biomedical sciences research institute - Research - University of Ulster

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Inter-relationships between diet and diabetes/obesityAssessment of diet and lifestyle factors in gestational type 1 and type 2 diabetes. This research aims toassess what women with diabetes eat in relation to lifestyle and published dietary guidelines. A further element isassessing maternal diet and lifestyle factors in relation to gestational diabetes and pregnancy outcomes.The overall strategy of the Diabetes Research Group is:• to undertake and publish research of national and international status aimed at increasing knowledge of thepancreatic islets, endocrine control of nutrient homeostasis and both the pathophysiology and treatment ofdiabetes mellitus;• to exploit intellectual property and actively pursue technology transfer with the aim of helping to alleviate theworld-wide burden of diabetes and contributing to the prosperity and knowledge-based economy in NorthernIreland;• to provide a supportive and high quality training environment for research students and postdoctoral fellows tofacilitate the acquisition of knowledge, new skills, personal fulfillment and career progression;• to participate in productive national and international networks with Centres of Excellence for diabetesresearch and to actively contribute to the global diabetes community, through conferences and involvementwith organizations promoting research, understanding and well being of individuals with diabetes.Members of the GroupAcademic Staff:Group LeaderProfessor of Biological & Biomedical SciencesContact Details:T: +44 (0)28 70324419pr.flatt@ulster.ac.ukBrief Profile:BSc Hons and PhD from Aston University. Research Fellow at the University of Uppsala, Sweden (1978-80) beforetaking up an academic appointment at Surrey University in 1980 and current position as Professor of BiomedicalSciences in 1989. Professor Flatt is Head of the Diabetes Research Group, having served as Director of BiomedicalSciences Research Centre (1992-94) and Head of the School of Biomedical Sciences (1994-97).Professor Flatt is author of over 400 full scientific peer-reviewed papers on various aspects of diabetes and editorof 4 major diabetes research texts including New Antidiabetic Drugs (Smith-Gordon, 1990) and Nutrient Regulationof Insulin Secretion (Portland Press, 1992).He is founding Chairman (1991-) of the Islet Study Group of the European Association for the Study of Diabetes(EASD), Member of the EASD Council (1997-01), Scientific Secretary and Committee Member of Diabetes UK(1991-97; 2001-04) and member of the Grants Review Board of the Juvenile Diabetes Federation International(1996-99).Recipient: Mary Jane Kugal Award (1999) of Juvenile Diabetes Federation International, Biochemical Society Medal(2005), elected to membership of Royal Irish Academy (2006), University of Ulster Distinguished Senior ResearchFellowship (2006) and Diabetes UK Dorothy Hodgkin Award Lecturer (2008). Patent holder - academic co-founder42
and Chief Scientific Officer/Director of Diabetica Limited.Main Research interests:• Insulin secretion• pancreatic islet cell function and demise• antidiabetic drugs• gene therapy• brain and gut peptides• glucose homeostasis• insulinoma and obesity.Esteem:2007 Hodgkin Award presented at the Annual Professional Congress of Diabetes UKCommittees:Member of Diabetes UK Advisory CouncilMember of Diabetes UK Research CommitteeMember of Diabetes UK Research Advisory GroupMember of Diabetes UK Professional Advisory CouncilMember of Diabetes UK Science and Research CommitteeFounding Chairman European Association for Study of Diabetes (EASD) Islet Study GroupFounding Member of Islet Research European and Latin American NetworksMember of Executive of IRELAN Alfa NetworkChairman, scientific sessions at Diabetes UK, EASD and other International meetingsConsultant to Shering PloughInvited LecturesSeminar on Novel Approaches to Diabetes Therapy, Takeda Pharmaceuticals, Amsterdam, 2007Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM) Seminar Series Guest Lecture , Oxford, 2007Seminar on GIP Therapeutics and Diabetes, Boehringer Ingelheim Pharmaceutical Company, Biberach, Germany, 2007International Conference on Treatment and Prevention of Obesity, Copenhagen, 2007Seminar on Incretin Hormones and Diabetes, Organon Pharmaceutical Company, Oss, Netherlands, 2007Seminar on Therapeutic Gut Hormones, Novo Nordisk Ltd, Copenhagen, 2007Conference on New Approaches to Diabetes, Ipsen Pharmaceutical Company, Barcelona, 2007International Conference on Diabetes in Crisis, Dublin, 2007Diabetes UK Annual Professional Congress, Dorothy Hodgkin Lecture, Glasgow, 2008Diabetes UK Annual Professional Congress, Meet the Professor, Glasgow, 2008International Conference on Importance of Early Phase Insulin Release in Type 2 Diabetes, Tokyo, 2008International Conference on Diabetes Mellitus and Obesity, Taif, Saudi Arabia, 2008FEND (Federation of European Nurses in Diabetes) 13th Annual Conference, Rome, September, 2008Royal Society of Medicine Conference on From Bench to Patient: taking Diabetes into the 21st Century, London,October, 2008Publications:Abdel-Wahab YHA, Marenah L, Flatt PR and Conlon JM; Insulin-releasing properties of the temporin family ofantimicrobial peptides; Protein Pept. Letts, 14: 702-707, 2007Duffy NA, Green BD, Irwin N, Gault VA, McKillop AM, O’Harte FPM and Flatt PR; Effects of antidiabetic drugson dipeptidyl peptidase IV activity: Nateglinide is an inhibitor of DPP IV and augments the antidiabetic activity ofglucagon-like peptide-1; European Journal of Pharmacology, 568: 278-286, 200743
