2006 - UZ Leuven

GOEMAN L., JONIAU S., OYEN R., VAN POPPEL H.: Percutaneousultrasound-guided radiofrequency ablation of recurrent renal cellcarcinoma in renal allograft after partial nephrectomy. Urology, 2006;67(1): 199.Percutaneous thermal ablation is increasingly being studied in thetreatment of renal tumors. Because radiofrequency ablation is aminimally invasive and nephron-sparing procedure, it is ideally suitedfor patients with a single kidney, multiple tumors, or contraindicationsto conventional surgery. We report on a patient with recurrent renalcell carcinoma in a transplanted kidney that was successfully treatedwith percutaneous ultrasound-guided radiofrequency ablation.HSU C.Y., JONIAU S., OYEN R., ROSKAMS T., VAN POPPEL H.: Stagingof unilateral clinical T3A prostate cancer: digital rectal examination ortransrectal ultrasound? Eur. Urol. Suppl., 2006; 5(2): 206 (735).Introduction & Objectives: The long-term outcome of surgicaltreatment for locally advanced prostate cancer (ct3a) is very good andsurpasses radiotherapy outcomes. It is anticipated that surgicalmanagement for cT3a disease will gain importance. Stagingmodalities for cT3a disease are not well studied. The purpose of thisretrospective study is to assess the sensitivity (SENS), specificity(SPEC), positive predictive value (PPV) and negative predictive value(NPV) of digital rectal examination (DRE), transrectal ultrasound(TRUS) and the combination of both in unilateral cT3a prostatecancer.Material & Methods: Between 1990 and 2004, 267 patients werestaged as unilateral cT3a prostate cancer either by DRE and/orTRUS. All patients underwent radical prostatectomy and bilateralpelvic lymphadenectomy. Final histopathology was compared withDRE and TRUS. SENS, SPEC, PPV and NPV for DRE, TRUS andcombination of both were calculated.SENS SPEC PPV NPVDRE 90,9% 15,8% 47,2% 67,7%TRUS 80,2% 25,3% 47,1% 60,7%Combination 71,1% 41,1% 50,0% 63,2%Although the SENS is lower in the combination group, it has thehighest SPEC (41,1%) and PPV (50,0%). Combination of DRE and141