th  - 1987 - 51st ENC Conference

Tuesday - AM
NOVEL APPROACHES TO THREE-DIMENSIONAL NMR
C. Griesinger, R. Br~schweiler, O.W. S~rensen
and R.R. Ernst
Laboratorium fur Physikalische Chemie
Eidgen~ssische Technische Hochschule
8092 Z~rich, Switzerland
Extensions of NMR spectroscopy to three dimensions
will be described. Useful 3D techniques can be
obtained by combining building blocks of known 2D
pulse techniques. In order to achieve tolerable
sizes of data matrices and measuring times new
approaches have been developed for the extraction of
restricted volumes of the 3D spectrum.
3D NMR presents considerable potential for NMR
investigations of large biological macromolecules in
solution where overlap of cross peaks is becoming a
limiting factor.