Dr Alison GallagherSenior Lecturer in Biomedical Sciences (Human Nutrition)Contact Details:T: +44 (0)28 70323178am.gallagher@ulster.ac.ukDr Gallagher is a Registered Public Health Nutritionist and her current <strong>research</strong> interests include: investigation <strong>of</strong> therisk factors for development <strong>of</strong> disease; health effects <strong>of</strong> plans and plant components; physical activity and health.Development <strong>of</strong> risk factors for diseaseDr Gallagher has a longstanding involvement with the Young Hearts Project, a longitudinal investigation <strong>of</strong> risk factorsfor CVD, obesity and bone health which has provided a valuable dataset on diet, lifestyle and health from adolescenceto early adulthood in a representative sample <strong>of</strong> individuals from Northern Ireland. In the present reporting periodwork on B-vitamins and bone health and on the relationship between dietary glycaemic index and risk factors formetabolic syndrome were presented at the Nutrition Society Summer meeting. In addition from this data set werecently showed that increased arterial stiffness in young adult women (but not in men) is associated with increasedrisk <strong>of</strong> metabolic syndrome traits (Ferreira et al. 2007).Health effects <strong>of</strong> plants and plant componentsDr Gallagher’s early <strong>research</strong> work focussed on the evaluation <strong>of</strong> traditional remedies for diabetes. Work undertakenin collaboration with Strathclyde Institute <strong>of</strong> Pharmacy and Biomedical Sciences on galegine (derived from the herbalGalegine <strong>of</strong>ficinalis) and weight loss was published during this reporting period (Mooney et al. 2008). Dr Gallagher’scurrent <strong>research</strong> interests in this area include: health impact <strong>of</strong> dietary salicylates – in particular colorectal cancerprevention; the impact <strong>of</strong> bioactive components on satiety (including a consultancy project with ORAFTI); and healtheffects <strong>of</strong> modulating postprandial responses.Nutrition, physical activity and healthDr Gallagher’s <strong>research</strong> interest in this area <strong>of</strong> physical activity has more recently involved the evaluation <strong>of</strong>intervention programmes to address obesity, including work with Community Sports Development, Derry CityCouncil to evaluate a school-based nutrition and physical activity intervention programme (with MP Bonham andfunded by Northern Ireland Chest Heart and Stroke); a long-term physical activity intervention in overweight/obese adults (with a DEL-funded PhD student T Morgan), and commencement <strong>of</strong> an evaluation <strong>of</strong> an interventionprogramme in older people (with EEA Simpson, Psychology).Dr Christopher GillLecturerContact details:T: +44 (0)28 70323181c.gill@ulster.ac.ukDr Gill’s <strong>research</strong> primarily focuses on the effect <strong>of</strong> diet on cancer, with specific interests in dietary componentsand colorectal cancer (especially phytochemicals in fruits, vegetables and seaweed including, brasscia, olive oil, andberries).Dr Gill also has a specific interest in gut micr<strong>of</strong>lora, faecal water toxicity (the aqueous phase <strong>of</strong> human faeces) andthe implications for colon cancer risk. Dr Gill’s <strong>research</strong> utilises cell modelling in conjunction with animal and human76
dietary intervention studies to identify potential mechanisms <strong>of</strong> action. He is currently a member <strong>of</strong> the scientificadvisory board for the Nordforsk Nordic Centre <strong>of</strong> Excellence Food and Health Initiative and the Danish PeerReview College.Publications:McCann MJ, Gill CI, Linton T, Berrar D, McGlynn H, Rowland IR; Enterolactone restricts the proliferation <strong>of</strong> theLNCaP human prostate cancer cell line in vitro; Mol Nutr Food Res, 52: 567-580, 2008Hashim YZ, Rowland IR, McGlynn H, Servili M, Selvaggini R, Taticchi A, Esposto S, Montedoro G, Kaisalo L, Wähälä K,Gill CI. Inhibitory effects <strong>of</strong> olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro;International Journal <strong>of</strong> Cancer, 122: 495-500, 2008MacArtain P, Gill CI, Brooks M, Campbell R, Rowland IR; Nutritional value <strong>of</strong> edible seaweeds; Nutrition Reviews, 65:535-543, 2007Dr Mary Hannon-FletcherLecturer in Cellular PathologyContact Details:T: +44 (0)28 70323247mp.hannon@ulster.ac.ukDr Hannon-Fletcher’s <strong>research</strong> focuses on Human Nutrition observational, case-controlled and intervention studiesin disease (clinical settings) and in healthy groups. Of particular interest is oxidative stress measured by blood levels<strong>of</strong> antioxidants and macromolecule damage (DNA, lipid and carbohydrate) in Type 1 diabetes, renal disease andhealthy control groups. This <strong>research</strong> also focuses on dietary intake (using food diaries and FFQ) and the relationshipbetween the intake <strong>of</strong> micro- and macronutrients and their effect on oxidative stress in health and disease.Current <strong>research</strong> focuses levels <strong>of</strong> DNA damage and oxidative stress in type 1 diabetes, and was invited to presenther work on ′Nutritional intake and oxidative stress in type 1 diabetes, to the <strong>Research</strong> and Development <strong>of</strong>fice,Endocrinology, Diabetes and Nutrition, Meeting in Coleraine 12 th October 2007, and presented a poster at theDiabetes UK, Pr<strong>of</strong>essional Conference, Glasgow March 2008: Title: dietary intake in males with type 1 diabetes: arecurrent recommendations adequate?This <strong>research</strong> is <strong>of</strong> great interest to individuals with Type 1 diabetes and policy makers alike as it brings new informationon the impact <strong>of</strong> the diet and disease progression.Multivitamin supplements77
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BIOMEDICAL SCIENCESRESEARCH INSTITU
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1 Foreword by the Pro Vice-Chancell
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2 Foreword by the Research Institut
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The BMSRI Research StructureThe BMS
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BMSRI Core FacilitiesContact: Karen
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of Metabolomics, pharmacy, nutritio
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BMSRI Academic Heads new Regional N
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4. BIOMEDICAL GENOMICS RESEARCH GRO
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Recent Funding Initiatives:C-TRIC:
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Dr Mateus Webba da SilvaLecturer in
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5. BIOIMAGING RESEARCH GROUPResearc
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developmental alterations that mani
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Grant Holder Anderson, Prof RSFundi
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Student: Simon GenglerTitle: Effect
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CONGRATULATIONS TO THE FOLLOWING PO