Page 1: BIOMEDICAL SCIENCESRESEARCH INSTITU
Page 4 and 5: 1 Foreword by the Pro Vice-Chancell
Page 6 and 7: 2 Foreword by the Research Institut
Page 8 and 9: The BMSRI Research StructureThe BMS
Page 10 and 11: BMSRI Core FacilitiesContact: Karen
Page 12 and 13: of Metabolomics, pharmacy, nutritio
Page 14 and 15: BMSRI Academic Heads new Regional N
Page 16 and 17: 4. BIOMEDICAL GENOMICS RESEARCH GRO
Page 18 and 19: Recent Funding Initiatives:C-TRIC:
Page 20 and 21: Dr Mateus Webba da SilvaLecturer in
Page 22 and 23: 5. BIOIMAGING RESEARCH GROUPResearc
Page 24 and 25: developmental alterations that mani
Page 26 and 27: Publications:Bigot S, Lucas L, Morr
Page 28 and 29: Publications:Barnes CA, O’Hagan B
Page 30 and 31: We also measure the genotoxic effec
Page 32 and 33: 6. CANCER AND AGEING RESEARCH GROUP
Page 34 and 35: Professor Anthony P McHaleProfessor
Page 36 and 37: Professor Stephanie McKeownProfesso
Page 38 and 39: an Alzheimer Research Trust collabo
Page 40 and 41: JM, Waugh DJJ; Dexamethasone potent
Page 42 and 43: have wider applications in vivo, in
Page 46 and 47: Flatt PR; Effective surgical treatm
Page 48 and 49: These areas are the subject of seve
Page 50 and 51: Dr YHA Abdel-WahabSenior Lecturer i
Page 52 and 53: Dr VA GaultLecturer in Molecular Bi
Page 54 and 55: McClean PL, Irwin N, Hunter K, Gaul
Page 56 and 57: Publications:Duffy NA, Green BD, Ir
Page 58 and 59: 8. MICROBIOLOGY AND BIOTECHNOLOGYRE
Page 60 and 61: Publications:Graham RJL, Graham C,
Page 62 and 63: analyses. However there is still a
Page 64 and 65: Plessas S, Bekatorou A, Koutinas AA
Page 66 and 67: Biochemical studies/ viral evasion
Page 68 and 69: Dr Stephen McCleanLecturer in Prote
Page 70 and 71: environmental remediation and as ro
Page 72 and 73: 9. NORTHERN IRELAND CENTRE FOR FOOD
Page 74 and 75: 26-28 Sept 2007: International Seaf
Page 76 and 77: Dr Barnes has developed expertise i
Page 78 and 79: Dr Alison GallagherSenior Lecturer
Page 80 and 81: In addition, results of a pilot stu
Page 82 and 83: Dr Maeve KerrResearch AssociateCont
Page 84 and 85: Memberships of External Committees/
Page 86 and 87: Indicators of Esteem:Professor McNu
Page 88 and 89: were examined. The intervention and
Page 90 and 91: Within this work both short-term an
Page 92 and 93: micronutrient supplementation at a
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10. STEM CELL & EPIGENETICS RESEARC
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Publications:Lees-Murdock DJ, Lau H
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Publications:Lees-Murdock DJ, Lau H
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11. SYSTEMS BIOLOGY RESEARCH GROUPT
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Kravtsov V, Swain M, Schuster A, Du
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Dr Daniel BerrarLecturer in Biomedi
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Zhang et al; Incorporating Feature
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Bala P, Baldridge K, Benfenati E, C
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In addition there is a growing them
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Clinical work involves development
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In 2009 he was appointed Chairman o
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Stevenson TR, Goodall EA and Moore
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Dr Raymond BeirneLecturer in Optome
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Dr Julie McClellandLecturer in Opto
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Graham JE, Moore JE, Moore JE, McCl
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Research Staff:Dr David OrrSenior R
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Dr Victoria McGilliganResearch Asso
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13. Externally Funded Projects duri
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Grant Holder Anderson, Prof RSFundi
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Funding Body Royal Irish AcademyAmo
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14. BIOMEDICAL SCIENCES RESEARCH IN
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Student: Simon GenglerTitle: Effect
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Student: Anisha MazumdarTitle: Anal
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Student: Clare RyanTitle: How does
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CONGRATULATIONS TO THE FOLLOWING PO
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