20.08.2013 Views

PhD thesis - University of Hertfordshire Research Archive

PhD thesis - University of Hertfordshire Research Archive

PhD thesis - University of Hertfordshire Research Archive

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

to indigenously acquired infection with those which included all cases. For<br />

each continuous variable (the number <strong>of</strong> risk factors identified; number <strong>of</strong><br />

cases included; number <strong>of</strong> controls included; number <strong>of</strong> variables<br />

investigated; the exposure period in days, the overall study sample size; the<br />

ratio <strong>of</strong> cases to controls) Stata‟s „ladder‟ command was used to determine<br />

the transformation which best converted that variable into a normally or near-<br />

normally distributed variable, then that transformation was performed on that<br />

variable.<br />

The effect <strong>of</strong> each <strong>of</strong> these variables on the outcome <strong>of</strong> interest (the<br />

transformed number <strong>of</strong> reported risk factors) was investigated initially using<br />

single variable Poisson regression. Variables significantly associated with the<br />

outcome <strong>of</strong> interest at or above the 90% level were then included in a<br />

multiple variable Poisson regression model which was simplified using the<br />

likelihood ratio test.<br />

161

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!