EMQs in Clinical Medicine.pdf - Peshawar Medical College

Antiepileptic drug therapy 85
39 Antiepileptic drug therapy
A
B
C
D
E
F
carbamazepine
tiagabine
paraldehyde
diazepam
sodium valproate
phenobarbitone
G
H
I
J
K
L
phenytoin
gabapentin
primidone
lamotrigine
ethosuximide
vigabatrin
For each clinical scenario, select the most probable antiepileptic medication
that is responsible for the adverse effects described. Each option may be used
only once.
1 A 45-year-old woman on antiepileptic therapy complains of acne and increased
facial hair growth. She is on no other medication.
2 A 25-year-old man presents with visual field defects 2 months after starting a
new anticonvulsant therapy.
3 A 21-year-old woman presenting with status epilepticus complains of rectal irritation
after being given an antiepileptic medication per rectum.
4 A 32-year-old woman on treatment for temporal lobe epilepsy complains of
tremor, drowsiness and thinning hair. She is found to have mildly raised liver
enzyme levels.
5 A 24-year-old man who has recently started adjunctive antiepileptic therapy
complains of a rash with blisters in the mouth and flu symptoms.
Answers: see page 101.