Dr Barnes has developed expertise in conducting human intervention studies and specialised laboratory techniques,particularly those associated with vitamin D metabolism and immune function. Her work has also focused on dietaryassessment, body composition and bone mineral density measurements.Other <strong>research</strong> interests include the effect <strong>of</strong> vitamin D status on immune conditions, particularly multiple sclerosis,vitamin D requirements during pregnancy and the influence <strong>of</strong> body composition on nutrient status.Dr Barnes is a Member <strong>of</strong>: The Nutrition Society, UK; the Multiple Sclerosis Society, UK; the <strong>Ulster</strong> ImmunologyGroup; and the Institute <strong>of</strong> Biomedical Science (Licentiate)Press releases:http://news.ulster.ac.uk/releases/2008/4014.htmlhttp://news.ulster.ac.uk/releases/2007/3543.htmlPublications:KD Cashman, TR Hill, AJ Lucey, N Taylor, KM Seamans, S Muldowney, AP FitzGerald, A Flynn, MS Barnes, G Horigan,MP Bonham, EM Duffy, JJ Strain, JMW Wallace & M Kiely; Estimation <strong>of</strong> the dietary requirement for Vitamin D inhealthy adults; American Journal <strong>of</strong> Clinical Nutrition, 88: 1535-1542, 2008MS Barnes, MP Bonham, PJ Robson, JJ Strain, AS Lowe-Strong, J Eaton-Evans, F Ginty & JMW Wallace; Assessment <strong>of</strong>25-hydroxyvitamin D and 1,25-dihydroxyvitamin D 3levels in male and female multiple sclerosis patients and healthycontrols; Multiple Sclerosis, 13: 670-672, 2007Dr Emeir DuffyLecturer in Human NutritionContact Details:T: +44 (0)28 70323543em.duffy@ulster.ac.ukDr Emeir Duffy’s main <strong>research</strong> interests include the effect <strong>of</strong> diet, specifically omega-3 fatty acids and vitamin D, onhealth and autoimmune diseases. She also has an interest in marine derived functional foods. During this reportingperiod Dr Duffy was a member <strong>of</strong> Seychelles Child Development Nutrition <strong>Research</strong> Group where she was activelyinvolved in the EU 6 th Framework funded project ‘PHIME’ investigating methyl mercury (MeHg) toxicity duringpregnancy. The PHIME consortium consists <strong>of</strong> 31 partners in 20 countries and will run over five years (2006-2011).In Europe and worldwide there is great speculation as to the effect <strong>of</strong> toxic metals, in particular MeHg, on childneurodevelopment. Results from these projects will provide information and guidance referring to health impactsassociated with consuming foodstuffs contaminated with toxic metals.Dr Duffy was a member <strong>of</strong> the vitamin D <strong>research</strong> group where she was actively involved in the Food Standards Agencyfunded projects ‘An investigation <strong>of</strong> the relative significance <strong>of</strong> both dietary sources and sunlight on vitamin D statusand/or functional markers, with particular emphasis on provision <strong>of</strong> scientific basis for dietary recommendations’ and‘Vitamin D status and associated health outcomes’. The results <strong>of</strong> the first study have been published and the secondstudy is still ongoing. Vitamin D deficiency is a major public health challenge facing the world and results from thesestudies will impact on public health strategies aimed at targeting this problem.In 2007, Dr Duffy formed partnership with 6 other institutions on the Island <strong>of</strong> Ireland to form the Marine FunctionalFoods <strong>Research</strong> Initiative Consortium <strong>of</strong> which she acts as the PI for the <strong>University</strong> <strong>of</strong> <strong>Ulster</strong>. This initiative is toestablish Ireland as a world-competitor in the area <strong>of</strong> marine functional foods and identify novel marine derived74
