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2006 - UZ Leuven

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distal protection from the Interceptor Filter System is effective andsafe.MALEUX G., DEMAEREL P., VERBEKEN E., DAENENS K., HEYE S., VANSONHOVEN F., NEVELSTEEN A., WILMS G.: Cerebral ischemia afterfilter-protected carotid artery stenting is common and cannot bepredicted by the presence of substantial amount of debris captured bythe filter device. Am. J. Neuroradiol., <strong>2006</strong>; 27(9): 1830-1833.Purpose: Protected carotid artery stent placement is currently underclinical evaluation as a potential alternative to carotid endarterectomy.The current study was undertaken to determine the incidence of newischemic lesions found on diffusion-weighted MR imaging (DWI) innonselected patients after protected carotid artery stent placementusing a filter device and to determine the potential relationshipbetween these new ischemic lesions and the presence or absence ofa clear amount of debris captured by the neuroprotection filter device.Materials and methods: A nonrandomized cohort of 52 patients (40men, 12 women) presenting with carotid occlusive disease underwentprotected carotid artery stent placement using a filter device. DWIobtained 1 day before stent placement was compared with thatobtained 1 day after stent placement. In addition, the macroscopic andmicroscopic analysis of debris captured by the filter device during thecarotid stent placement procedure was assessed.Results: Neuroprotected carotid stent placement was technicallysuccessful in all 53 procedures but was complicated by a transientischemic attack in 3 patients (5.6%). In 22 patients (41.5%), newischemic lesions were found on DWI, and in 21 filter devices (39.6%),a substantial amount of atheromatous plaque and/or fibrin was found.No clear relationship between the presence of debris captured by thefilter device and new lesions detected by DWI was found (P = .087;odds ratio 3.067).Conclusion: Neuroprotected carotid artery stent placement will notavoid silent cerebral ischemia. Systematic microscopic analysis ofdebris captured by the filter device has no predictive value forpotential cerebral ischemia after carotid artery stent placement.MEESTER D.J., VAN MUISWINKEL K.W., AMEYE F., FRANSEN H.,STOCKX L., MERCKX L., NEVELSTEEN A.: Endovascular treatment of aureteroiliac fistula associated with ureteral double J-stenting and anaortic-bifemoral stent graft for an inflammatory abdominal aorticaneurysm. Ann. Vasc. Surg., <strong>2006</strong>; 20: 408-410.166

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