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biomedical sciences research institute - Research - University of Ulster

biomedical sciences research institute - Research - University of Ulster

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He has trained a large number <strong>of</strong> other users in the use <strong>of</strong> optical and electron microscopy to the point where theyare capable <strong>of</strong> using the instrumentation unsupervised or with minimal supervision.Dr O’Hagan’s first doctoral <strong>research</strong> student has recently finished her program <strong>of</strong> work and is awaiting a viva vocein the near future.Project collaborations:In addition to the ongoing development <strong>of</strong> biological cryo dual beam microscopy, Dr O’Hagan has been closelyinvolved in a number <strong>of</strong> other <strong>research</strong> projects within <strong>Ulster</strong> <strong>University</strong>, as well as collaborations with externalcompanies and institutions. These include the following:• Transmission electron microscopy <strong>of</strong> Nanotube structure (NI Bioengineering Centre - NIBEC).• Cryo-Dualbeam microscopy <strong>of</strong> osteoblast response to nanogrooved substrates. (<strong>University</strong> Nijmegen MedicalCentre, joint publication pending).• FIB nano-machining <strong>of</strong> AFM probe tips (Yael Dror, Oxford).• Cryo FIB, variable pressure ESEM Mitochondrial imaging. (<strong>University</strong> <strong>of</strong> Leicester, joint publication pending).• Temperature variation in SEM chamber during cryo operation (NIBEC).• TEM polymer structure and formation (Chemistry at Queens <strong>University</strong>).• Assistance with Nanotoxicology <strong>research</strong> (NanoInteract).• Assistance with fat emulsion <strong>research</strong> (CAST award with Unilever <strong>Research</strong>, Vlaardigan).• Assistance with investigations into bacterial adhesion to cells (CAST award with Unilever <strong>Research</strong>, PortSunlight).• Preliminary imaging <strong>of</strong> oil bearing rock core samples. (collaboration with Corex).Fig. 1Cryo Dual beam cross section through malariainfected bloodFig. 2Deconvolved multi-fluorescence image <strong>of</strong>mammalian cell25

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