2006 - UZ Leuven

that presented with Legg-CalvéPerthes disease in the early stagewere followed with serial bone scintigraphy and radiographs. Fortyfourhips showed recanalization: pathway A on bone scintigraphy. Ofthese hips 96% were classified as Herring A or B and 66% as Catterall2. Thirty-five hips showed revascularization: pathway B on bonescintigraphy. Of this group 82.8% were classified as Herring C and17.1% as Herring B. All pathway B hips have Catterall 3 or 4. Sixteenhips showed pathway C: regression from pathway A to pathway B.They presented in 56% of cases with Herring B, 44% with Herring C,and in 81% with Catterall 3 or 4 classifications. We can conclude thatthere is a significant correlation between the vascularization patternand the radiographic classification of Herring and Catterall.VAN DEN BEKEROM M.P.J., STUYCK J.: The value of pre-operativeaspiration in the diagnosis of an infected prosthetic knee: aretrospective study and review of literature. Acta Orthop. Belg., 2006; 72:441-447.The purpose of this study was to compare the results of cultures ofpreoperative aspiration samples with those of swabs taken intraoperatively.The records of 70 revision arthroplasties of the knee from69 patients, 49 females and 20 males, were reviewed. The mean ageof the patients at time of revision arthroplasty was 67 years (range: 34to 89). Sixty-eight knees from 67 patients were included. There were32 true positives, 17 true negatives, 6 false positives and 13 falsenegatives. This led to a specificity, sensitivity and accuracy of 57%,84% and 72%, respectively. Based on these findings, pre-operativeaspiration has a positive predictive value of 71% and a negativepredictive value of 74%. When the aspiration sample yields a positiveculture, the chances are high that the prosthetic knee is infected.When aspiration is negative, infection cannot be ruled out. Our studysuggests that, in such cases, a coagulase negative Staphylococcus(CNS) infection has to be considered.VAN ESCH H., AGARWAL A.K., DEBEER P., FRYNS J.P. and GARG A.: Ahomozygous mutation in the lamin A/C gene associated with a novelsyndrome of arthropathy, tendinous calcinosis, and progeroid features.J. Clin. Endocrinol. Metab., 2006; 91(2): 517-521.Context: Mutations in the lamin A/C (LMNA) gene have been reportedin a wide variety of disorders, including lipodystrophies,cardiomyopathy, muscular dystrophies, neuropathy, mandibuloacraldysplasia, restrictive dermopathy, and progeria.68