EMQs in Clinical Medicine.pdf - Peshawar Medical College
EMQs in Clinical Medicine.pdf - Peshawar Medical College
EMQs in Clinical Medicine.pdf - Peshawar Medical College
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130 Orthopaedics and rheumatology<br />
Anti-ro antibodies are found <strong>in</strong> 75 per cent of patients with primary SS<br />
but only 10–15 per cent patients with secondary SS.<br />
A Schirmer’s test can be used to identify <strong>in</strong>sufficient production of tears.<br />
The test <strong>in</strong>volves plac<strong>in</strong>g a strip of filter paper on the <strong>in</strong>side of the lower<br />
lid. A wett<strong>in</strong>g (measured by the distance the water is absorbed up the<br />
paper) of less than 10 mm <strong>in</strong> 5 m<strong>in</strong> implies defective tear production.<br />
Salivary gland biopsy to identify the focal <strong>in</strong>filtrate of lymphocytes is<br />
the best s<strong>in</strong>gle test for diagnosis.<br />
Management <strong>in</strong>volves treat<strong>in</strong>g the symptoms with artificial tears and<br />
saliva.<br />
D<br />
A patient presents to rheumatology cl<strong>in</strong>ic with recurrent attacks of<br />
pa<strong>in</strong> and swell<strong>in</strong>g <strong>in</strong> the nose and external ear.<br />
Polychondritis is an <strong>in</strong>flammatory condition affect<strong>in</strong>g cartilage that<br />
ma<strong>in</strong>ly affects the nose and the ear. Other features <strong>in</strong>clude vasculitis and<br />
seronegative arthritis.<br />
47 Complications of fractures<br />
Answers: A H E G L<br />
A<br />
A 25-year-old man presents with a blue right arm with absent radial<br />
pulse and pa<strong>in</strong>ful passive f<strong>in</strong>ger extension after a supracondylar fracture<br />
of humerus.<br />
Fracture can lead to ischaemia <strong>in</strong> the distal limb by direct <strong>in</strong>jury to the<br />
blood vessel or by the effect of oedema <strong>in</strong>creas<strong>in</strong>g the pressure with<strong>in</strong><br />
the osteofascial compartment, which limits perfusion. In compartment<br />
syndrome, the <strong>in</strong>creased pressure can lead to profound ischaemia with<br />
necrosis of muscle and nerve tissue. This is a surgical emergency requir<strong>in</strong>g<br />
prompt decompression by open fasciotomy. Once muscle tissue has<br />
become <strong>in</strong>farcted, it is replaced by <strong>in</strong>elastic fibrous tissue giv<strong>in</strong>g rise to<br />
the complication of Volkmann’s ischaemic contracture.<br />
A 40-year-old woman presents 5 weeks after a radial fracture with a<br />
pa<strong>in</strong>ful swollen hand. The hand is cold and cyanosed with heightened<br />
temperature sensitivity.<br />
H This condition is now known as complex regional pa<strong>in</strong> syndrome type 1.<br />
The pa<strong>in</strong> and swell<strong>in</strong>g are close to, but not exactly at, the area of <strong>in</strong>jury.<br />
The sk<strong>in</strong> may be oedematous and there may be altered sweat production.<br />
Its aetiology is unknown.<br />
E<br />
A 70-year-old woman compla<strong>in</strong>s of right-sided pleuritic chest pa<strong>in</strong> 10<br />
days after a fractured neck of femur.<br />
Pleuritic chest pa<strong>in</strong> after orthopaedic/pelvic surgery should <strong>in</strong>voke strong<br />
suspicion of pulmonary embolus.