biomedical sciences research institute - Research - University of Ulster

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In addition, results of a pilot study conducted with colleagues in the Western Health and Social Care Trust toinvestigate the effect of taking a multi vitamin supplement on renal function and nutrient status in dialysis patients inthe Trust over a three month period were published recently on the University of Ulster web site and on BBC andITV news sites and numerous Renal web news sites, indicating the impact this research has on patient health. It ishoped that this type of intervention may provide the evidence base required to introduce this type of regime intoclinical care in haemodialysis patients in Northern Ireland.DNA damaged Lymphocytes: Left: stained with ethidium bromide right: head and tail indicated.Dr Hannon-Fletcher is a Fellow of the Institute of Biomedical Sciences, a registered Biomedical Scientist with theHealth Professions Council (HPC), a Chartered Scientist with the Science Council, a Registered Nutritionist withthe Nutrition Society and a member of Diabetes UK. In addition, Mary is a member of the scientific and conferenceorganizing committee of the European Childhood Obesity Group 2009 ECOG meeting, to be held in Dublin inSeptember 2008. Mary has keen interest in research ethics and sits on the School of Biomedical Science ResearchEthics Committee and is a member of the HPSS Research Ethical Committees, Northern Ireland (OREC NI).Publications:Hannon-Fletcher MP, Barnett YA; Lymphocyte cytochrome P450 expression: inducibility studies in male Wistar rats;British Journal of Biomedical Sciences, 65: 1-6, 2008McCaffrey TA, Rennie KL, Kerr MA, Wallace JM, Hannon-Fletcher MP, Coward WA, Jebb SA, Livingstone MB; Energydensity of the diet and change in body fatness from childhood to adolescence: is there a relation? American Journalof Clinical Nutrition, 87: 1230-1237, 2008Dr Geraldine HoriganResearch AssociateContact Details:T: +44 (0)28 70323516gb.horigan@ulster.ac.ukDr Horigan’s has been part of NICHE since 2002 and her main research interests are gene-nutrient interactionsin homocysteine metabolism, particularly the interaction between riboflavin the C677T polymorphism inMethylenetetrahydrofolate reductase (MTHFR) and blood pressure. Dietary requirements for vitamin D, bone healthand human intervention studies.Dr Horigan’s research activities include investigating vitamin D status in Irish adults in collaboration with UniversityCollege Cork. This large intervention study funded by the Food Standards Agency examined the intake of vitamin Drequired to prevent seasonal vitamin D deficiency in adults aged 20-85 years.Dr Horigan is currently a Research Associate involved in the Trinity Ulster and Department of Agriculture (TUDA)study one of three studies to be undertaken as part of a large cross-border collaborative project, TUDA is an78
observational study of 6000 patients recruited from both the North and South of Ireland with early evidence ofAlzheimer’s disease, osteoporosis and CVD. This research aims to provide information on current dietary trends,nutrigenomic and lifestyle information. As part of this project Dr Horigan will be involved in recruiting 2000hypertensive patients.Dr Horigan is a Member of: The Nutrition Society, UK; the National Association of Phlebotomists (NAP) (NAPapproved venipuncture (adult) trainer).Publications:Cashman K, Hill T, Lucey A, Taylor N, Seamans K, Muldowney S, Fitzgerald A, Flynn A, Barnes M, Horigan G, Bonham M,Duffy E, Strain JJ, Wallace J, & Kiely M; Estimation of the dietary requirement for vitamin D in healthy adults;American Journal of Clinical Nutrition, 88: 1535-1542, 2008Dickey W, Ward M, Whittle C, Kelly M, Pentieva K, Horigan G, Patton S & McNulty H; Homocysteine and relatedB-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery; Scandinavian Journal ofGastroenterology, 43: 682-688, 2008Dr Mary KellyResearch AssociateContact Details:T: +44 (0)28 70323969mt.kelly@ulster.ac.ukDr Mary Kelly completed her honours degree in Human Nutrition at the University of Ulster, and continued her studiesthere by completing a Masters of Research degree, before undertaking a PhD in the area of obesity research.Dr Kelly has been a part of NICHE since October 2005 and her main research interests are in the areas of appetite,satiety, the control of food intake and dietary factors influencing overweight and obesity. Dr Kelly has previouslyworked on industry-funded studies which have evaluated