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final program.qxd - Parallels Plesk Panel

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PP 3.2<br />

Is Age a Complicating Factor for Patients with Persistent Low Level Viremia?<br />

Boly L,Cafaro V, Dyner T<br />

Shared Perspectives on Therapies, San Francisco, United States<br />

Objectives<br />

Antiretroviral (ARV) regimens have become simplified with once daily dosing and<br />

decreased pill count. Side effects do persist for some patients and adherence remains a<br />

complicated issue. Continuing viral replication is thought to impact future treatment<br />

options and immunologic competence. Many patients decide to remain on their stable<br />

ARV treatment regimen despite the presence of low level viremia. While it has been<br />

documented that length of time on ARVs as well as nadir CD4 counts may influence side<br />

effects, chronological age may also contribute. We evaluated a group of patients with low<br />

level viremia and good adherence to their ARV regimens for any impact of chronological<br />

age on the experience of adverse side effects.<br />

Methods<br />

A retrospective chart review was conducted of 24 patients on stable ARV treatment<br />

regimens who had persistent low level viremia (HIV bDNA levels

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