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EMQs in Clinical Medicine.pdf - Peshawar Medical College

EMQs in Clinical Medicine.pdf - Peshawar Medical College

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212 Metabolic and endocr<strong>in</strong>e disturbances<br />

The aim of Box 3 is to summarize some dist<strong>in</strong>ctive features of endocr<strong>in</strong>e<br />

disease that commonly appear <strong>in</strong> <strong>EMQs</strong>.<br />

Box 3 Endocr<strong>in</strong>e disturbance [78]<br />

Symptoms to look out for <strong>in</strong> questions:<br />

• Heat <strong>in</strong>tolerance, weight loss,<br />

diarrhoea, anxiety<br />

• Cold <strong>in</strong>tolerance, weight ga<strong>in</strong>, depression,<br />

constipation, dementia, depression<br />

• Change <strong>in</strong> facial appearance, visual<br />

problems<br />

• Weight ga<strong>in</strong>, hirsutism, menstrual<br />

problems, depression<br />

On exam<strong>in</strong>ation:<br />

• Buccal/palmar crease hyperpigmentation,<br />

postural hypotension<br />

• ‘Moon-shaped’ face, centripetal obesity,<br />

proximal myopathy, purple striae,<br />

hypertension, diabetes mellitus<br />

• Macroglossia, spade-like hands and feet<br />

• Bradycardia, dry th<strong>in</strong> hair, goitre, loss of<br />

outer third of eyebrow, slowly relax<strong>in</strong>g<br />

reflexes<br />

• Tachycardia, goitre, atrial fibrillation, lid lag<br />

Hyperthyroidism<br />

Hypothyroidism<br />

Acromegaly<br />

Cush<strong>in</strong>g’s syndrome<br />

Addison’s disease<br />

Cush<strong>in</strong>g’s disease<br />

Acromegaly<br />

Hypothyroidism<br />

Hyperthyroidism

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