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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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Treatment of peripheral vascular disease – answers 181<br />

H<br />

A 58-year-old person with diabetes presents with a pa<strong>in</strong>less punchedout<br />

ulcer on the sole of the right foot. The surround<strong>in</strong>g area has<br />

reduced pa<strong>in</strong> sensation.<br />

Neuropathic ulcers occur as a result of impaired sensation caused by<br />

neurological deficit of whatever cause. Diabetes mellitus is the most<br />

common cause of neuropathic ulcers. They are characteristically pa<strong>in</strong>less.<br />

67 Treatment of peripheral vascular disease<br />

Answers: K C I B G<br />

K<br />

C<br />

I<br />

A 75-year-old smoker presents with severe rest pa<strong>in</strong> <strong>in</strong> her right leg.<br />

On exam<strong>in</strong>ation there is advanced gangrene of the right foot with<br />

absent pulses distal to the popliteal pulse.<br />

It is especially important to counsel the patient adequately for such a<br />

measure. A below-knee amputation is <strong>in</strong>dicated here because there<br />

is considerable risk of systemic <strong>in</strong>fection and advancement of the<br />

gangrene. The signs of critical limb ischaemia are sometimes summarized<br />

as the six ‘P’s: pa<strong>in</strong>, paraesthesia, pallor, pulselessness, paralysis and<br />

perish<strong>in</strong>g with cold.<br />

A 55-year-old overweight smoker presents with pa<strong>in</strong> <strong>in</strong> his legs after<br />

walk<strong>in</strong>g half a mile, which is relieved immediately by rest. Ankle<br />

brachial pressure <strong>in</strong>dex is 0.8.<br />

This patient has a relatively large claudication distance (distance travelled<br />

before he gets pa<strong>in</strong>) which implies that he does not require <strong>in</strong>vasive<br />

treatment.<br />

Ankle brachial pressure <strong>in</strong>dex of above 0.9 is normal. Patients with claudication<br />

but no rest pa<strong>in</strong> usually have a value that is between 0.6 and<br />

0.9. A value below 0.6 is associated with rest pa<strong>in</strong> and critical ischaemia.<br />

Cessation of smok<strong>in</strong>g, more exercise and weight reduction are useful<br />

<strong>in</strong>itial measures for the patient <strong>in</strong> this scenario.<br />

<strong>Medical</strong> <strong>in</strong>tervention <strong>in</strong>cludes the treatment of diabetes, hypertension<br />

and hyperlipidaemia.<br />

Daily low-dose aspir<strong>in</strong> is <strong>in</strong>dicated.<br />

A 62-year-old man presents with severe bilateral pa<strong>in</strong> <strong>in</strong> the legs. He<br />

is known to suffer from impotence and buttock claudication. Femoral<br />

pulses are weak. Arteriography shows stenosis <strong>in</strong> both common iliac<br />

arteries with good distal run-off.<br />

The distal aorta bifurcates <strong>in</strong>to the two common iliac arteries (the median<br />

sacral branch is also given off). The common iliac artery divides to form the<br />

external and <strong>in</strong>ternal iliac arteries. The external iliac artery passes under the<br />

<strong>in</strong>gu<strong>in</strong>al ligament to become the femoral artery. An aorto-bifemoral bypass<br />

will thus provide better circulation distal to the occlusions/narrow<strong>in</strong>g.

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