Acute Leukemias - Republican Scientific Medical Library

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104 Chapter 6 · Molecular Biology and Genetics man Multicenter Trial Group and confirmed polymerase chain reaction analysis. Blood 99(5):1536–543 21. Radich J, Gehly G, Lee A, et al. (1997) Detection of bcr-abl transcripts in Philadelphia chromosome-positive acute lymphoblastic leukemia after marrow transplantation. Blood 89(7):2602–2609 22. Thomas DA, Faderl S, Cortes J, et al. (2004) Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood 103(12):4396–4407 23. Preti HA, O’Brien S, Giralt S, Beran M, Pierce S, Kantarjian HM (1994) Philadelphia-chromosome-positive adult acute lymphocytic leukemia: Characteristics, treatment results, and prognosis in 41 patients. Am J Med 97(1):60–65 24. Thomas X, Thiebaut A, Olteanu N, et al. (1998) Philadelphia chromosome positive adult acute lymphoblastic leukemia: Characteristics, prognostic factors and treatment outcome. Hematol Cell Ther 40(3):119–128 25. 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Hilden JM, Chen CS, Moore R, Frestedt J, Kersey JH (1993) Heterogeneity in MLL/AF-4 fusion messenger RNA detected by the polymerase chain reaction in t(4;11) acute leukemia. Cancer Res 53(17):3853–3856 41. Biondi A, Rambaldi A, Rossi V, et al. (1993) Detection of ALL-1/AF4 fusion transcript by reverse transcription-polymerase chain reaction for diagnosis and monitoring of acute leukemias with the t(4;11) translocation. Blood 82(10):2943–2947 42. Yamamoto K, Seto M, Iida S, et al. (1994) A reverse transcriptasepolymerase chain reaction detects heterogeneous chimeric mRNAs in leukemias with 11q23 abnormalities. Blood 83(10): 2912–2921 43. Griesinger F, Elfers H, Ludwig WD, et al. (1994) Detection of HRX- FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11). Leukemia 8(4):542–548 44. Uckun FM, Herman-Hatten K, Crotty ML, et al. 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(2000) Monosomy 20 as a pointer to dicentric (9;20) in acute lymphoblastic leukemia. Leukemia 14(2):241–246 59. Strehl S, Konig M, Dworzak MN, Kalwak K, Haas OA (2003) PAX5/ ETV6 fusion defines cytogenetic entity dic(9;12)(p13;p13). Leukemia 17(6):1121–1123 60. Aissani B, Bonan C, Baccichet A, Sinnett D (1999) Childhood acute lymphoblastic leukemia: Is there a tumor suppressor gene in chromosome 12p12.3? Leuk Lymphoma 34(3–4):231–239 61. Montpetit A, Larose J, Boily G, Langlois S, Trudel N, Sinnett D (2004) Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia. Leukemia 18(9):1499–1504 62. Aguiar RC, Sohal J, van Rhee F, et al. (1996) TEL-AML1 fusion in acute lymphoblastic leukaemia of adults. M.R.C. Adult Leukaemia Working Party. Br J Haematol 95(4):673–677 63. Raynaud S, Mauvieux L, Cayuela JM, et al. (1996) TEL/AML1 fusion gene is a rare event in adult acute lymphoblastic leukemia. 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E.H. Estey · S.H. Faderl · H. M.
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E. H. Estey Department of Leukemia
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VI Table of Contents 14 Philadelphi
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VIII Contributors S. H. Faderl Depa
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X Contributors D. Wartenberg Depart
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Therapy of AML Elihu Estey Contents
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a 1.2 · Standard Therapy 3 Table 1
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a 1.2 · Standard Therapy 5 Table 1
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a 1.2 · Standard Therapy 7 tween G
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a 1.2 · Standard Therapy 9 Fig. 1.
