Letno poročilo 2005

Laboratorij za organsko sintezo in kemijo zdravil
Laboratory for Organic and Medicinal Chemistry
Strasbourg, Francija): Novi katalizatorji za
asimetri~no hidrogeniranje s prenosom vodika
vezani na nosilec
POMEMBNI IN[TRUMENTI IN OPREMA
- HPLC in GC sistemi opremljeni s kiralnimi
kolonami
- Polarimeter
- Ultra kriomat (-100 do +100 °C)
- Sistem za hidrogeniranje (do 100 atm H ) 2
SHEMA 1
Primer asimetri~nega hidrogeniranja s prenosom
vodika 1-metil-6,7-dimetoksi-3,4-dihidroizokinolina
z ¢Ru(Me 2 NSO 2 DPEN)(p-cimen)¥ katalizatorjem
110
Strasbourg, France): New supported catalysts
for asymmetric transfer hydrogenation
MAJOR EQUIPMENT
- HPLC and GC systems equipped with chiral
columns
- Polarimeter
- Ultra kryomat (-100 to +100 °C)
- System for hydrogenation (up to 100 atm H ) 2
SCHEME 1
An example of asymmetric transfer hydrogenation
of 1-methyl-6,7-dimethoxy-3,4-dihydroisoquinoline
with ¢Ru(Me 2 NSO 2 DPEN)(p-cymene)¥ catalyst