In addition, results <strong>of</strong> a pilot study conducted with colleagues in the Western Health and Social Care Trust toinvestigate the effect <strong>of</strong> taking a multi vitamin supplement on renal function and nutrient status in dialysis patients inthe Trust over a three month period were published recently on the <strong>University</strong> <strong>of</strong> <strong>Ulster</strong> web site and on BBC andITV news sites and numerous Renal web news sites, indicating the impact this <strong>research</strong> has on patient health. It ishoped that this type <strong>of</strong> intervention may provide the evidence base required to introduce this type <strong>of</strong> regime intoclinical care in haemodialysis patients in Northern Ireland.DNA damaged Lymphocytes: Left: stained with ethidium bromide right: head and tail indicated.Dr Hannon-Fletcher is a Fellow <strong>of</strong> the Institute <strong>of</strong> Biomedical Sciences, a registered Biomedical Scientist with theHealth Pr<strong>of</strong>essions Council (HPC), a Chartered Scientist with the Science Council, a Registered Nutritionist withthe Nutrition Society and a member <strong>of</strong> Diabetes UK. In addition, Mary is a member <strong>of</strong> the scientific and conferenceorganizing committee <strong>of</strong> the European Childhood Obesity Group 2009 ECOG meeting, to be held in Dublin inSeptember 2008. Mary has keen interest in <strong>research</strong> ethics and sits on the School <strong>of</strong> Biomedical Science <strong>Research</strong>Ethics Committee and is a member <strong>of</strong> the HPSS <strong>Research</strong> Ethical Committees, Northern Ireland (OREC NI).Publications:Hannon-Fletcher MP, Barnett YA; Lymphocyte cytochrome P450 expression: inducibility studies in male Wistar rats;British Journal <strong>of</strong> Biomedical Sciences, 65: 1-6, 2008McCaffrey TA, Rennie KL, Kerr MA, Wallace JM, Hannon-Fletcher MP, Coward WA, Jebb SA, Livingstone MB; Energydensity <strong>of</strong> the diet and change in body fatness from childhood to adolescence: is there a relation? American Journal<strong>of</strong> Clinical Nutrition, 87: 1230-1237, 2008Dr Geraldine Horigan<strong>Research</strong> AssociateContact Details:T: +44 (0)28 70323516gb.horigan@ulster.ac.ukDr Horigan’s has been part <strong>of</strong> NICHE since 2002 and her main <strong>research</strong> interests are gene-nutrient interactionsin homocysteine metabolism, particularly the interaction between rib<strong>of</strong>lavin the C677T polymorphism inMethylenetetrahydr<strong>of</strong>olate reductase (MTHFR) and blood pressure. Dietary requirements for vitamin D, bone healthand human intervention studies.Dr Horigan’s <strong>research</strong> activities include investigating vitamin D status in Irish adults in collaboration with <strong>University</strong>College Cork. This large intervention study funded by the Food Standards Agency examined the intake <strong>of</strong> vitamin Drequired to prevent seasonal vitamin D deficiency in adults aged 20-85 years.Dr Horigan is currently a <strong>Research</strong> Associate involved in the Trinity <strong>Ulster</strong> and Department <strong>of</strong> Agriculture (TUDA)study one <strong>of</strong> three studies to be undertaken as part <strong>of</strong> a large cross-border collaborative project, TUDA is an78
observational study <strong>of</strong> 6000 patients recruited from both the North and South <strong>of</strong> Ireland with early evidence <strong>of</strong>Alzheimer’s disease, osteoporosis and CVD. This <strong>research</strong> aims to provide information on current dietary trends,nutrigenomic and lifestyle information. As part <strong>of</strong> this project Dr Horigan will be involved in recruiting 2000hypertensive patients.Dr Horigan is a Member <strong>of</strong>: The Nutrition Society, UK; the National Association <strong>of</strong> Phlebotomists (NAP) (NAPapproved venipuncture (adult) trainer).Publications:Cashman K, Hill T, Lucey A, Taylor N, Seamans K, Muldowney S, Fitzgerald A, Flynn A, Barnes M, Horigan G, Bonham M,Duffy E, Strain JJ, Wallace J, & Kiely M; Estimation <strong>of</strong> the dietary requirement for vitamin D in healthy adults;American Journal <strong>of</strong> Clinical Nutrition, 88: 1535-1542, 2008Dickey W, Ward M, Whittle C, Kelly M, Pentieva K, Horigan G, Patton S & McNulty H; Homocysteine and relatedB-vitamin status in coeliac disease: Effects <strong>of</strong> gluten exclusion and histological recovery; Scandinavian Journal <strong>of</strong>Gastroenterology, 43: 682-688, 2008Dr Mary Kelly<strong>Research</strong> AssociateContact Details:T: +44 (0)28 70323969mt.kelly@ulster.ac.ukDr Mary Kelly completed her honours degree in Human Nutrition at the <strong>University</strong> <strong>of</strong> <strong>Ulster</strong>, and continued her studiesthere by completing a Masters <strong>of</strong> <strong>Research</strong> degree, before undertaking a PhD in the area <strong>of</strong> obesity <strong>research</strong>.Dr Kelly has been a part <strong>of</strong> NICHE since October 2005 and her main <strong>research</strong> interests are in the areas <strong>of</strong> appetite,satiety, the control <strong>of</strong> food intake and dietary factors influencing overweight and obesity. Dr Kelly has previouslyworked on industry-funded studies which have evaluated the effects <strong>of</strong> olig<strong>of</strong>ructose enriched inulin on satiety,food intake, blood lipids and satiety hormones. She has also worked on a Food Standards Agency funded projectinvestigating the contribution made by food portion size to food and energy intake.Dr Kelly has recently been appointed as Lecturer in Human Nutrition where she will contribute to teaching andassessment in taught programmes within NICHE as well as being actively involved in working as part <strong>of</strong> a largemultidisciplinary <strong>research</strong> team in the Nutrition and Bone Health <strong>Research</strong> Unit.Publications:Kelly MT, Rennie KL, Wallace JMW, Robson PJ, Welch RW, Hannon-Fletcher MP and Livingstone MBE; Associationsbetween the portion sizes <strong>of</strong> food groups consumed and measures <strong>of</strong> adiposity in the British National Diet andNutrition Survey; British Journal <strong>of</strong> Nutrition (in press)Kelly MT, Wallace JM, Robson PJ, Rennie KL, Welch RW, Hannon-Fletcher MP, Brennan S, Fletcher A and LivingstoneMBE; Increased portion size leads to a sustained increase in energy intake over 4 days in normal weight and overweightmen and women; British Journal <strong>of</strong> Nutrition (in press)79
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Publications:Bigot S, Lucas L, Morr
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Publications:Barnes CA, O’Hagan B
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Grant Holder Anderson, Prof RSFundi
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Funding Body Royal Irish AcademyAmo
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14. BIOMEDICAL SCIENCES RESEARCH IN
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Student: Simon GenglerTitle: Effect
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Student: Anisha MazumdarTitle: Anal
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Student: Clare RyanTitle: How does
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CONGRATULATIONS TO THE FOLLOWING PO