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Chapter 1 - Caltrans - State of California

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<strong>Chapter</strong> 3 Comments and Coordination<br />

Exposure to toxics has been a focus <strong>of</strong> a number <strong>of</strong> EPA efforts. Most notably, the<br />

agency conducted the National Air Toxics Assessment (NATA) in 1996 to evaluate<br />

modeled estimates <strong>of</strong> human exposure applicable to the county level. While not intended<br />

for use as a measure <strong>of</strong> or benchmark for local exposure, the modeled estimates in the<br />

NATA database best illustrate the levels <strong>of</strong> various toxics when aggregated to a national<br />

or state level.<br />

The EPA is in the process <strong>of</strong> assessing the risks <strong>of</strong> various kinds <strong>of</strong> exposures to these<br />

pollutants. The EPA Integrated Risk Information System (IRIS) is a database <strong>of</strong> human<br />

health effects that may result from exposure to various substances found in the<br />

environment. The IRIS database is located at http://www.epa.gov/iris. The following<br />

toxicity information for the six prioritized MSATs was taken from the IRIS database:<br />

• Benzene is characterized as causing decreased lymphocyte count and has non-cancer<br />

health endpoints <strong>of</strong> potential concern.<br />

• Acrolein the primary health concern is not cancer, but rather a respiratory endpoint.<br />

• Formaldehyde has respiratory endpoints and has non-cancer health endpoints <strong>of</strong><br />

potential concern.<br />

• 1,3-Butadiene is characterized as causing ovarian atrophy and has non-cancer health<br />

endpoints <strong>of</strong> potential concern.<br />

• Acetaldehyde is characterized as causing degeneration <strong>of</strong> the olfactory epithelium<br />

and has non-cancer health endpoints <strong>of</strong> potential concern.<br />

• Diesel exhaust (DE) is likely to be carcinogenic to humans by inhalation from<br />

environmental exposures. Diesel exhaust as reviewed in this document is the<br />

combination <strong>of</strong> diesel particulate matter and diesel exhaust organic gases. The<br />

particulate matter fraction <strong>of</strong> diesel exhaust (Diesel PM) has been identified by the<br />

CARB as a toxic air contaminant due to long-term cancer risk.<br />

• Diesel exhaust is also connected with chronic respiratory effects, possibly the<br />

primary noncancer hazard from MSATs. Prolonged exposures may impair pulmonary<br />

function and could produce symptoms, such as cough, phlegm, and chronic<br />

bronchitis. Exposure relationships have not been developed from these studies.<br />

There have been other studies that address MSAT health impacts in proximity to<br />

roadways. The Health Effects Institute, a non-pr<strong>of</strong>it organization funded by EPA,<br />

FHWA, and industry, has undertaken a major series <strong>of</strong> studies to research near-roadway<br />

IS/EA VEN-SB US101 HOV Project 151

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