2006 - UZ Leuven

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Conclusions: We believe that nephron sparing surgery for T1 and T2lesions is safe and reproducible with good oncological control atintermediate term follow-up.KIRBY M., ARTIBANI W., CARDOZO L., CHAPPLE C., DIAZ D.C., DERIDDER D., ESPUNA-PONS MP., HAAB F., KELLEHER C., MILSOM I.,VAN KERREBROECK P., VIERHOUT M., WAGG A.: Overactive bladder:the importance of new guidance. Int. J. Clin. Pract., 2006; 60(10): 1263-1271.Overactive bladder (OAB) affects an estimated 49 million people inEurope, but only a minority receive appropriate treatment. Others arebothered by unacceptable levels of symptoms that severely impairtheir quality of life and represent a significant financial burden tothemselves and to their healthcare providers. Recently updatedguidelines from the International Consultation on Incontinence (ICI)and the European Association of Urology (EAU) take account ofimportant new developments in the management of bladder problemsin both primary and secondary care. However, local implementation ofprevious guidance has been variable, with many patients with OABand other bladder problems failing to gain full benefit from currentclinical and scientific understanding of these conditions. The recentexpansion of the range of treatments available for OAB and stressurinary incontinence makes it especially important that physiciansbecome aware of the differential diagnosis of these conditions - thequestions they need to ask, and the investigations which will helpdetermine the most appropriate course of action.KLAVER S., JONIAU S., GOETHUYS H., SUY R., VAN POPPEL H.: Renalcell carcinoma with venous tumour thrombus: prognostic significanceof the level of the tumour thrombus and of associated metastases onlong-term survival. Eur. Urol. Suppl., 2006; 5(2): 258 (942).Introduction & Objectives: To evaluate the significance of venoustumour thrombus (TT) on the long-term outcome in patients withunilateral renal cell carcinoma (RCC) and to what extent the presenceof associated metastases influences survival.Material & Methods: Between January 1990 and June 2003, 87patients with RCC and associated TT were treated at our institution.All patients underwent a radical nephrectomy with resection of TT.The correlation between tumour characteristics (tumour grade andsize, associated metastases) and the level of TT was analysed.Furthermore, the impact of the level of TT and associated metastases146
on overall survival was studied. Survival was calculated using theKaplan-Meier method.Results: Tumour grade (p = 0,200), tumour size (p = 0.057) andpresence of associated metastases (p = 0.1491) were not significantlypredictive for TT level. However, in the group with no apparentmetastases, we found a significantly better 5-year overall survival of55% in patients with TT confined to the renal vein compared to 20% inpatients with TT extending into the IVC (p = 0.0016). We were unableto determine to what extent the level of TT in the IVC influences longtermsurvival due to small sample sizes. Finally, the presence ofassociated metastases clearly impacted survival in the total group,with a 5-year survival of 55% in the group without metastasiscompared to 10% in the group with metastasis (p < 0.0001).Conclusions: The level of TT is not significantly associated withtumour characteristics (grade, size and metastasis). Our data confirmthat non-metastatic RCC with TT is potentially curable condition, witha 5-year overall survival of 55%. However, survival is significantlydifferent for patients with TT extending into the renal vein compared toTT extending into the IVC. In this respect, it might be interesting to reevaluatethe 2002 TNM staging system which combines these twogroups (except IVD involvement extending above the diaphragm)equally as T3b. Radical nephrectomy in patients with TT andassociated metastatic spread yields poor results, with only 10%surviving more than 5 years.KONSTANTINOVIC M.L., PILLE E., MALINOWSKA M., VERBEKEN E., DERIDDER D., DEPREST J.: Tensile strength and host response towardsdifferent polypropylene implant materials used for augmentation offascial repair in a rat model. Int. Urogynecol. J., 2006; oct. 10; (Epubahead of print).We compared inflammatory response, fibrosis and biomechanicalproperties of different polypropylene materials from one manufacturer(Tyco Healthcare) in a rat model for primary fascial repair. Fullthicknessabdominal wall defects were primarily repaired using'overlay' technique. Multifilament implants were Surgipro SPM andSPMW, the latter a wider-weave type of the former. MonofilamentSPMM implants and polypropylene suture repair (Surgipro II) servedas controls. Explants were evaluated macroscopically and changes inthickness, shrinkage and tensile strength were measured.Inflammatory and connective tissue response was assessed onhaematoxylin-eosin and Movat stains. Immunohistochemistry wasdone to localise rat macrophages/monocytes. Multifilament materialsinduced a shorter acute inflammatory response and more pronouncedchronic inflammatory reaction compared to monofilament implants.147
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CYRURGIE2006
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Heelmeesters allerhande, verenig u!
