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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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Neurology – revision boxes 107<br />

Box 4 Features of eponymous syndromes<br />

Feature<br />

Syndrome<br />

• Saddle anaesthesia<br />

Cauda equ<strong>in</strong>a syndrome<br />

Bowel/bladder disturbance<br />

Bilateral pa<strong>in</strong> legs<br />

• Ipsilateral pyramidal signs plus<br />

Brown–Séquard syndrome<br />

contralateral loss of pa<strong>in</strong> and<br />

temperature<br />

• Ascend<strong>in</strong>g symmetrical flaccid Guilla<strong>in</strong>–Barré syndrome [31, 96]<br />

muscle weakness<br />

Preced<strong>in</strong>g recent respiratory/<br />

gastro<strong>in</strong>test<strong>in</strong>al <strong>in</strong>fection<br />

• Comb<strong>in</strong>ation of park<strong>in</strong>sonism plus Shy–Drager syndrome<br />

primary autonomic failure, e.g.<br />

postural hypotension<br />

• Triad of: nystagmus,<br />

Wernicke’s encephalopathy<br />

ophthalmoplegia, ataxia [79, 99]<br />

Caused by thiam<strong>in</strong>e (vitam<strong>in</strong> B 1 )<br />

deficiency<br />

Reversible but if untreated develops<br />

to Korsakoff’s syndrome<br />

• Signs of gross defect <strong>in</strong> memory of Korsakoff’s syndrome<br />

recent events<br />

Confabulation may be present<br />

Condition is irreversible<br />

Description of the patient’s gait is often a good clue to a particular option <strong>in</strong> an<br />

EMQ (Box 5).<br />

Box 5 Gait and different conditions [36]<br />

Gait<br />

Condition<br />

Shuffl<strong>in</strong>g, fest<strong>in</strong>ant gait Park<strong>in</strong>son’s disease<br />

High-stepp<strong>in</strong>g/stamp<strong>in</strong>g gait Sensory ataxia, e.g. peripheral neuropathy<br />

Scissor gait<br />

Spastic paraplegia<br />

Wide-based gait<br />

Cerebellar lesion<br />

Shuffl<strong>in</strong>g small steps Cerebrovascular disease (marche à la petit pas)<br />

You will frequently come across an EMQ that tests knowledge of nerve root<br />

<strong>in</strong>nervation and understand<strong>in</strong>g of the level of a lesion when particular<br />

symptoms/signs are described (Box 6).

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