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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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Respiratory medic<strong>in</strong>e – revision boxes 49<br />

Box 3 Chest radiograph [14, 15]<br />

Radiological change<br />

• Kerley B l<strong>in</strong>es<br />

Bat-w<strong>in</strong>g shadow<strong>in</strong>g<br />

• Tram-l<strong>in</strong>e shadow<strong>in</strong>g<br />

• Miliary shadow<strong>in</strong>g<br />

• Wedge-shaped <strong>in</strong>farct<br />

• ‘Ground-glass’ appearance<br />

‘Honeycomb’ appearance<br />

• Pleural mass with lobulated marg<strong>in</strong><br />

Pathology<br />

Heart failure<br />

Bronchiectasis<br />

Miliary TB<br />

Pulmonary embolus<br />

Fibrosis<br />

Fibrosis (late)<br />

Mesothelioma<br />

Box 4 summarizes some details to look out for <strong>in</strong> an EMQ which suggest a<br />

particular respiratory condition.<br />

Box 4 Respiratory conditions<br />

Factor <strong>in</strong>dicat<strong>in</strong>g diagnosis<br />

Condition<br />

• Early-onset emphysema plus liver disease 1 -Antitryps<strong>in</strong> deficiency [57]<br />

Fever, cough, shortness of breath hours Extr<strong>in</strong>sic allergic alveolitis [11]<br />

after exposure to antigen (usually farmer<br />

after hay exposure)<br />

Positive serum precipit<strong>in</strong>s<br />

• Asymptomatic with bilateral hilar Sarcoidosis [5, 15]<br />

lymphadenopathy (BHL)/progressive<br />

shortness of breath/dry cough<br />

Non-pulmonary manifestations,<br />

e.g. erythema nodosum<br />

↑ serum ACE (angiotens<strong>in</strong>-convert<strong>in</strong>g<br />

enzyme) or hypercalcaemia may be<br />

mentioned<br />

• History of recurrent chest <strong>in</strong>fections, Cystic fibrosis [11, 15, 74]<br />

failure to thrive<br />

May mention steatorrhoea (pancreatic<br />

<strong>in</strong>sufficiency)<br />

Positive sweat test (sodium,<br />

chloride 60 mmol/l)<br />

• Progressive dyspnoea and cyanosis Fibros<strong>in</strong>g alveolitis [15]<br />

Gross clubb<strong>in</strong>g, f<strong>in</strong>e end-<strong>in</strong>spiratory<br />

crackles<br />

Chest radiograph: ground-glass →<br />

honeycomb lung<br />

cont<strong>in</strong>ued overleaf

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