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INHOUDSOPGAVEAbdominale Heelkunde 1
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De resultaten van een grote Noord-A
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VEGF (P = 0.008) correlate with a p
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severe ulcerative ileitis and jejun
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tekens op CT en/of MRI kunnen een b
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data we propose a scoring system in
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ABDOMINALETRANSPLANTATIECHIRURGIECA
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DYCKMANS K., LERUT E., GILLARD P.,
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LERUT J., ORLANDO G., ADAM R., SABB
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histopathologic diagnostic process.
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additional stimulants that the inna
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ARTIKELS UIT HETLEUVENSE NETCREVITS
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PRUYT M., DEVRIENDT D., VANNESTE A.
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BOSHOFF D., BUDTS W., MERTENS L., E
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FLAMENG W., MEURIS B., HERIJGERS P.
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prosthetic valve endocarditis who w
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in these patients We present a case
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SERCA2a. In SKO mice, gene-targeted
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MULTIDISCIPLINAIRBORSTCENTRUMMORALE
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east implant. Only two other cases
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Object: Based on data from primate
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SISCOM hyperperfusion cluster and M
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ONCOLOGISCHEHEELKUNDEBROUNS F., SCH
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infiltrative multilobular spindle c
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multivariable Cox model adjusted fo
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We retrospectively evaluated a surg
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We performed resection arthroplasty
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earing posterior-stabilised. To do
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age and key pinch strength. The dif
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FABRY K., LAMMENS J., DELHEY P., ST
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cases. The mean Knee Society’s kn
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short-term solution for his fractur
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the foot and result in major septic
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SAEGEMAN V., LISMONT D., VERDUYCKT
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Objective: The objective of this st
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VICTOR J., BELLEMANS J.: Physiologi
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skin construct displays authentic f
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Bewertung des Spenderdefektes ergab
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HIERNER R., BERGER A.: Options and
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vascularized ulnar nerve graft and
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cranial bone and dura which cannot
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defects.Adequate debridement, early
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Patients and Methods: Between 1995
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MASSAGE P., VANDENHOF B., VRANCKX J
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Background: High pressure injuries
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VERMEULEN P., DICKENS S., VRANCKX J
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inhibitors that neutralize the impa
Page 103 and 104: internship. These components repres
Page 105 and 106: Objective: To evaluate the expressi
Page 107 and 108: patients were diagnosed with acute
Page 109 and 110: Conclusions: This study demonstrate
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Page 113 and 114: his name to this condition through
Page 115 and 116: gevallen, beschouwen wij de minimaa
Page 117 and 118: Table 1Reperfusion time(min)PVR(dyn
Page 119 and 120: transplantation; dehiscence (n = 25
Page 121 and 122: upon reperfusion results from a red
Page 123 and 124: VAN DE WAUWER C., VAN RAEMDONCK D.E
Page 125 and 126: Bronchiolitis obliterans syndrome (
Page 127 and 128: noodzakelijk een beter inzicht te v
Page 129 and 130: patients of 70 years and older trea
Page 131 and 132: of debate. A good pain relief can b
Page 133 and 134: VAN GESTEL L., NIJS S., BROOS P.: T
Page 135 and 136: UROLOGIEALBERSEN M., JONIAU S., VAN
Page 137 and 138: children achieve bladder and bowel
Page 139 and 140: Results: Ninety-five percent of the
Page 141 and 142: esistant to degradation, but at 365
Page 143 and 144: Results: Although the surgery was m
Page 145 and 146: DE RIDDER D.: Conservatieve aanpak
Page 147 and 148: pressures were measured. The effect
Page 149 and 150: GOEMAN L., JONIAU S., OYEN R., VAN
Page 151 and 152: pelvic lymph node status were not w
Page 153: literature on nephron-sparing surge
Page 157 and 158: materials, although it was architec
Page 159 and 160: Material und Methoden: Von 13 Zentr
Page 161 and 162: a remarkable higher number of forei
Page 163 and 164: VAN CALSTEREN K., VAN MENSEL K., JO
Page 165 and 166: VANDE WALLE J.G.J., BOGAERT G.A., M
Page 167 and 168: Introduction & Objectives: Control
Page 169 and 170: VAATHEELKUNDEBLADT O., MALEUX G., H
Page 171 and 172: FOURNEAU I., SABBE T., DAENENS K.,
Page 173 and 174: computed tomography (CT) and magnet
Page 175 and 176: We report an unusual case of a uret
Page 177: during GPIb stimulation, its activa
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2006 - UZ Leuven

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