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OP 8.3<br />

Epidemiology and Control of Avian Influenza<br />

Arjan Stegeman<br />

Faculty of Veterinary Medicine - Department of Farm Animal Health<br />

Introduction<br />

Infections with Avian Influenza (AI) viruses are common in various mammal and bird<br />

species. AI is a notifiable animal disease (OIE), and outbreaks of AI were reported for<br />

decades in several countries, such as Mexico, Italy, The Netherlands, and Canada. Until<br />

a few years ago, AI, or fowl plague, was mainly considered being a veterinary problem,<br />

causing high mortality in poultry and severe economic damage for the poultry industry.<br />

Since the outbreaks of high pathogenicity (HPAI) H5N1 in Asia in 1997, however, AI also<br />

attracted the attention of public health organizations, as this strain caused the death of<br />

over 100 persons, and multiple numbers distracted the infection. Scientists are warning for<br />

a new influenza pandemic, and nowadays, the disease seems to be more a human<br />

health issue than a veterinary one.<br />

ABSTRACTS<br />

It should not be forgotten, however, that, at least until this moment, the disease mainly<br />

affected poultry and other birds. Especially the poultry industry in Asian countries, like<br />

Thailand, Vietnam, Cambodia, Indonesia and others, is struck by AI epidemics. Everyone<br />

saw pictures of desperate farmers and their families, farms being depopulated, people<br />

carrying bags full of chickens and throwing them into pits. The outbreaks seemed to be<br />

limited to this part of the world, but last year, the virus also spread to countries in the<br />

western hemisphere, such as Russia, Turkey, Romania, Slovenia, Germany, France and<br />

many other. These outbreaks were controlled rather quickly and relatively few farms<br />

became infected.<br />

In addition to this, it should be realized that other HPAI strains than H5N1 may emerge,<br />

and may cause epidemics in poultry or a new human pandemic. This year, Europe only<br />

had localized outbreaks of H5N1, but three years ago, The Netherlands was confronted<br />

with a huge epidemic of H7N7, during which 30 million poultry were killed and one<br />

veterinarian died. So we know how devastating an AI infection for the poultry industry can<br />

be, and how large the impact is on the society.<br />

Because of the devastating effect for poultry and the possible public health risk, outbreaks<br />

of HPAI should be controlled as quickly as possible. From a veterinary perspective, but<br />

also from a human health point of view, the disease should be controlled at the source,<br />

i.e. the poultry farm. Especially, prompt reduction of the virus output is very important, with<br />

respect to reduction of the exposure for poultry and humans.<br />

Control of AI<br />

To stop epidemics of HPAI, knowledge of the effectiveness of the control measures<br />

implemented during an epidemic is of vital importance. Four issues that are logically<br />

related to the epidemiology of Avian Influenza will be addressed, mainly with respect to<br />

the Dutch epidemic.<br />

“ Focusing FIRST on PEOPLE “ 65 w w w . i s h e i d . c o m

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