EMQs in Clinical Medicine.pdf - Peshawar Medical College
EMQs in Clinical Medicine.pdf - Peshawar Medical College
EMQs in Clinical Medicine.pdf - Peshawar Medical College
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Haemoptysis – answers 39<br />
and Mycoplasma spp., if psittacosis is suspected, treatment should be<br />
commenced with a macrolide antibiotic.<br />
C<br />
H<br />
A<br />
A 40-year-old man with HIV presents with fever, dry cough, weight<br />
loss and exertional dyspnoea.<br />
This is a presentation of Pneumocystis car<strong>in</strong>ii <strong>in</strong>fection, which is a common<br />
complication of HIV <strong>in</strong>fection (AIDS-def<strong>in</strong><strong>in</strong>g illness). It may also<br />
occur as an opportunistic <strong>in</strong>fection <strong>in</strong> other immunocompromised<br />
patients such as those receiv<strong>in</strong>g immunosuppressive drugs and cancer<br />
chemotherapy.<br />
A 75-year-old man presents with headache, dry cough, anaemia and<br />
a sk<strong>in</strong> rash. Blood tests detect cold agglut<strong>in</strong><strong>in</strong>s.<br />
Mycoplasma <strong>in</strong>fection is the most common atypical cause of communityacquired<br />
pneumonia. Cases usually occur dur<strong>in</strong>g an epidemic, which may<br />
give the clue to diagnosis. A characteristic feature is the autoimmune<br />
haemolytic anaemia caused by the presence of cold agglut<strong>in</strong><strong>in</strong>s. Other<br />
extrapulmonary features <strong>in</strong>clude erythema multiforme, myopericarditis<br />
and men<strong>in</strong>goencephalitis. Diagnosis is often made <strong>in</strong> retrospect via<br />
detection of a ris<strong>in</strong>g antibody titre. If mycoplasma <strong>in</strong>fection is suspected<br />
on cl<strong>in</strong>ical grounds, a macrolide should be commenced empirically.<br />
A 25-year-old air-condition<strong>in</strong>g technician, who suffered from flu-like<br />
symptoms a week ago, has developed a dry cough. His chest radiograph<br />
shows multilobar shadow<strong>in</strong>g. Blood tests show hyponatraemia<br />
and lymphopenia. Ur<strong>in</strong>alysis reveals haematuria.<br />
Legionella pneumophila is a rare cause of atypical community pneumonia.<br />
Cases may occur sporadically, although outbreaks associated with <strong>in</strong>fected<br />
air-condition<strong>in</strong>g systems are well recognized. The patient often compla<strong>in</strong>s<br />
of a preced<strong>in</strong>g flu-like illness before frank lower respiratory symptoms,<br />
e.g. dry cough and dyspnoea. Other features such as hyponatraemia and<br />
lymphopenia may assist <strong>in</strong> diagnosis, which can be performed rapidly by<br />
test<strong>in</strong>g for the presence of legionella antigen <strong>in</strong> the ur<strong>in</strong>e (high sensitivity<br />
and specificity). Simple prevention measures such as adequate chlor<strong>in</strong>ation<br />
of the water supply are important to prevent outbreaks.<br />
13 Haemoptysis<br />
Answers: I G E A K<br />
I<br />
A 65-year-old smoker presents with shortness of breath, gallop<br />
rhythm and production of p<strong>in</strong>k frothy sputum.<br />
This is the presentation of pulmonary oedema secondary to left ventricular<br />
failure as evidenced by the other cardiac signs, e.g. <strong>in</strong>creased JVP,<br />
gallop rhythm. In this patient the most likely cause is ischaemic heart