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a 1.2 · Standard Therapy 11 of tre
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a 1.2 · Standard Therapy 13 Table
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a 1.2 · Standard Therapy 15 permit
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a References 17 19. Care RS, Valk P
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a References 19 6-thioguanine in th
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Acute Myeloid Leukemia: Epidemiolog
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a 3.1 · Epidemiology 49 3.1.4 Gend
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a 3.2 · Etiology 51 part of the in
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Page 39 and 40: a References 55 38. Crane MM, Stom
Page 41 and 42: Relapsed and Refractory Acute Myelo
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Page 47 and 48: a 4.4 · Hematopoietic Stem Cell Tr
Page 49 and 50: a 4.6 · Gemtuzumab Ozogamicin 65 T
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Page 55 and 56: a References 71 The ability of immu
Page 57 and 58: a References 73 39. Vogler WR, McCa
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Page 61 and 62: Part II - Acute Lymphoblastic Leuke
Page 63 and 64: 78 Chapter 5 · Acute Lymphoblastic
Page 79 and 80: Molecular Biology and Genetics Meir
Page 81 and 82: a 6.3 · Structural Aberrations 97
Page 83 and 84: a 6.3 · Structural Aberrations 99
Page 85 and 86: a 6.5 · Molecular Aberrations 101
Page 87: a References 103 clear that homozyg
Page 91 and 92: a References 107 122. Lennard L, Li
Page 93 and 94: Diagnosis of Acute Lymphoblastic Le
Page 95 and 96: a 8.3 · Cytochemistry and Immunoph
Page 97 and 98: a 8.5 · Cytogenetic and Molecular
Page 99 and 100: a 8.5 · Cytogenetic and Molecular
Page 101 and 102: a References 127 including the reti
Page 103 and 104: a References 129 47. Kita K, Shirak
Page 105 and 106: Acute Lymphoblastic Leukemia: Clini
Page 107 and 108: a 7.3 · Diagnosis 111 or neoplasti
Page 109 and 110: a 7.3 · Diagnosis 113 Fig. 7.2. Hi
Page 111 and 112: a 7.3 · Diagnosis 115 The vast maj
Page 113 and 114: a References 117 dren: Biologic bas
Page 115 and 116: General Approach to the Therapy of
Page 117 and 118: a 9.3 · New Agents 133 dose methot
Page 119 and 120: a References 135 4. Gökbuget N, Ho
Page 121 and 122: 138 Chapter 10 · Recent Clinical T
Page 129 and 130: 146 Chapter 11 · Conventional Ther
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156 Chapter 11 · Conventional Ther
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158 Chapter 11 · Conventional Ther
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ALL Therapy: Review of the MD Ander
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a 12.2 · The Hyper-CVAD Regimen in
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a 12.3 · Subset-Specific Approache
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Treatment of Adult ALL According to
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a 13.2 · Therapy for Younger (15-6
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a 13.3 · Therapy of Ph/BCR-ABL-Pos
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a 13.5 · Prognostic Factors 173 13
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a References 175 Only patients with
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Philadelphia Chromosome-Positive Ac
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a 14.2 · Molecular Biology of the
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a 14.3 · Treatment of Ph+ ALL 181
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a 14.4 · Hematopoietic Stem Cell T
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a References 185 2. Kurzrock R, Sht
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a References 187 56. Mori T, Manabe
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a References 189 acute lymphoblasti
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192 Chapter 15 · Burkitt’s Acute
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204 Chapter 16 · Treatment of Lymp
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216 Chapter 17 · The Role of Allog
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230 Chapter 18 · The Role of Autol
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238 Chapter 19 · Novel Therapies i
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248 Chapter 20 · Minimal Residual
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264 Chapter 21 · Central Nervous S
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276 Chapter 22 · Relapsed Acute Ly
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278 Chapter 22 · Relapsed Acute Ly
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Emergencies in Acute Lymphoblastic
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a 23.5 · Hyperleukocytosis 283 LA
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a 23.9 · Neurological Complication
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a References 287 29. Hingorani AD,
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Subject Index A aberrant methylatio
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a Subject Index 291 CREB, see enhan
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a Subject Index 293 MUD, see matche
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