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final program.qxd - Parallels Plesk Panel

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PP 3.7<br />

Functional limitation of Mycobacterium ulcerans cutaneous infections (Buruli<br />

ulcer): usefulness of a functional limitation score<br />

Rapp C,Ficko C, Imbert P, Barruet R, Debord T<br />

Department of infectious and tropical diseases Military Hospital Bégin 69 avenue de Paris,<br />

94163 Saint-Mandé, France<br />

Buruli ulcer disease, caused by Mycobacterium ulcerans, is emerging in West Africa. Their<br />

low case fatality rate is contrasting with the significant morbidity and the growing<br />

ocio-economic impact of the osteoarticular sequelae.<br />

Objective<br />

To describe and quantify the functional sequelae of M ulcerans cutaneous infections in<br />

Ivory Coast.<br />

Patients and methods: All children over 2 years old and adults presenting with a Buruli<br />

ulcer (BU) and treated since 2003 for more than 3 months were included in a 3 month<br />

period. The functional damage was evaluated with a simplified quantitative score (a<br />

questionnaire of 15 items adapted to daily life activities) inspired from the Buruli ulcer<br />

functional score validated in Ghana by Stienstra an al (Am J Trop Med Hyg 2004).<br />

Results<br />

186 patients (96 males, 90 females) with a mean age of 16.5 years (3-72) were included.<br />

The distribution of the 230 observed lesions was: upper limbs (42%), lower limbs (52%),<br />

trunk and face (6%). The sequelae rate was 36.6% (n=68) with a mean functional<br />

handicap score of 18.6% (0-80). The amputation rate was 4%. The worst affected were<br />

children (23.4 vs 13.3%).The functional incapability of the patients resulted in 30% of the<br />

children being taken out of the school system and 40% of the adults losing their job.<br />

Comments<br />

Our results confirm the significance of sequelae and their impact on precarious and rural<br />

populations. The quantitative functional score is a simple and reliable tool. Its distribution<br />

in health care centers should allow the measuring of individual benefit of physiotherapy.<br />

On the community level, it can be used to evaluate necessary resources and to compare<br />

the effectiveness of the therapeutic interventions. The search for sequelae risk factors and<br />

appropriate management are urgent.<br />

POSTERS<br />

“ Focusing FIRST on PEOPLE “ 147 w w w . i s h e i d . c o m

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