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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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130 Orthopaedics and rheumatology<br />

Anti-ro antibodies are found <strong>in</strong> 75 per cent of patients with primary SS<br />

but only 10–15 per cent patients with secondary SS.<br />

A Schirmer’s test can be used to identify <strong>in</strong>sufficient production of tears.<br />

The test <strong>in</strong>volves plac<strong>in</strong>g a strip of filter paper on the <strong>in</strong>side of the lower<br />

lid. A wett<strong>in</strong>g (measured by the distance the water is absorbed up the<br />

paper) of less than 10 mm <strong>in</strong> 5 m<strong>in</strong> implies defective tear production.<br />

Salivary gland biopsy to identify the focal <strong>in</strong>filtrate of lymphocytes is<br />

the best s<strong>in</strong>gle test for diagnosis.<br />

Management <strong>in</strong>volves treat<strong>in</strong>g the symptoms with artificial tears and<br />

saliva.<br />

D<br />

A patient presents to rheumatology cl<strong>in</strong>ic with recurrent attacks of<br />

pa<strong>in</strong> and swell<strong>in</strong>g <strong>in</strong> the nose and external ear.<br />

Polychondritis is an <strong>in</strong>flammatory condition affect<strong>in</strong>g cartilage that<br />

ma<strong>in</strong>ly affects the nose and the ear. Other features <strong>in</strong>clude vasculitis and<br />

seronegative arthritis.<br />

47 Complications of fractures<br />

Answers: A H E G L<br />

A<br />

A 25-year-old man presents with a blue right arm with absent radial<br />

pulse and pa<strong>in</strong>ful passive f<strong>in</strong>ger extension after a supracondylar fracture<br />

of humerus.<br />

Fracture can lead to ischaemia <strong>in</strong> the distal limb by direct <strong>in</strong>jury to the<br />

blood vessel or by the effect of oedema <strong>in</strong>creas<strong>in</strong>g the pressure with<strong>in</strong><br />

the osteofascial compartment, which limits perfusion. In compartment<br />

syndrome, the <strong>in</strong>creased pressure can lead to profound ischaemia with<br />

necrosis of muscle and nerve tissue. This is a surgical emergency requir<strong>in</strong>g<br />

prompt decompression by open fasciotomy. Once muscle tissue has<br />

become <strong>in</strong>farcted, it is replaced by <strong>in</strong>elastic fibrous tissue giv<strong>in</strong>g rise to<br />

the complication of Volkmann’s ischaemic contracture.<br />

A 40-year-old woman presents 5 weeks after a radial fracture with a<br />

pa<strong>in</strong>ful swollen hand. The hand is cold and cyanosed with heightened<br />

temperature sensitivity.<br />

H This condition is now known as complex regional pa<strong>in</strong> syndrome type 1.<br />

The pa<strong>in</strong> and swell<strong>in</strong>g are close to, but not exactly at, the area of <strong>in</strong>jury.<br />

The sk<strong>in</strong> may be oedematous and there may be altered sweat production.<br />

Its aetiology is unknown.<br />

E<br />

A 70-year-old woman compla<strong>in</strong>s of right-sided pleuritic chest pa<strong>in</strong> 10<br />

days after a fractured neck of femur.<br />

Pleuritic chest pa<strong>in</strong> after orthopaedic/pelvic surgery should <strong>in</strong>voke strong<br />

suspicion of pulmonary embolus.

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