th  - 1987 - 51st ENC Conference

WF66
IMMOBILIZED FERRITE pAirri~ 1:'~: 5ELEL'rlVE SPOILING OF A HOMOGENF.OUS B o FIELD AND
ITS APplICATION TO SLrI~A~ C01L $ ~ P Y .
Y. Oeoffrion'. M. Rydw. I. C. P Smith sod H C. J~roU
Division of BiololicaJ Sciences
Nations/Research Council of Csosdt
Ottawa, CANADA KIA 01~
Ferrite pa.,'ticles on • solid support have been used to achieve selective sod
lo~ spoilinj of• homogeneous Bo field. IH ~ imNLini techniques sad 3ip
surface coil studies on phantoms have been used to deLineste the proTde of the loca/ized
perturbation of the Bo field sod to further demonstrste thst in the p~sont sppticstion
the spoifin| effect is Limited to _~ 0,5 cm •ray from the surface of the immobi/o.ed ferrite
particles. AppLication of this spproach to surface coU studies on a,nims/s has shoved that
itvu feasible to discrimiatte between 31p resonsoces originttiaj from tissues near the
body surface ofso soims/from those originttiag from tissues lyinj deeper in the
mmlmml.