biomedical sciences research institute - Research - University of Ulster

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In addition there is a growing theme in healthcare ethics and medical law as applied to eye care practice. The mainareas of research are Gillick competency and presumed consent.108
MEMBERS OF THE GROUP:Academic StaffProfessor Barbara Pierscionek, Group LeaderProfessor of Optometry & Vision ScienceContact details:T: +44 (0)28 70323293b.pierscionek@ulster.ac.ukProfessor Pierscionek works on the all aspects of the anterior eye involving a range of biochemical and biophysicalmethods.The optics of the lens and cornea have been studied using ray tracing and mathematical analysis (Eikonal equation) todetermine the refractive indices of these elements and how these varies across species and with age and development.The optics of the eye is dependent on its rheological (biomechanical properties) and Professor Pierscionek, incollaboration with Dr Widlicka from the Wroclaw University of Technology have developed a means of measuringthe elastic properties of the cornea and sclera in an intact eyeball. Elasticity of the lens is being modelled using FiniteElement Analysis and based on experimental results from simulations of lens shape change (as it occurs in the eye).The link between optics and mechanics of the eye and how these alter with age, disease and surgery is a new field ofresearch which will be increasingly important as a national and international priority given the ageing population andthe growing demand for refractive surgery.Finite element lens:The functional (optical and mechanical) features are being studied in parallel with structural investigations of lensprotein distributions and how these change with growth and ageing in a variety of species. This work has resulted inestablishing collaborations with Professor Michael Dunn and Dr Giuliano Elia from the Conway Institute in Dublin.The biochemical work also involves cell culture and investigations of the viability of DNA and chromosomal damagein response to chemical agents and quantum dots. This work is conducted in collaboration with Dr Wei Chen fromthe University of Texas in Arlington and with Dr Ronald Schachar from Pfizer. It will also involve collaborations withProfessors McLaughlin and Meenan from the Nanotechnology Research Institute. This work is aimed at having afuture impact on better understanding the structure/function relationships of the anterior eye structures and howthese alter with age and disease.Cell CulturesIn addition, Professor Pierscionek is investigating iris biometry in collaboration with Professor Scotney and Dr Morrowfrom Computing and Engineering to design improved methods of identification. This addresses the internationalpriority in the biometrics as applied to issues of security, both national and international.109
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Publications:Bigot S, Lucas L, Morr
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Publications:Barnes CA, O’Hagan B
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We also measure the genotoxic effec
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6. CANCER AND AGEING RESEARCH GROUP
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Professor Anthony P McHaleProfessor
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Professor Stephanie McKeownProfesso
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an Alzheimer Research Trust collabo
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JM, Waugh DJJ; Dexamethasone potent
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have wider applications in vivo, in
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Inter-relationships between diet an
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Flatt PR; Effective surgical treatm
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These areas are the subject of seve
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Dr YHA Abdel-WahabSenior Lecturer i
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Dr VA GaultLecturer in Molecular Bi
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McClean PL, Irwin N, Hunter K, Gaul
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Publications:Duffy NA, Green BD, Ir
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8. MICROBIOLOGY AND BIOTECHNOLOGYRE
Page 60 and 61: Publications:Graham RJL, Graham C,
Page 62 and 63: analyses. However there is still a
Page 64 and 65: Plessas S, Bekatorou A, Koutinas AA
Page 66 and 67: Biochemical studies/ viral evasion
Page 68 and 69: Dr Stephen McCleanLecturer in Prote
Page 70 and 71: environmental remediation and as ro
Page 72 and 73: 9. NORTHERN IRELAND CENTRE FOR FOOD
Page 74 and 75: 26-28 Sept 2007: International Seaf
Page 76 and 77: Dr Barnes has developed expertise i
Page 78 and 79: Dr Alison GallagherSenior Lecturer
Page 80 and 81: In addition, results of a pilot stu
Page 82 and 83: Dr Maeve KerrResearch AssociateCont
Page 84 and 85: Memberships of External Committees/
Page 86 and 87: Indicators of Esteem:Professor McNu
Page 88 and 89: were examined. The intervention and
Page 90 and 91: Within this work both short-term an
Page 92 and 93: micronutrient supplementation at a
Page 94 and 95: 10. STEM CELL & EPIGENETICS RESEARC
Page 96 and 97: Publications:Lees-Murdock DJ, Lau H
Page 98 and 99: Publications:Lees-Murdock DJ, Lau H
Page 100 and 101: 11. SYSTEMS BIOLOGY RESEARCH GROUPT
Page 102 and 103: Kravtsov V, Swain M, Schuster A, Du
Page 104 and 105: Dr Daniel BerrarLecturer in Biomedi
Page 106 and 107: Zhang et al; Incorporating Feature
Page 108 and 109: Bala P, Baldridge K, Benfenati E, C
Page 112 and 113: Clinical work involves development
Page 114 and 115: In 2009 he was appointed Chairman o
Page 116 and 117: Stevenson TR, Goodall EA and Moore
Page 118 and 119: Dr Raymond BeirneLecturer in Optome
Page 120 and 121: Dr Julie McClellandLecturer in Opto
Page 122 and 123: Graham JE, Moore JE, Moore JE, McCl
Page 124 and 125: Research Staff:Dr David OrrSenior R
Page 126 and 127: Dr Victoria McGilliganResearch Asso
Page 128 and 129: 13. Externally Funded Projects duri
Page 130 and 131: Grant Holder Anderson, Prof RSFundi
Page 132 and 133: Funding Body Royal Irish AcademyAmo
Page 134 and 135: 14. BIOMEDICAL SCIENCES RESEARCH IN
Page 136 and 137: Student: Simon GenglerTitle: Effect
Page 138 and 139: Student: Anisha MazumdarTitle: Anal
Page 140 and 141: Student: Clare RyanTitle: How does
Page 142 and 143: CONGRATULATIONS TO THE FOLLOWING PO
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