the effects of oligofructose enriched inulin on satiety,food intake, blood lipids and satiety hormones. She has also worked on a Food Standards Agency funded projectinvestigating the contribution made by food portion size to food and energy intake.Dr Kelly has recently been appointed as Lecturer in Human Nutrition where she will contribute to teaching andassessment in taught programmes within NICHE as well as being actively involved in working as part of a largemultidisciplinary research team in the Nutrition and Bone Health Research Unit.Publications:Kelly MT, Rennie KL, Wallace JMW, Robson PJ, Welch RW, Hannon-Fletcher MP and Livingstone MBE; Associationsbetween the portion sizes of food groups consumed and measures of adiposity in the British National Diet andNutrition Survey; British Journal of Nutrition (in press)Kelly MT, Wallace JM, Robson PJ, Rennie KL, Welch RW, Hannon-Fletcher MP, Brennan S, Fletcher A and LivingstoneMBE; Increased portion size leads to a sustained increase in energy intake over 4 days in normal weight and overweightmen and women; British Journal of Nutrition (in press)79
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Publications:Bigot S, Lucas L, Morr
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Publications:Barnes CA, O’Hagan B
Page 30 and 31: We also measure the genotoxic effec
Page 32 and 33: 6. CANCER AND AGEING RESEARCH GROUP
Page 34 and 35: Professor Anthony P McHaleProfessor
Page 36 and 37: Professor Stephanie McKeownProfesso
Page 38 and 39: an Alzheimer Research Trust collabo
Page 40 and 41: JM, Waugh DJJ; Dexamethasone potent
Page 42 and 43: have wider applications in vivo, in
Page 44 and 45: Inter-relationships between diet an
Page 46 and 47: Flatt PR; Effective surgical treatm
Page 48 and 49: These areas are the subject of seve
Page 50 and 51: Dr YHA Abdel-WahabSenior Lecturer i
Page 52 and 53: Dr VA GaultLecturer in Molecular Bi
Page 54 and 55: McClean PL, Irwin N, Hunter K, Gaul
Page 56 and 57: Publications:Duffy NA, Green BD, Ir
Page 58 and 59: 8. MICROBIOLOGY AND BIOTECHNOLOGYRE
Page 60 and 61: Publications:Graham RJL, Graham C,
Page 62 and 63: analyses. However there is still a
Page 64 and 65: Plessas S, Bekatorou A, Koutinas AA
Page 66 and 67: Biochemical studies/ viral evasion
Page 68 and 69: Dr Stephen McCleanLecturer in Prote
Page 70 and 71: environmental remediation and as ro
Page 72 and 73: 9. NORTHERN IRELAND CENTRE FOR FOOD
Page 74 and 75: 26-28 Sept 2007: International Seaf
Page 76 and 77: Dr Barnes has developed expertise i
Page 78 and 79: Dr Alison GallagherSenior Lecturer
Page 82 and 83: Dr Maeve KerrResearch AssociateCont
Page 84 and 85: Memberships of External Committees/
Page 86 and 87: Indicators of Esteem:Professor McNu
Page 88 and 89: were examined. The intervention and
Page 90 and 91: Within this work both short-term an
Page 92 and 93: micronutrient supplementation at a
Page 94 and 95: 10. STEM CELL & EPIGENETICS RESEARC
Page 96 and 97: Publications:Lees-Murdock DJ, Lau H
Page 98 and 99: Publications:Lees-Murdock DJ, Lau H
Page 100 and 101: 11. SYSTEMS BIOLOGY RESEARCH GROUPT
Page 102 and 103: Kravtsov V, Swain M, Schuster A, Du
Page 104 and 105: Dr Daniel BerrarLecturer in Biomedi
Page 106 and 107: Zhang et al; Incorporating Feature
Page 108 and 109: Bala P, Baldridge K, Benfenati E, C
Page 110 and 111: In addition there is a growing them
Page 112 and 113: Clinical work involves development
Page 114 and 115: In 2009 he was appointed Chairman o
Page 116 and 117: Stevenson TR, Goodall EA and Moore
Page 118 and 119: Dr Raymond BeirneLecturer in Optome
Page 120 and 121: Dr Julie McClellandLecturer in Opto
Page 122 and 123: Graham JE, Moore JE, Moore JE, McCl
Page 124 and 125: Research Staff:Dr David OrrSenior R
Page 126 and 127: Dr Victoria McGilliganResearch Asso
Page 128 and 129: 13. Externally Funded Projects duri
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Grant Holder Anderson, Prof RSFundi
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Funding Body Royal Irish AcademyAmo
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14. BIOMEDICAL SCIENCES RESEARCH IN
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Student: Simon GenglerTitle: Effect
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Student: Anisha MazumdarTitle: Anal
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Student: Clare RyanTitle: How does
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CONGRATULATIONS TO THE FOLLOWING PO
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