2006 - UZ Leuven

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defective platelet recruitment in Tsp1-/- mice, while having a moderateeffect in WT mice. Photochemical injury of intestinal blood vesselsinduced thrombotic occlusions with longer occlusion times in Tsp1-/-venules (1027 +/- 377 seconds) and arterioles (858 +/- 289 seconds)than in WT vessels (559 +/- 241 seconds, P < .001; 443 +/- 413seconds, P < .003) due to defective thrombus adherence, resulting inembolization of complete thrombi, a defect restored by both humanTSP-1 and anti-ADAMTS13 antibodies. We conclude that in a shearfield, soluble or local platelet-released TSP-1 can protect unfoldedendothelium-bound and subendothelial VWF from degradation byplasma ADAMTS13, thus securing platelet tethering and thrombusadherence to inflamed and injured endothelium, respectively.DANNEELS M.I.L., VERHAGEN H.J.M., TEIJINK J.A.W., CUYPERS P.,NEVELSTEEN A., VERMASSEN F.E.G.: Endovascular repair for aortoentericfistula: a bridge too far or a bridge to surgery? Eur. J. Vasc.Endovasc. Surg., 2006; 32(1): 27-33.Purpose: To review our experience of endovascular treatment ofaorto-enteric fistula (AEF).Methods: Between March 1999 and March 2005, 15 patients in fiveuniversity and teaching hospitals in Belgium and The Netherlandswere treated for AEF by endovascular repair. Twelve (80%) weremale. The mean age was 67 years. Thirteen (87%) had had previousaortic or iliac surgery, 1.7-307 months before. All patients showedclinical or biochemical signs of bleeding. Eight (53%) were in shock,five (33%) had systemic signs of infection. Eight (53%) patients weretreated in an emergency setting. Ten (67%) were treated with anaortouniiliac device, three (20%) with an aortobiiliac device, one with atube graft and one with occluders only. All patients received antibioticspostoperatively for a prolonged period of time.Results: All AEF were successfully sealed, the 30-days mortality wasnil. Mean hospital stay was 20 (2-81) days. One patient died 2.7months later of postoperative complications, one died of lung cancer.Until now, there are no signs of reinfection in four (27%) patients(mean follow-up 15.7 (1-44) months). However, reinfection orrecurrent AEF occurred in nine (60%) patients after 9.5 (0.61-31)months. Seven patients were reoperated successfully, two patientsdied after reintervention.Conclusion: Endovascular sealing of AEF is a promising technique,which provides time to treat shock, local and systemic infection, andco-morbidity. This creates a better situation to perform open repair inthe future with possibly better outcome. Danger of reinfection remainshigh. Endovascular sealing of AEF should, therefore, be seen as abridge to open surgery when possible.162
FOURNEAU I., SABBE T., DAENENS K., NEVELSTEEN A.: Hand-assistedlaparoscopy versus conventional median laparotomy foraortobifemoral bypass for severe aorto-iliac occlusive disease: aprospective randomised study. Eur. J. Vasc. Endovasc. Surg., 2006; 32:645-650.Objectives: To demonstrate that hand-assisted laparoscopy foraortofemoral bypass for severe aorto-iliac occlusive disease reducesmorbidity with earlier recovery of bowel function and shorter inhospitalstay.Design: Randomised controlled trial.Materials and methods: Thirty-six consecutive patients with severeaorto-iliac occlusive disease (TASK C/D) without history of majorabdominal surgery necessitating an aortobifemoral bypass wererandomised between a hand-assisted laparoscopic (HALS) approachand a conventional medial laparotomy. Operative data, early recoverydata, quality of life and vascular outcome were analysed.Results: No significant differences in operative data were found. Fluidand solid diet were resumed earlier (28.8 hrs vs. 76.9 hrs; p=0.016)(45.6 hrs vs. 105.6 hrs; p=0.02) and in-hospital stay was shorter (7.5vs. 8.9 days; p=0.005) in the HALS group. Six weeks post-operativelysocial functioning measured by the SF-36 survey score was better inpatients randomised to HALS (p=0.023).Conclusions: HALS is a less invasive approach for aortofemoralbypass.GODDEERIS K., DAENENS K., MOULIN-ROMSEE G., BLOCKMANS D.:Chronic-contained rupture of an infected aneurysm of the abdominalaorta due to Listerio monocytogenes. Nederlands J. Med., 2006; 64(3):85-87.We report a case of chronic-contained rupture of an infectedaneurysm of the abdominal aorta, from which Listeria monocytogeneswas cultured. The diagnosis of rupture and retroperitoneal mass wasmade by computed tomography, whereas FDG -PET diagnosedvessel wall inflammation. The infectious nature only became apparentat surgery.HASSEN-KHODJA R., FEUGIER P., FAVRE J.P., NEVELSTEEN A.,FERREIRA J.: Outcome of common iliac arteries after straight aortictube-graft placement during elective repair of infrarenal abdominalaortic aneurysms. J. Vasc. Surg., 2006; 44(5): 943-948.163
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CYRURGIE2006
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Heelmeesters allerhande, verenig u!
