biomedical sciences research institute - Research - University of Ulster

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Bala P, Baldridge K, Benfenati E, Casalegno M, Maran U, Miroslaw L, Ostropytskyy V, Rasch K, Sild S, Schöne R and WilliamsN; Handbook of Research on Computational GRID Technologies for Life Sciences, Biomedicine and Healthcare,Editor: M. Cannataro, Chapter Title: UNICORE – a middleware for Life Sciences Grids, 2008 (to appear)Schöne R, Rasch K, Ostropytskyy V, Mix H, Romberg M; The Chemomentum Data Services - A flexible Solution forData Handling in UNICORE Proceedings of 4th UNICORE Summit 2008, Springer LNCS, Euro-Par 2008 Workshopproceedings (to appear)106
12. VISION SCIENCES RESEARCH GROUPRESEARCH STRATEGYThe Vision Science Research Group (VSRG) conducts investigations on the entire visual system, from the opticalelements of the eye: the cornea and lens to the retina and higher visual pathways. The underlying strategy is to studythe structural and functional aspects of the ocular elements and visual system and how these are applied to the studyof developmental, growth and ageing processes. The main research themes in the group can be divided into clinicaland basic (laboratory) science:Laboratory Sciences:Optics: the optics of the lens and cornea are studied using ray tracing analysis, aberrometry, optical coherencetomography to determine changes with ageing, as the eye focuses and after refractive surgery.Biomechanics//Finite Element Analysis: the elasticity of the cornea and sclera is being measured by modelling the eyeballas a pressure vessel. Finite element analysis is used to model the optical/mechanical processes to determine howmechanical properties can impact on optical quality.Biochemistry/Cell biology: the protein chemistry of the eye lens is being studied to determine how the proteindistributions are linked to refractive index of the lens and cell culture techniques are used to look at damage toDNA in the cells from optical elements of the eye.Immunology: Immunological work had involved investigations of the ocular surface using patient samples, ocular surfacecells and donor tissue to identify biomarkers for application in translational patient based research which involvesdiagnostic and therapeutic approaches. Present research concentrates on two ocular surface conditions: HerpesSimplex Virus infection of the ocular surface and dry eye.Psychophysics: Psychophysical studies are being used to study the higher visual pathways as well as applied toinvestigations of age-related disease conditions such as glaucoma.Imaging: This work is conducted in collaboration with colleagues from Computing and Engineering and encompassesprojects on iris imaging to determine immutable features for biometric identification as well as retinal imaging forimproved diagnosis of eye disease.Clinical Sciences:Paediatric vision/epidemiological studies: Refractive errors in Northern Irish schoolchildren are being investigated in amajor epidemiological study that is the first of its kind.Developmental anomalies: Studies are being conducted on the ocular and optical anomalies in Downs syndrome andin Albinism.Geriatric/low vision: The association between ageing and eye disease is well known and these studies include work onmacular degeneration, glaucoma and the ocular effects of Alzheimer’s disease.Sports Vision: investigations are concerned with the effect of binocular vision on sports performance and how this canbe improved in a variety of different sports.Dyslexia: the effects of contrast and colour on reading, writing and learning ability are being investigated to comparevalidity of analytical methods and to determine the best methods of analysis, diagnosis and treatment for the childrenand adults who present with reading and writing difficulties.107
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Publications:Bigot S, Lucas L, Morr
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Publications:Barnes CA, O’Hagan B
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We also measure the genotoxic effec
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6. CANCER AND AGEING RESEARCH GROUP
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Professor Anthony P McHaleProfessor
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Professor Stephanie McKeownProfesso
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an Alzheimer Research Trust collabo
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JM, Waugh DJJ; Dexamethasone potent
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have wider applications in vivo, in
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Inter-relationships between diet an
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Flatt PR; Effective surgical treatm
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These areas are the subject of seve
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Dr YHA Abdel-WahabSenior Lecturer i
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Dr VA GaultLecturer in Molecular Bi
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McClean PL, Irwin N, Hunter K, Gaul
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Publications:Duffy NA, Green BD, Ir
Page 58 and 59: 8. MICROBIOLOGY AND BIOTECHNOLOGYRE
Page 60 and 61: Publications:Graham RJL, Graham C,
Page 62 and 63: analyses. However there is still a
Page 64 and 65: Plessas S, Bekatorou A, Koutinas AA
Page 66 and 67: Biochemical studies/ viral evasion
Page 68 and 69: Dr Stephen McCleanLecturer in Prote
Page 70 and 71: environmental remediation and as ro
Page 72 and 73: 9. NORTHERN IRELAND CENTRE FOR FOOD
Page 74 and 75: 26-28 Sept 2007: International Seaf
Page 76 and 77: Dr Barnes has developed expertise i
Page 78 and 79: Dr Alison GallagherSenior Lecturer
Page 80 and 81: In addition, results of a pilot stu
Page 82 and 83: Dr Maeve KerrResearch AssociateCont
Page 84 and 85: Memberships of External Committees/
Page 86 and 87: Indicators of Esteem:Professor McNu
Page 88 and 89: were examined. The intervention and
Page 90 and 91: Within this work both short-term an
Page 92 and 93: micronutrient supplementation at a
Page 94 and 95: 10. STEM CELL & EPIGENETICS RESEARC
Page 96 and 97: Publications:Lees-Murdock DJ, Lau H
Page 98 and 99: Publications:Lees-Murdock DJ, Lau H
Page 100 and 101: 11. SYSTEMS BIOLOGY RESEARCH GROUPT
Page 102 and 103: Kravtsov V, Swain M, Schuster A, Du
Page 104 and 105: Dr Daniel BerrarLecturer in Biomedi
Page 106 and 107: Zhang et al; Incorporating Feature
Page 110 and 111: In addition there is a growing them
Page 112 and 113: Clinical work involves development
Page 114 and 115: In 2009 he was appointed Chairman o
Page 116 and 117: Stevenson TR, Goodall EA and Moore
Page 118 and 119: Dr Raymond BeirneLecturer in Optome
Page 120 and 121: Dr Julie McClellandLecturer in Opto
Page 122 and 123: Graham JE, Moore JE, Moore JE, McCl
Page 124 and 125: Research Staff:Dr David OrrSenior R
Page 126 and 127: Dr Victoria McGilliganResearch Asso
Page 128 and 129: 13. Externally Funded Projects duri
Page 130 and 131: Grant Holder Anderson, Prof RSFundi
Page 132 and 133: Funding Body Royal Irish AcademyAmo
Page 134 and 135: 14. BIOMEDICAL SCIENCES RESEARCH IN
Page 136 and 137: Student: Simon GenglerTitle: Effect
Page 138 and 139: Student: Anisha MazumdarTitle: Anal
Page 140 and 141: Student: Clare RyanTitle: How does
Page 142 and 143: CONGRATULATIONS TO THE FOLLOWING PO
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