Acute Leukemias - Republican Scientific Medical Library

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294 Subject Index single-gene mutations 82 sinusoidal obstructive syndrome (SOS) 64 Smad3 101 smears 28 socioeconomic status 82 Southern blotting 32 spinal irradiation 271 splenomegaly 110 Src kinases 180 stem cell leukemia 179 stem cell transplantation 150, 171 – LALA study group 150 stem cell transplantation (SCT) 140, 147, 204, 229 stem cells 222 – bone marrow 222 – peripheral blood 222 sudan black (SB) stain 29 sulfonylhydrazine alkylating agent 65 SVC syndrome 284 SWOG 219, 234 5q-syndrome and refractory anemia 27 T T cell receptor (TCR) 152 T-cell 224 – depletion 224 T-cell receptor (TCR) 98 T-cell receptor (TCR) gene 250 T-cell receptors 126 T-lymphocytes 224 TBI 232 TBI, see total body irradiation 220 TCR gene rearrangements 256 TEL-AML1 fusion gene 250 teniposide 270 terminal deoxynucleotidyl transferase (TdT) 263 terminal deoxynucleotidyltransferase (TdT) 122 tetrasomy 21 100 thiopurine methyltransferase (TPMT) 243 thiopurine-S-methyltransferase (TPMT) 102 thrombocytopenia 77, 138, 143, 192 thymidylate synthase (TS) 243 thymoma cells 115 TLX1 gene expression 102 TNF-receptor family 265 tobacco smoke 88 topoisomerase II 36 topoisomerase II inhibitors 52–53 total body irradiation 278 total body irradiation (TBI) 216, 220, 230 total leukemia mortality 80 TPMT, see thiopurine-S-methyltransferase 102 transplant related mortality (TRM) 209, 220 transplant-related mortality (TRM) 231–232 TRD, see treatment-related death 2 TRD, treatment-related death – therapy 2 – treatment 2 treatment-related death (TRD) 2 trichloroethylene 87 triple intrathecal chemotherapy (TIC) 267 trisomy 8 100–101, 182 trithorax 35 TRM, see transplant related mortality 220 tumor necrosis factor a (TNF) 265 tyrosine kinase 38 tyrosine-kinase (TK) 171 U UCB, see umbilical cord blood 222 umbilical cord blood (UCB) 222 urate oxidase 193 urate oxidase (UO) 282 uric acid formation 282 urine alkalinization 281 V veno-occlusive disease (VOD) 64 vincristine 133, 137, 142, 146, 148, 153, 162, 192, 238, 270, 275 – liposomal 238–239 vincritine 101 vindesine 153 W white blood cell index 4 Wright-Giemsa staining 28 X xanthine oxidase 281 Z zorubicin 147, 217, 231
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E.H. Estey · S.H. Faderl · H. M.
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E. H. Estey Department of Leukemia
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VI Table of Contents 14 Philadelphi
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VIII Contributors S. H. Faderl Depa
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X Contributors D. Wartenberg Depart
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Therapy of AML Elihu Estey Contents
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a 1.2 · Standard Therapy 3 Table 1
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a 1.2 · Standard Therapy 5 Table 1
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a 1.2 · Standard Therapy 7 tween G
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a 1.2 · Standard Therapy 9 Fig. 1.
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a 1.2 · Standard Therapy 11 of tre
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a 1.2 · Standard Therapy 13 Table
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a 1.2 · Standard Therapy 15 permit
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a References 17 19. Care RS, Valk P
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a References 19 6-thioguanine in th
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Acute Myeloid Leukemia: Epidemiolog
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a 3.1 · Epidemiology 49 3.1.4 Gend
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a 3.2 · Etiology 51 part of the in
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a 3.2 · Etiology 53 for the develo
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a References 55 38. Crane MM, Stom
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Relapsed and Refractory Acute Myelo
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a 4.2 · Prognostic Factors in Pati
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a 4.3 · Treatment of Relapsed and
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a 4.4 · Hematopoietic Stem Cell Tr
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a 4.6 · Gemtuzumab Ozogamicin 65 T
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a 4.7 · Relapsed and Refractory Ac
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a 4.7 · Relapsed and Refractory Ac
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a References 71 The ability of immu
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a References 73 39. Vogler WR, McCa
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a References 75 95. Sievers EL, Lar
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Part II - Acute Lymphoblastic Leuke
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78 Chapter 5 · Acute Lymphoblastic
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Molecular Biology and Genetics Meir
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a 6.3 · Structural Aberrations 97
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a 6.3 · Structural Aberrations 99
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a 6.5 · Molecular Aberrations 101
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a References 103 clear that homozyg
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a References 105 53. Chim CS, Tam C
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a References 107 122. Lennard L, Li
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Diagnosis of Acute Lymphoblastic Le
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a 8.3 · Cytochemistry and Immunoph
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a 8.5 · Cytogenetic and Molecular
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a 8.5 · Cytogenetic and Molecular
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a References 127 including the reti
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a References 129 47. Kita K, Shirak
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Acute Lymphoblastic Leukemia: Clini
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a 7.3 · Diagnosis 111 or neoplasti
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a 7.3 · Diagnosis 113 Fig. 7.2. Hi
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a 7.3 · Diagnosis 115 The vast maj
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a References 117 dren: Biologic bas
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General Approach to the Therapy of
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a 9.3 · New Agents 133 dose methot
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a References 135 4. Gökbuget N, Ho
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138 Chapter 10 · Recent Clinical T
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146 Chapter 11 · Conventional Ther
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ALL Therapy: Review of the MD Ander
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a 12.2 · The Hyper-CVAD Regimen in
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a 12.3 · Subset-Specific Approache
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Treatment of Adult ALL According to
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a 13.2 · Therapy for Younger (15-6
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a 13.3 · Therapy of Ph/BCR-ABL-Pos
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a 13.5 · Prognostic Factors 173 13
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a References 175 Only patients with
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Philadelphia Chromosome-Positive Ac
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a 14.2 · Molecular Biology of the
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a 14.3 · Treatment of Ph+ ALL 181
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a 14.4 · Hematopoietic Stem Cell T
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a References 185 2. Kurzrock R, Sht
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a References 187 56. Mori T, Manabe
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a References 189 acute lymphoblasti
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192 Chapter 15 · Burkitt’s Acute
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204 Chapter 16 · Treatment of Lymp
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216 Chapter 17 · The Role of Allog
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230 Chapter 18 · The Role of Autol
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238 Chapter 19 · Novel Therapies i
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240 Chapter 19 · Novel Therapies i
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Page 261 and 262: Emergencies in Acute Lymphoblastic
Page 263 and 264: a 23.5 · Hyperleukocytosis 283 LA
Page 265 and 266: a 23.9 · Neurological Complication
Page 267 and 268: a References 287 29. Hingorani AD,
Page 269 and 270: Subject Index A aberrant methylatio
Page 271 and 272: a Subject Index 291 CREB, see enhan
Page 273: a Subject Index 293 MUD, see matche
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