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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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124 Orthopaedics and rheumatology<br />

ANSWERS<br />

42 Arthritis<br />

Answers: C N E H A<br />

C<br />

N<br />

E<br />

H<br />

A 54-year-old woman presents to her GP with swollen pa<strong>in</strong>ful hands<br />

and feet, which are stiffer <strong>in</strong> the morn<strong>in</strong>gs. On exam<strong>in</strong>ation there are<br />

signs of ulnar deviation and subluxation at the MCP jo<strong>in</strong>ts.<br />

Ulnar deviation and subluxation of MCP jo<strong>in</strong>ts are signs of advanced<br />

disease. Swell<strong>in</strong>g of the f<strong>in</strong>gers (sausage-like) and MCP jo<strong>in</strong>t swell<strong>in</strong>g are<br />

earlier signs.<br />

A 65-year-old woman compla<strong>in</strong>s of pa<strong>in</strong> <strong>in</strong> her f<strong>in</strong>gers on movement,<br />

which is worst at the end of the day. On exam<strong>in</strong>ation there is jo<strong>in</strong>t<br />

tenderness and bony lumps at the DIP jo<strong>in</strong>ts. A radiograph shows loss<br />

of jo<strong>in</strong>t space.<br />

The radiological changes of osteoarthritis <strong>in</strong>clude loss of jo<strong>in</strong>t space,<br />

subchondral sclerosis, osteophytes and subchondral cyst formation.<br />

Osteophytes at the proximal <strong>in</strong>terphalangeal and DIP jo<strong>in</strong>ts are called<br />

Bouchard’s and Heberden’s nodes respectively. Previous jo<strong>in</strong>t damage is a<br />

risk factor for the development of osteoarthritic disease. Simple analgesics<br />

such as paracetamol should be prescribed for pa<strong>in</strong> relief rather<br />

than long courses of non-steroidal anti-<strong>in</strong>flammatory drugs (NSAIDs)<br />

(risk of gastro<strong>in</strong>test<strong>in</strong>al bleed<strong>in</strong>g with prolonged use).<br />

A 30-year-old woman compla<strong>in</strong>s of jo<strong>in</strong>t pa<strong>in</strong> <strong>in</strong> her hands and feet.<br />

Her chest radiograph shows reduced lung volumes.<br />

Systemic lupus erythematosus (SLE) is an <strong>in</strong>flammatory multisystemic<br />

disorder that is n<strong>in</strong>e times more common <strong>in</strong> women than <strong>in</strong> men. The<br />

jo<strong>in</strong>ts are most often affected <strong>in</strong> a symmetrical fashion with no bony<br />

erosion (unlike rheumatoid arthritis). Rarely, there may be markedly<br />

deformed jo<strong>in</strong>ts caused by jo<strong>in</strong>t laxity that resemble rheumatoid arthritis<br />

(Jaccoud’s arthropathy).<br />

Lung <strong>in</strong>volvement occurs <strong>in</strong> up to half of patients with SLE.<br />

Manifestations <strong>in</strong>clude pleuritic chest pa<strong>in</strong>, pleural effusions (these are<br />

common and often bilateral), acute/chronic pneumonitis and the rare<br />

‘shr<strong>in</strong>k<strong>in</strong>g lung syndrome’.<br />

A 22-year-old man presents with an acute arthritis of the left knee,<br />

dysuria and bilateral conjunctivitis. He has recently suffered from<br />

gastroenteritis.<br />

Reiter’s disease <strong>in</strong>volves a triad of urethritis, conjunctivitis and seronegative<br />

arthritis. Jo<strong>in</strong>t symptoms may be the present<strong>in</strong>g compla<strong>in</strong>t. It is often

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