EMQs in Clinical Medicine.pdf - Peshawar Medical College
EMQs in Clinical Medicine.pdf - Peshawar Medical College
EMQs in Clinical Medicine.pdf - Peshawar Medical College
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124 Orthopaedics and rheumatology<br />
ANSWERS<br />
42 Arthritis<br />
Answers: C N E H A<br />
C<br />
N<br />
E<br />
H<br />
A 54-year-old woman presents to her GP with swollen pa<strong>in</strong>ful hands<br />
and feet, which are stiffer <strong>in</strong> the morn<strong>in</strong>gs. On exam<strong>in</strong>ation there are<br />
signs of ulnar deviation and subluxation at the MCP jo<strong>in</strong>ts.<br />
Ulnar deviation and subluxation of MCP jo<strong>in</strong>ts are signs of advanced<br />
disease. Swell<strong>in</strong>g of the f<strong>in</strong>gers (sausage-like) and MCP jo<strong>in</strong>t swell<strong>in</strong>g are<br />
earlier signs.<br />
A 65-year-old woman compla<strong>in</strong>s of pa<strong>in</strong> <strong>in</strong> her f<strong>in</strong>gers on movement,<br />
which is worst at the end of the day. On exam<strong>in</strong>ation there is jo<strong>in</strong>t<br />
tenderness and bony lumps at the DIP jo<strong>in</strong>ts. A radiograph shows loss<br />
of jo<strong>in</strong>t space.<br />
The radiological changes of osteoarthritis <strong>in</strong>clude loss of jo<strong>in</strong>t space,<br />
subchondral sclerosis, osteophytes and subchondral cyst formation.<br />
Osteophytes at the proximal <strong>in</strong>terphalangeal and DIP jo<strong>in</strong>ts are called<br />
Bouchard’s and Heberden’s nodes respectively. Previous jo<strong>in</strong>t damage is a<br />
risk factor for the development of osteoarthritic disease. Simple analgesics<br />
such as paracetamol should be prescribed for pa<strong>in</strong> relief rather<br />
than long courses of non-steroidal anti-<strong>in</strong>flammatory drugs (NSAIDs)<br />
(risk of gastro<strong>in</strong>test<strong>in</strong>al bleed<strong>in</strong>g with prolonged use).<br />
A 30-year-old woman compla<strong>in</strong>s of jo<strong>in</strong>t pa<strong>in</strong> <strong>in</strong> her hands and feet.<br />
Her chest radiograph shows reduced lung volumes.<br />
Systemic lupus erythematosus (SLE) is an <strong>in</strong>flammatory multisystemic<br />
disorder that is n<strong>in</strong>e times more common <strong>in</strong> women than <strong>in</strong> men. The<br />
jo<strong>in</strong>ts are most often affected <strong>in</strong> a symmetrical fashion with no bony<br />
erosion (unlike rheumatoid arthritis). Rarely, there may be markedly<br />
deformed jo<strong>in</strong>ts caused by jo<strong>in</strong>t laxity that resemble rheumatoid arthritis<br />
(Jaccoud’s arthropathy).<br />
Lung <strong>in</strong>volvement occurs <strong>in</strong> up to half of patients with SLE.<br />
Manifestations <strong>in</strong>clude pleuritic chest pa<strong>in</strong>, pleural effusions (these are<br />
common and often bilateral), acute/chronic pneumonitis and the rare<br />
‘shr<strong>in</strong>k<strong>in</strong>g lung syndrome’.<br />
A 22-year-old man presents with an acute arthritis of the left knee,<br />
dysuria and bilateral conjunctivitis. He has recently suffered from<br />
gastroenteritis.<br />
Reiter’s disease <strong>in</strong>volves a triad of urethritis, conjunctivitis and seronegative<br />
arthritis. Jo<strong>in</strong>t symptoms may be the present<strong>in</strong>g compla<strong>in</strong>t. It is often