Acute Leukemias - Republican Scientific Medical Library

a 16.4 · Therapeutic Approaches 205
Table 16.1. Clinical characteristics of lymphoblastic lymphoma
Bernasconi, Santini, Morel, Zinzani, Bouabdallah, Sweetenham, Hoelzer, Thomas,
et al. [12] et al. [13] et al. [14] et al. [15] et al. [16] et al. [17] et al. [11] et al. [18]
Year 1990 1991 1992 1996 1998 1997 2002 2004
N 31 40 54 53 62 95 45 33
Age 25 (15–64) 22 (15–51) 34 (15–76) 37 (15–78) 35 (14–70) 25 (>14) 25 (15–61) 28 (17–59)
Male gender 61% 62% 65% 74% 75% 69% 73% 82%
B-symptoms 16% n.r. 48% 23% n.r. 34% 27% 30%
Stage III/IV 68% 95% 58% 66% 73% 70% 73% 70%
Med. involvement 61% 85% 61% 57% 63% n.r. 91% 70%
CNS involvement 10% 8% 2% 4% 6% n.r. 0% 9%
Subtype T-cell n.r. 77% 85% 62% n.r. 68% 100% 79%
Subtype B-cell n.r. 17% 2% 38% n.r. 32% 0% 18%
LDH increased n.r. n.r. 62% 60% 79% 48% 84% 24%