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EMQs in Clinical Medicine.pdf - Peshawar Medical College

EMQs in Clinical Medicine.pdf - Peshawar Medical College

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Neurology – revision boxes 105<br />

REVISION BOXES<br />

Neurology<br />

Box 1 summarizes some features of different causes of headache.<br />

Box 1 Headache: classic presentation <strong>in</strong> an EMQ [29, 30]<br />

Symptoms<br />

Headache type<br />

• Stress, tight band around head Tension headache<br />

• Sudden onset, ‘kicked <strong>in</strong> back Subarachnoid haemorrhage<br />

of head’; associated with vomit<strong>in</strong>g<br />

• Unilateral ‘throbb<strong>in</strong>g’, aura, Migra<strong>in</strong>e<br />

vomit<strong>in</strong>g, photophobia<br />

• Tender pulseless temporal<br />

Giant-cell arteritis<br />

arteries; jaw claudication<br />

• Pa<strong>in</strong> worse on cough<strong>in</strong>g/sneez<strong>in</strong>g; Mass lesion<br />

confusion, seizures, localiz<strong>in</strong>g focal<br />

neurology; signs of <strong>in</strong>tracranial<br />

pressure, e.g. papilloedema<br />

• Usually obese young woman; ↑ CSF Benign <strong>in</strong>tracranial hypertension<br />

(cerebrosp<strong>in</strong>al fluid) pressure but<br />

no mass lesion<br />

• Fever, neck stiffness,<br />

Men<strong>in</strong>gitis<br />

photophobia, rash<br />

• Head <strong>in</strong>jury, chronic course<br />

Subdural haemorrhage<br />

fluctuat<strong>in</strong>g consciousness<br />

Discrim<strong>in</strong>at<strong>in</strong>g an upper motor neuron lesion (UMN) from a lower motor<br />

neuron (LMN) lesion helps to exclude options <strong>in</strong> an EMQ (Box 2).<br />

Box 2 Dist<strong>in</strong>guish<strong>in</strong>g UMN and LMN lesions<br />

UMN lesion<br />

LMN lesion<br />

• Involves corticosp<strong>in</strong>al tract<br />

• Lesion at level of anterior horn<br />

• Weakness <strong>in</strong> upper limb extensors, cell or distal to it<br />

lower limb flexors (pyramidal • Fasciculation and wast<strong>in</strong>g<br />

distribution)<br />

• Loss reflexes<br />

• Increased tone<br />

• Hypotonia<br />

• Hyperreflexia, clonus<br />

• Pronator drift<br />

• Loss of abdom<strong>in</strong>al reflexes<br />

• Extensor plantar response

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