogens. ... Particular care should be taken toavoid contamination of drains or ventilation ducts. In cleaning labs,procedures should be used which do not produce aerosols or dispersal ofdust, ie, wet mop or vacuum cleaner equipped with high-efficiencyparticulate filter on exhaust, which are avail commercially, should beused. Sweeping, brushing & use of dry dusters or mops should beprohibited. Grossly contaminated cleaning materials should not be re-used... If gowns or towels are contaminated, they should not be sent tolaundry, but ... decontaminated or burnt, to avoid any hazard to laundrypersonnel. /Chemical Carcinogens/ [Montesano, R., H. Bartsch, E.Boyland,G. Della Porta, L. Fishbein, R. A. Griesemer, A.B. Swan, L. Tomatis, andW. Davis (eds.). Handling Chemical Carcinogens in the Laboratory: Problemsof Safety. IARC Scientific Publications No. 33. Lyon, France:International Agency for Research on Cancer, 1979.10]**PEER REVIEWED**PRECAUTIONS FOR "CARCINOGENS": Doors leading into areas where carcinogensare used ... should be marked distinctively with appropriate labels.Access ... limited to persons involved in expt. ... A prominentlydisplayed notice should give the name of the Scientific Investigator orother person who can advise in an emergency & who can inform others(such as firemen) on the handling of carcinogenic substances. /ChemicalCarcinogens/ [Montesano, R., H. Bartsch, E.Boyland, G. Della Porta, L.Fishbein, R. A. Griesemer, A.B. Swan, L. Tomatis, and W. Davis (eds.).Handling Chemical Carcinogens in the Laboratory: Problems of Safety. IARCScientific Publications No. 33. Lyon, France: International Agency forResearch on Cancer, 1979.11]**PEER REVIEWED**Personnel protection: Avoid breathing vapors. Keep up wind. ... Do nothandle broken packages unless wearing appropriate personal protective
equipment. [Association of American Railroads. Emergency Handling ofHazardous Materials in Surface Transportation. Washington, DC: Associationof American Railroads, Bureau of Explosives, 1994.1109]**PEER REVIEWED**SRP: Contaminated protective clothing should be segregated in such amanner so that there is no direct personal contact by personnel whohandle, dispose, or clean the clothing. Quality assurance to ascertain thecompleteness of the cleaning procedures should be implemented before thedecontaminated protective clothing is returned for reuse by the workers.**PEER REVIEWED**Work clothing that becomes wet should be immediately removed due to itsflammability hazard. [NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS(NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government PrintingOffice, 1997.331]**PEER REVIEWED**STABILITY/SHELF LIFE:May produce peroxides. [Clayton, G.D., F.E. Clayton (eds.) Patty'sIndustrial Hygiene and Toxicology. Volumes 2A, 2B, 2C, 2D, 2E, 2F:Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc.,1993-1994.4169]**PEER REVIEWED**SHIPMENT METHODS AND REGULATIONS:No person may /transport,/ offer or accept a hazardous material fortransportation in commerce unless that person is registered in conformance... and the hazardous material is properly classed, described, packaged,marked, labeled, and in condition for shipment as required or authorizedby ... /the hazardous materials regulations (49 CFR 171-177)./ [49 CFR171.2 (7/1/2000)]**PEER REVIEWED**The International Air Transport Association (IATA) Dangerous GoodsRegulations are published by the IATA Dangerous Goods Board pursuant toIATA Resolutions 618 and 619 and constitute a manual of industry carrierregulations to be followed by all IATA Member airlines when transportinghazardous materials. [IATA. Dangerous Goods Regulations. 41st Ed.Montreal,Canada and Geneva, Switzerland: International Air Transport Association,Dangerous Goods Regulations, 2000. 234]**PEER REVIEWED**The International Maritime Dangerous Goods Code lays down basic principlesfor transporting hazardous chemicals. Detailed recommendations forindividual substances and a number of recommendations for good practiceare included in the classes dealing with such substances. A general indexof technical names has also been compiled. This index should always beconsulted when attempting to locate the appropriate procedures to be usedwhen shipping any substance or article. [IMDG; International MaritimeDangerous Goods Code; International Maritime Organization p.2186(1998)]**PEER REVIEWED**STORAGE CONDITIONS:STORE IN COOL, DRY, WELL-VENTILATED LOCATION. SEPARATE FROM OXIDIZINGMATERIALS. [Fire Protection Guide to Hazardous Materials. 12 ed. Quincy,MA: National Fire Protection Association, 1997. 49-136]**PEER REVIEWED**Containers of vinyl chloride shall be legibly labeled either: VINYLCHLORIDE: EXTREMELY FLAMMABLE GAS UNDER PRESSURE: CANCER SUSPECT AGENT or... with the additional legend CANCER-SUSPECT AGENT applied near the labelor placard. [29 CFR 1910.1017 (7/1/90]**PEER REVIEWED**
Page 1:
The following information was gener
Page 5 and 6:
... ANOREXIA, ... ALLERGIC DERMATIT
Page 7 and 8:
cancer. Many of the workers had bee
Page 9 and 10:
personnel records of nine chemical
Page 11 and 12:
worker consumed more than a very lo
Page 13 and 14: (1): 37-45 (1991)]**PEER REVIEWED**
Page 15 and 16: workers to the vinyl chloride monom
Page 17 and 18: skin cancer could bear some relatio
Page 19 and 20: N-5'-alkylpurine (AP) endonucleases
Page 21 and 22: Agency for Research on Cancer, 1979
Page 23 and 24: LIFE SUPPORT:oThis overview assumes
Page 25 and 26: exposure circumstance entails expos
Page 27 and 28: for carcinogenicity in human epidem
Page 29 and 30: Risk of Chemicals to Man. Geneva: W
Page 31 and 32: exposure groups did not differ from
Page 33 and 34: in vivo. [Barbin A; IARC 150: 303-1
Page 35 and 36: developed to localize the promutage
Page 37 and 38: WORKERS. THE VALUE OBTAINED WERE IN
Page 39 and 40: (2): 259 (1977)]**PEER REVIEWED**Af
Page 41 and 42: y 1 mg/cu m of either /cmpd/ separa
Page 43 and 44: (1980) as cited in USEPA; Health an
Page 45 and 46: (1975)]**PEER REVIEWED**ENVIRONMENT
Page 47 and 48: The Koc of vinyl chloride is estima
Page 49 and 50: REVIEWED**SEDIMENT/SOIL CONCENTRATI
Page 51 and 52: Fugitive emission sources; (3) Leak
Page 53 and 54: BOILING POINT:-13.3 deg C [Lide, D.
Page 55 and 56: Washington, D.C: U.S. Government Pr
Page 57 and 58: Reactivity: 2. 2= This degree inclu
Page 59 and 60: Vinyl chloride/ decomposes on burni
Page 61 and 62: available./ ... Safety pipettes sho
Page 63: Analytical procedures ... should be
Page 67 and 68: done without undue risk. Use water
Page 69 and 70: Fishbein, R. A. Griesemer, A.B. Swa
Page 71 and 72: 673-6121; Production site: Geismar,
Page 73 and 74: 91% FOR POLYVINYL CHLORIDE [Kavaler
Page 75 and 76: halogen-specific detector for the a
Page 77 and 78: phthalate esters, detectable levels
Page 79 and 80: USEPA; Drinking water Criteria Docu
Page 81 and 82: ADMINISTRATIVE INFORMATION:HAZARDOU
Page 83: Field Update on 01/15/1990, 1 field
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