biomedical sciences research institute - Research - University of Ulster

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Dr Alison GallagherSenior Lecturer in Biomedical Sciences (Human Nutrition)Contact Details:T: +44 (0)28 70323178am.gallagher@ulster.ac.ukDr Gallagher is a Registered Public Health Nutritionist and her current research interests include: investigation of therisk factors for development of disease; health effects of plans and plant components; physical activity and health.Development of risk factors for diseaseDr Gallagher has a longstanding involvement with the Young Hearts Project, a longitudinal investigation of risk factorsfor CVD, obesity and bone health which has provided a valuable dataset on diet, lifestyle and health from adolescenceto early adulthood in a representative sample of individuals from Northern Ireland. In the present reporting periodwork on B-vitamins and bone health and on the relationship between dietary glycaemic index and risk factors formetabolic syndrome were presented at the Nutrition Society Summer meeting. In addition from this data set werecently showed that increased arterial stiffness in young adult women (but not in men) is associated with increasedrisk of metabolic syndrome traits (Ferreira et al. 2007).Health effects of plants and plant componentsDr Gallagher’s early research work focussed on the evaluation of traditional remedies for diabetes. Work undertakenin collaboration with Strathclyde Institute of Pharmacy and Biomedical Sciences on galegine (derived from the herbalGalegine officinalis) and weight loss was published during this reporting period (Mooney et al. 2008). Dr Gallagher’scurrent research interests in this area include: health impact of dietary salicylates – in particular colorectal cancerprevention; the impact of bioactive components on satiety (including a consultancy project with ORAFTI); and healtheffects of modulating postprandial responses.Nutrition, physical activity and healthDr Gallagher’s research interest in this area of physical activity has more recently involved the evaluation ofintervention programmes to address obesity, including work with Community Sports Development, Derry CityCouncil to evaluate a school-based nutrition and physical activity intervention programme (with MP Bonham andfunded by Northern Ireland Chest Heart and Stroke); a long-term physical activity intervention in overweight/obese adults (with a DEL-funded PhD student T Morgan), and commencement of an evaluation of an interventionprogramme in older people (with EEA Simpson, Psychology).Dr Christopher GillLecturerContact details:T: +44 (0)28 70323181c.gill@ulster.ac.ukDr Gill’s research primarily focuses on the effect of diet on cancer, with specific interests in dietary componentsand colorectal cancer (especially phytochemicals in fruits, vegetables and seaweed including, brasscia, olive oil, andberries).Dr Gill also has a specific interest in gut microflora, faecal water toxicity (the aqueous phase of human faeces) andthe implications for colon cancer risk. Dr Gill’s research utilises cell modelling in conjunction with animal and human76
dietary intervention studies to identify potential mechanisms of action. He is currently a member of the scientificadvisory board for the Nordforsk Nordic Centre of Excellence Food and Health Initiative and the Danish PeerReview College.Publications:McCann MJ, Gill CI, Linton T, Berrar D, McGlynn H, Rowland IR; Enterolactone restricts the proliferation of theLNCaP human prostate cancer cell line in vitro; Mol Nutr Food Res, 52: 567-580, 2008Hashim YZ, Rowland IR, McGlynn H, Servili M, Selvaggini R, Taticchi A, Esposto S, Montedoro G, Kaisalo L, Wähälä K,Gill CI. Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro;International Journal of Cancer, 122: 495-500, 2008MacArtain P, Gill CI, Brooks M, Campbell R, Rowland IR; Nutritional value of edible seaweeds; Nutrition Reviews, 65:535-543, 2007Dr Mary Hannon-FletcherLecturer in Cellular PathologyContact Details:T: +44 (0)28 70323247mp.hannon@ulster.ac.ukDr Hannon-Fletcher’s research focuses on Human Nutrition observational, case-controlled and intervention studiesin disease (clinical settings) and in healthy groups. Of particular interest is oxidative stress measured by blood levelsof antioxidants and macromolecule damage (DNA, lipid and carbohydrate) in Type 1 diabetes, renal disease andhealthy control groups. This research also focuses on dietary intake (using food diaries and FFQ) and the relationshipbetween the intake of micro- and macronutrients and their effect on oxidative stress in health and disease.Current research focuses levels of DNA damage and oxidative stress in type 1 diabetes, and was invited to presenther work on ′Nutritional intake and oxidative stress in type 1 diabetes, to the Research and Development office,Endocrinology, Diabetes and Nutrition, Meeting in Coleraine 12 th October 2007, and presented a poster at theDiabetes UK, Professional Conference, Glasgow March 2008: Title: dietary intake in males with type 1 diabetes: arecurrent recommendations adequate?This research is of great interest to individuals with Type 1 diabetes and policy makers alike as it brings new informationon the impact of the diet and disease progression.Multivitamin supplements77
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Publications:Bigot S, Lucas L, Morr
Page 28 and 29: Publications:Barnes CA, O’Hagan B
Page 30 and 31: We also measure the genotoxic effec
Page 32 and 33: 6. CANCER AND AGEING RESEARCH GROUP
Page 34 and 35: Professor Anthony P McHaleProfessor
Page 36 and 37: Professor Stephanie McKeownProfesso
Page 38 and 39: an Alzheimer Research Trust collabo
Page 40 and 41: JM, Waugh DJJ; Dexamethasone potent
Page 42 and 43: have wider applications in vivo, in
Page 44 and 45: Inter-relationships between diet an
Page 46 and 47: Flatt PR; Effective surgical treatm
Page 48 and 49: These areas are the subject of seve
Page 50 and 51: Dr YHA Abdel-WahabSenior Lecturer i
Page 52 and 53: Dr VA GaultLecturer in Molecular Bi
Page 54 and 55: McClean PL, Irwin N, Hunter K, Gaul
Page 56 and 57: Publications:Duffy NA, Green BD, Ir
Page 58 and 59: 8. MICROBIOLOGY AND BIOTECHNOLOGYRE
Page 60 and 61: Publications:Graham RJL, Graham C,
Page 62 and 63: analyses. However there is still a
Page 64 and 65: Plessas S, Bekatorou A, Koutinas AA
Page 66 and 67: Biochemical studies/ viral evasion
Page 68 and 69: Dr Stephen McCleanLecturer in Prote
Page 70 and 71: environmental remediation and as ro
Page 72 and 73: 9. NORTHERN IRELAND CENTRE FOR FOOD
Page 74 and 75: 26-28 Sept 2007: International Seaf
Page 76 and 77: Dr Barnes has developed expertise i
Page 80 and 81: In addition, results of a pilot stu
Page 82 and 83: Dr Maeve KerrResearch AssociateCont
Page 84 and 85: Memberships of External Committees/
Page 86 and 87: Indicators of Esteem:Professor McNu
Page 88 and 89: were examined. The intervention and
Page 90 and 91: Within this work both short-term an
Page 92 and 93: micronutrient supplementation at a
Page 94 and 95: 10. STEM CELL & EPIGENETICS RESEARC
Page 96 and 97: Publications:Lees-Murdock DJ, Lau H
Page 98 and 99: Publications:Lees-Murdock DJ, Lau H
Page 100 and 101: 11. SYSTEMS BIOLOGY RESEARCH GROUPT
Page 102 and 103: Kravtsov V, Swain M, Schuster A, Du
Page 104 and 105: Dr Daniel BerrarLecturer in Biomedi
Page 106 and 107: Zhang et al; Incorporating Feature
Page 108 and 109: Bala P, Baldridge K, Benfenati E, C
Page 110 and 111: In addition there is a growing them
Page 112 and 113: Clinical work involves development
Page 114 and 115: In 2009 he was appointed Chairman o
Page 116 and 117: Stevenson TR, Goodall EA and Moore
Page 118 and 119: Dr Raymond BeirneLecturer in Optome
Page 120 and 121: Dr Julie McClellandLecturer in Opto
Page 122 and 123: Graham JE, Moore JE, Moore JE, McCl
Page 124 and 125: Research Staff:Dr David OrrSenior R
Page 126 and 127: Dr Victoria McGilliganResearch Asso
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13. Externally Funded Projects duri
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Grant Holder Anderson, Prof RSFundi
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Funding Body Royal Irish AcademyAmo
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14. BIOMEDICAL SCIENCES RESEARCH IN
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Student: Simon GenglerTitle: Effect
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Student: Anisha MazumdarTitle: Anal
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Student: Clare RyanTitle: How does
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CONGRATULATIONS TO THE FOLLOWING PO
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