th  - 1987 - 51st ENC Conference

WK46
MULTIPLE-ACQUISITION TWO-DIMENSIONAL HOMONUCLEAR
SHIFT CORRELATION SPECTROSCOPY
Dieter J. Neyerhoff* and Rudi Nunlist*
NMR Center
Department of Chemistry
University of California
Berkeley, Ca. 94720
Two-dimensional homonuclear shift correlation spectroscopy
experiments are very powerful for molecular structure elucidation.
Experiments such as COSY, delayed COSY, relayed COSY and NOESY are
routinely used; in order to get reliable information they often
have to be repeated several times with different parameters.
Pulse sequences and programs will be given which - similar to
the CONOESY experiment* - combine such experiments into a single
pulse sequence. Each dataset obtained this way contains different
information depending on the stage of magnetization at tha time of
acquisition.
Application of these pulse-sequences eliminate the need of
repeating entire experiments with slightly different parameters
and thus reduce experimental time and operator interference
significantly.
Experimental data will be presented to illustrate the power
of multiple-acquisition 2D pulse experiments.
I. Haasnot, C. A. G.; van de Ven, F. J. M.; Hilbers, C. W. J.
Magn. Res. 1984, 56, 343-349. Gurevich, A. Z.; Barsukov, I.
L.; Arseniev, A. S.; Bystrov, V. F. J. Magn. Res. 1984, 56,
471-478.