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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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Haemoptysis – answers 39<br />

and Mycoplasma spp., if psittacosis is suspected, treatment should be<br />

commenced with a macrolide antibiotic.<br />

C<br />

H<br />

A<br />

A 40-year-old man with HIV presents with fever, dry cough, weight<br />

loss and exertional dyspnoea.<br />

This is a presentation of Pneumocystis car<strong>in</strong>ii <strong>in</strong>fection, which is a common<br />

complication of HIV <strong>in</strong>fection (AIDS-def<strong>in</strong><strong>in</strong>g illness). It may also<br />

occur as an opportunistic <strong>in</strong>fection <strong>in</strong> other immunocompromised<br />

patients such as those receiv<strong>in</strong>g immunosuppressive drugs and cancer<br />

chemotherapy.<br />

A 75-year-old man presents with headache, dry cough, anaemia and<br />

a sk<strong>in</strong> rash. Blood tests detect cold agglut<strong>in</strong><strong>in</strong>s.<br />

Mycoplasma <strong>in</strong>fection is the most common atypical cause of communityacquired<br />

pneumonia. Cases usually occur dur<strong>in</strong>g an epidemic, which may<br />

give the clue to diagnosis. A characteristic feature is the autoimmune<br />

haemolytic anaemia caused by the presence of cold agglut<strong>in</strong><strong>in</strong>s. Other<br />

extrapulmonary features <strong>in</strong>clude erythema multiforme, myopericarditis<br />

and men<strong>in</strong>goencephalitis. Diagnosis is often made <strong>in</strong> retrospect via<br />

detection of a ris<strong>in</strong>g antibody titre. If mycoplasma <strong>in</strong>fection is suspected<br />

on cl<strong>in</strong>ical grounds, a macrolide should be commenced empirically.<br />

A 25-year-old air-condition<strong>in</strong>g technician, who suffered from flu-like<br />

symptoms a week ago, has developed a dry cough. His chest radiograph<br />

shows multilobar shadow<strong>in</strong>g. Blood tests show hyponatraemia<br />

and lymphopenia. Ur<strong>in</strong>alysis reveals haematuria.<br />

Legionella pneumophila is a rare cause of atypical community pneumonia.<br />

Cases may occur sporadically, although outbreaks associated with <strong>in</strong>fected<br />

air-condition<strong>in</strong>g systems are well recognized. The patient often compla<strong>in</strong>s<br />

of a preced<strong>in</strong>g flu-like illness before frank lower respiratory symptoms,<br />

e.g. dry cough and dyspnoea. Other features such as hyponatraemia and<br />

lymphopenia may assist <strong>in</strong> diagnosis, which can be performed rapidly by<br />

test<strong>in</strong>g for the presence of legionella antigen <strong>in</strong> the ur<strong>in</strong>e (high sensitivity<br />

and specificity). Simple prevention measures such as adequate chlor<strong>in</strong>ation<br />

of the water supply are important to prevent outbreaks.<br />

13 Haemoptysis<br />

Answers: I G E A K<br />

I<br />

A 65-year-old smoker presents with shortness of breath, gallop<br />

rhythm and production of p<strong>in</strong>k frothy sputum.<br />

This is the presentation of pulmonary oedema secondary to left ventricular<br />

failure as evidenced by the other cardiac signs, e.g. <strong>in</strong>creased JVP,<br />

gallop rhythm. In this patient the most likely cause is ischaemic heart

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