final program.qxd - Parallels Plesk Panel

PP 3.10
Mycological Findings From HIV-Positive Children and Adults in Nairobi, kenia
Mashedi O.M M 1 ,. Bii.C.C 2 , Amukoye E. 1 , Kumon.K. 3 , Mwangi I 1 , Mohamed A 2 ., Ouko.T.T 2 ,
Njoroge N.W. 1 , Wambua M 2 , Mwangi.P 3 . Obanda A.P. 2 , Muita L 1 , Ukon.T 3 , Kanamoto 3 .
1
Center for Respiratory Research Disease, KEMRI. 2 Center for Microbiology Research,
KEMRI. 3 Japan International Cooperation Agency (JICA).
Corresponding author: Ms Olga Mashedi Email:omukasia@yahoo.com
Introduction
HIV/AIDS infection leads to an increase in opportunistic infections. Among these infections
some are mycological. Candida albicans, is usually a normal flora, but it is emerging as
an opportunistic pathogen. The objective of this study was to determine the fungal
diversity in various specimens from children and adults infected with HIV in Nairobi,
Kenya.
Materials and Methods
Mycological investigations were carried out on various specimens from HIV/AIDS infected
children in an orphanage and adults in Mbagathi District Hospital, Nairobi. 120 specimens
(swabs, blood, urine, sputum, saliva, high vaginal swabs, bronchiole alveolar lavage and
skin scrapings were processed using standard procedures.
Results
Isolated included fungi, C.albicans (70%), C.glabrata (50%), C.parapsilosis and C.tropicalis
(40%), Moulds such as Aspergillus versicolor, Trichophyton schoenleinii, Fusarium
semitectum, Bipolari hawaiiensis (from blood) and Malassezia furfur were also isolated
Conclusion
From the various specimens, incidence of C.albicans in children was relatively higher than
that in adults.C.glabrata, C.parapsilosis, C.Tropicalis isolated in this study have
previously been documented to have high virulence leading to severity associated with
these infections. Moulds such as, Aspergillus versicolor, Trichophytonschoenleinii
Fusarium semitctum Bipolari hawaiiensis(from blood) and Malassezia fur fur most of
which were isolated in children. The reason for this is yet to be delineated. The results
indicate a need for further studies to better understand of these emerging opportunistic
infections for easier management.
POSTERS
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