ioactives by enabling technological transfer between academia and industry. To further establish links with the Marineindustry and UU she was successful in being awarded a Fusion project and an Enterprise Ireland funded project toinvestiate the effect <strong>of</strong> a marine derived calcium supplement on bone health. Median term deliverables include theidentification <strong>of</strong> dietary compounds that demonstrate anti-cancer activity in vitro together with identifying beneficialeffects <strong>of</strong> marine-derived compounds on cancer and bone health with potential applications in functional foods.Dr Duffy was involved in a project funded by CAST, in conjunction with the LMC Northern Ireland, investigating theeffect <strong>of</strong> grass feeding on the omega-3 content <strong>of</strong> red meat produced in Northern Ireland. Medium term deliverablesinclude the identification <strong>of</strong> grass-finished red meat as a valuable source <strong>of</strong> dietary omega-3 bringing added valueto Northern Irish produced beef and lamb. Dr Duffy was actively involved in the Lupus <strong>Research</strong> Group NorthernIreland and a committee member <strong>of</strong> the <strong>Ulster</strong> Immunology Group (UIG). Awarded a DEL funded PhD to furtherinvestiate the effect <strong>of</strong> vitamin D on systemic lupus erythematosus. In October 2007, she formed part <strong>of</strong> the localorganising committee for the British Society <strong>of</strong> Immunology (BSI) 50 th Anniversary Symposium hosted by the UIG inBelfast.Publications:Bonham MP, Duffy EM, Robson PJ, Wallace JM, Myers GJ, Davidson PW, Clarkson TW, Shamlaye CF, Strain J, LivingstoneMB; Contribution <strong>of</strong> fish to intakes <strong>of</strong> micronutrients important for fetal development: a dietary survey <strong>of</strong> pregnantwomen in the Republic <strong>of</strong> Seychelles; Public Health Nutrition, 6: 1-9, 2008Bonham MP, Duffy EM, Wallace JM, Robson PJ, Myers GJ, Davidson PW, Clarkson TW, Shamlaye CF, Strain JJ; Habitual fishconsumption does not prevent a decrease in LCPUFA status in pregnant women (the Seychelles Child DevelopmentNutrition Study); Prostaglandins Leukot Essent Fatty Acids, 78: 343-350, 2008Davidson PW, Strain JJ, Myers GJ, Thurston SW, Bonham MP, Shamlaye CF, Stokes-Riner A, Wallace JM, Robson PJ,Duffy EM, Georger LA, Sloane-Reeves J, Cernichiari E, Canfield RL, Cox C, Huang LS, Janciuras J, Clarkson TW;Neurodevelopmental effects <strong>of</strong> maternal nutritional status and exposure to methylmercury from eating fish duringpregnancy; Neurotoxicology, 29: 767-775, 2008Cashman KD, Hill TR, Lucey AJ, Taylor N, Seamans KM, Muldowney S, Fitzgerald AP, Flynn A, Barnes MS, Horigan G,Bonham MP, Duffy EM, Strain JJ, Wallace JM, Kiely M; Estimation <strong>of</strong> the dietary requirement for vitamin D in healthyadults; American Journal <strong>of</strong> Clinical Nutrition, 88: 1535-1542, 2008Strain JJ, Davidson PW, Bonham MP, Duffy EM, Stokes-Riner A, Thurston SW, Wallace JM, Robson PJ, Shamlaye CF,Georger LA, Sloane-Reeves J, Cernichiari E, Canfield RL, Cox C, Huang LS, Janciuras J, Myers GJ, Clarkson TW;Associations <strong>of</strong> maternal long-chain polyunsaturated fatty acids, methyl mercury, and infant development in theSeychelles Child Development Nutrition Study; Neurotoxicology, 29: 776-782, 2008Wallace JM, Bonham MP, Strain J, Duffy EM, Robson PJ, Ward M, McNulty H, Davidson PW, Myers GJ, Shamlaye CF,Clarkson TW, Molloy AM, Scott JM, Ueland PM; Homocysteine concentration, related B vitamins, and betaine inpregnant women recruited to the Seychelles Child Development Study; American Journal <strong>of</strong> Clinical Nutrition, 87: 391-397, 2008Wright SA, O'Prey FM, McHenry MT, Leahey WJ, Devine AB, Duffy EM, Johnston DG, Finch MB, Bell AL, McVeigh GE.A randomised interventional trial <strong>of</strong> omega-3-polyunsaturated fatty acids on endothelial function and disease activityin systemic lupus erythematosus; Ann Rheum Dis, 67: 841-848, 200875
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Dr Victoria McGilliganResearch Asso
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13. Externally Funded Projects duri
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Grant Holder Anderson, Prof RSFundi
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Funding Body Royal Irish AcademyAmo
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14. BIOMEDICAL SCIENCES RESEARCH IN
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Student: Simon GenglerTitle: Effect
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Student: Anisha MazumdarTitle: Anal
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Student: Clare RyanTitle: How does
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CONGRATULATIONS TO THE FOLLOWING PO