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INHOUDSOPGAVEAbdominale Heelkunde 1
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De resultaten van een grote Noord-A
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VEGF (P = 0.008) correlate with a p
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severe ulcerative ileitis and jejun
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tekens op CT en/of MRI kunnen een b
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data we propose a scoring system in
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ABDOMINALETRANSPLANTATIECHIRURGIECA
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DYCKMANS K., LERUT E., GILLARD P.,
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LERUT J., ORLANDO G., ADAM R., SABB
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histopathologic diagnostic process.
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additional stimulants that the inna
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ARTIKELS UIT HETLEUVENSE NETCREVITS
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PRUYT M., DEVRIENDT D., VANNESTE A.
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BOSHOFF D., BUDTS W., MERTENS L., E
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FLAMENG W., MEURIS B., HERIJGERS P.
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prosthetic valve endocarditis who w
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in these patients We present a case
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SERCA2a. In SKO mice, gene-targeted
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MULTIDISCIPLINAIRBORSTCENTRUMMORALE
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east implant. Only two other cases
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Object: Based on data from primate
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SISCOM hyperperfusion cluster and M
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ONCOLOGISCHEHEELKUNDEBROUNS F., SCH
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infiltrative multilobular spindle c
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multivariable Cox model adjusted fo
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We retrospectively evaluated a surg
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We performed resection arthroplasty
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earing posterior-stabilised. To do
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age and key pinch strength. The dif
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FABRY K., LAMMENS J., DELHEY P., ST
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cases. The mean Knee Society’s kn
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short-term solution for his fractur
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the foot and result in major septic
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SAEGEMAN V., LISMONT D., VERDUYCKT
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Objective: The objective of this st
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VICTOR J., BELLEMANS J.: Physiologi
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skin construct displays authentic f
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Bewertung des Spenderdefektes ergab
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HIERNER R., BERGER A.: Options and
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vascularized ulnar nerve graft and
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cranial bone and dura which cannot
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defects.Adequate debridement, early
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Patients and Methods: Between 1995
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MASSAGE P., VANDENHOF B., VRANCKX J
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Background: High pressure injuries
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VERMEULEN P., DICKENS S., VRANCKX J
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inhibitors that neutralize the impa
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internship. These components repres
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Objective: To evaluate the expressi
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patients were diagnosed with acute
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Conclusions: This study demonstrate
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progressive accumulation of FVIII a
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his name to this condition through
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gevallen, beschouwen wij de minimaa
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Table 1Reperfusion time(min)PVR(dyn
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Page 131 and 132: of debate. A good pain relief can b
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Page 137 and 138: children achieve bladder and bowel
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Page 143 and 144: Results: Although the surgery was m
Page 145 and 146: DE RIDDER D.: Conservatieve aanpak
Page 147 and 148: pressures were measured. The effect
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Page 161 and 162: a remarkable higher number of forei
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Page 165 and 166: VANDE WALLE J.G.J., BOGAERT G.A., M
Page 167 and 168: Introduction & Objectives: Control
Page 169: VAATHEELKUNDEBLADT O., MALEUX G., H
Page 173 and 174: computed tomography (CT) and magnet
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2006 - UZ Leuven

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