Letno poročilo 2005

- Asimetri~no hidrogeniranje s prenosom vodika
endocikli~nih C=N vezi s kiralnimi aminsulfamoilamidnimi
Ru-katalizatorji razvitimi
v na{em laboratoriju, pri ~emer so nastali kiralni
cikli~ni amini v visokem enantiomernem
prese`ku
- Sinteza novih poliaminskih derivatov za
prepre~evanje sepse
- Sinteza novih fluoriranih antibiotikov
SODELOVANJE Z INDUSTRIJSKIMI
IN DRUGIMI PARTNERJI
- Lek farmacevtska dru`ba d.d., Ljubljana; Sinteza
potencialnih farmacevtskih u~inkovin
- PhosPhoenix SARL, Pariz, Francija; Razvoj
novih industrijskih procesov na osnovi homogene
katalize
MEDNARODNO SODELOVANJE
- Slovensko - francoski bilateralni projekt PRO-
TEUS, 2004 - 2005 (Univerza Louis Pasteur,
SLIKA 1:
Sistem za hidrogeniranje pri 1 atm H v odsotnosti
2
zraka
Laboratorij za organsko sintezo in kemijo zdravil
Laboratory for Organic and Medicinal Chemistry
- Asymmetric transfer hydrogenation of endocyclic
C=N bonds to obtain chiral cyclic
amines in high enantiomeric excesses with
our laboratory developed chiral amine-sulfamoylamide
Ru-catalysts
- Synthesis of novel polyamine derivatives for
preventing sepsis
- Synthesis of new fluorinated antibiotics
COLLABORATION WITH INDUSTRIAL AND
OTHER PARTNERS
- Lek Pharmaceuticals, d.d., Ljubljana, Slovenia:
Synthesis of potential pharmaceutical
compounds
- PhosPhoenix SARL, Paris, France: Development
of industrial processes based on homogeneous
catalysis
INTERNATIONAL COLLABORATION
- Slovenian - French bilateral project PROTEUS,
2004 - 2005 (University of Louis Pasteur,
FIGURE 1:
System for hydrogenation at 1 atm of H with exclu-
2
sion of air
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