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2006 - UZ Leuven

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ventilation, lungs in HBD and CONTROL were preserved with a coldantegrade flush. In NHBD, unflushed grafts were explanted after 1 hof warm ischemia and 4 h of topical cooling in the cadaver. Graftperformance was evaluated during 1 h in an isolated ventilation andreperfusion model. Extravascular lung water content (EVLW) wascalculated. All data are reported as mean+/-SEM.Results: A significant autonomic storm was observed in HBD followingballoon inflation. During ex vivo assessment, pulmonary vascularresistance (PVR) at 60 min in HBD (2634+/-371 dynes cm(-5)) wassignificantly higher as compared with that of CONTROL and NHBD(1894+/-137 dynes s cm(-5) and 1268+/-111 dynes s cm(-5),respectively; p

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