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EMQs in Clinical Medicine.pdf - Peshawar Medical College

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Chest radiograph pathology – answers 41<br />

is the term used to describe widespread TB through haematological<br />

dissem<strong>in</strong>ation. It carries a poor prognosis.<br />

K<br />

A 35-year-old bus<strong>in</strong>essman returns from a trip abroad and collapses<br />

at the airport with haemoptysis and pleuritic chest pa<strong>in</strong>. He has a<br />

s<strong>in</strong>us tachycardia and his ECG shows right axis deviation.<br />

This is a classic history of pulmonary embolus (PE), although <strong>in</strong> many<br />

cases not all these features may be present. Diagnosis relies on a high<br />

<strong>in</strong>dex of cl<strong>in</strong>ical suspicion together with tests such as ventilation–<br />

perfusion scann<strong>in</strong>g and pulmonary angiography (now commonly<br />

performed us<strong>in</strong>g spiral computed tomography). Other risk factors for<br />

PE <strong>in</strong>clude previous thromboembolic events, oral contraceptive pill,<br />

surgery (especially pelvic surgery), immobility and <strong>in</strong>herited<br />

thrombophilias.<br />

14 Chest radiograph pathology<br />

Answers: J M C F A<br />

J<br />

M<br />

C<br />

Multiple bilateral nodules between 0.5 and 5 cm <strong>in</strong> a former m<strong>in</strong>er<br />

with rheumatoid arthritis.<br />

Caplan’s syndrome is a pulmonary manifestation of rheumatoid arthritis<br />

(RA) which is characterized by the presence of pulmonary nodules. It<br />

typically occurs <strong>in</strong> patients with RA who are exposed to coal dust,<br />

although the granulomas can also appear <strong>in</strong> workers exposed to other<br />

dusts, e.g. silicosis and asbestos. Symptoms <strong>in</strong>clude cough, shortness of<br />

breath and haemoptysis.<br />

RA has several other respiratory manifestations/associations <strong>in</strong>clud<strong>in</strong>g<br />

fibros<strong>in</strong>g alveolitis, pleural effusions and, very rarely, obliterative<br />

bronchiolitis. RA can also affect the cricoarytenoid jo<strong>in</strong>ts lead<strong>in</strong>g to<br />

upper respiratory tract obstruction.<br />

Kerley B l<strong>in</strong>es, bat-w<strong>in</strong>g shadow<strong>in</strong>g, prom<strong>in</strong>ent upper lobe vessels,<br />

cardiomegaly.<br />

These f<strong>in</strong>d<strong>in</strong>gs are suggestive of acute left ventricular failure lead<strong>in</strong>g to<br />

pulmonary oedema. Kerley B l<strong>in</strong>es are often difficult to see <strong>in</strong> real life.<br />

Although right ventricular failure may present with cardiomegaly,<br />

pulmonary oedema does not occur.<br />

Trachea deviated to right, horizontal fissure and right hilum displaced<br />

upwards.<br />

These chest radiograph f<strong>in</strong>d<strong>in</strong>gs are characteristic of right upper lobe<br />

collapse. Try to f<strong>in</strong>d the horizontal fissure because its position is a good<br />

clue to the presence of volume loss. The horizontal fissure on the right<br />

lung should run from the middle of the right hilum and can be traced to

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